Xiaohong Liu

Rongsheng Wang, Yaofei Duan, ChanTong Lam et al.

General large language models (LLMs) such as ChatGPT have shown remarkable success. However, such LLMs have not been widely adopted for medical purposes, due to poor accuracy and inability to provide medical advice. We propose IvyGPT, an LLM based on LLaMA that is trained and fine-tuned with high-quality medical question-answer (QA) instances and Reinforcement Learning from Human Feedback (RLHF). After supervised fine-tuning, IvyGPT has good multi-turn conversation capabilities, but it cannot perform like a doctor in other aspects, such as comprehensive diagnosis. Through RLHF, IvyGPT can output richer diagnosis and treatment answers that are closer to human. In the training, we used QLoRA to train 33 billion parameters on a small number of NVIDIA A100 (80GB) GPUs. Experimental results show that IvyGPT has outperformed other medical GPT models.

Xiaohong Liu, Guoxing Yang, Yulin Luo et al.

Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in medicine have shown potential in processing multimodal information, offering a unified solution for various radiology tasks. However, existing studies either pre-trained VL models on natural data or did not fully integrate vision-language architecture and pretraining, often neglecting the unique multimodal complexity in radiology images and their textual contexts. Additionally, their practical applicability in real-world scenarios remains underexplored. Here, we present RadFound, a large and open-source vision-language foundation model tailored for radiology, that is trained on the most extensive dataset of over 8.1 million images and 250,000 image-text pairs, covering 19 major organ systems and 10 imaging modalities. To establish expert-level multimodal perception and generation capabilities, RadFound introduces an enhanced vision encoder to capture intra-image local features and inter-image contextual information, and a unified cross-modal learning design tailored to radiology. To fully assess the models' capability, we construct a benchmark, RadVLBench, including radiology interpretation tasks like medical vision-language question-answering, as well as text generation tasks ranging from captioning to report generation. We also propose a human evaluation framework. When evaluated on the real-world benchmark involving three representative modalities, 2D images (chest X-rays), multi-view images (mammograms), and 3D images (thyroid CT scans), RadFound significantly outperforms other VL foundation models on both quantitative metrics and human evaluation. In summary, the development of RadFound represents an advancement in radiology generalists, demonstrating broad applicability potential for integration into clinical workflows.

Yinfeng Yu, Lele Cao, Fuchun Sun et al. · tsinghua

Audio-visual embodied navigation, as a hot research topic, aims training a robot to reach an audio target using egocentric visual (from the sensors mounted on the robot) and audio (emitted from the target) input. The audio-visual information fusion strategy is naturally important to the navigation performance, but the state-of-the-art methods still simply concatenate the visual and audio features, potentially ignoring the direct impact of context. Moreover, the existing approaches requires either phase-wise training or additional aid (e.g. topology graph and sound semantics). Up till this date, the work that deals with the more challenging setup with moving target(s) is still rare. As a result, we propose an end-to-end framework FSAAVN (feature self-attention audio-visual navigation) to learn chasing after a moving audio target using a context-aware audio-visual fusion strategy implemented as a self-attention module. Our thorough experiments validate the superior performance (both quantitatively and qualitatively) of FSAAVN in comparison with the state-of-the-arts, and also provide unique insights about the choice of visual modalities, visual/audio encoder backbones and fusion patterns.

Guoxing Yang, Jianyu Shi, Zan Wang et al.

Pre-training and fine-tuning have emerged as a promising paradigm across various natural language processing (NLP) tasks. The effectiveness of pretrained large language models (LLM) has witnessed further enhancement, holding potential for applications in the field of medicine, particularly in the context of Traditional Chinese Medicine (TCM). However, the application of these general models to specific domains often yields suboptimal results, primarily due to challenges like lack of domain knowledge, unique objectives, and computational efficiency. Furthermore, their effectiveness in specialized domains, such as Traditional Chinese Medicine, requires comprehensive evaluation. To address the above issues, we propose a novel domain specific TCMDA (TCM Domain Adaptation) approach, efficient pre-training with domain-specific corpus. Specifically, we first construct a large TCM-specific corpus, TCM-Corpus-1B, by identifying domain keywords and retreving from general corpus. Then, our TCMDA leverages the LoRA which freezes the pretrained model's weights and uses rank decomposition matrices to efficiently train specific dense layers for pre-training and fine-tuning, efficiently aligning the model with TCM-related tasks, namely TCM-GPT-7B. We further conducted extensive experiments on two TCM tasks, including TCM examination and TCM diagnosis. TCM-GPT-7B archived the best performance across both datasets, outperforming other models by relative increments of 17% and 12% in accuracy, respectively. To the best of our knowledge, our study represents the pioneering validation of domain adaptation of a large language model with 7 billion parameters in TCM domain. We will release both TCMCorpus-1B and TCM-GPT-7B model once accepted to facilitate interdisciplinary development in TCM and NLP, serving as the foundation for further study.

Xiufeng Song, Xiao Guo, Jiache Zhang et al.

Large numbers of synthesized videos from diffusion models pose threats to information security and authenticity, leading to an increasing demand for generated content detection. However, existing video-level detection algorithms primarily focus on detecting facial forgeries and often fail to identify diffusion-generated content with a diverse range of semantics. To advance the field of video forensics, we propose an innovative algorithm named Multi-Modal Detection(MM-Det) for detecting diffusion-generated videos. MM-Det utilizes the profound perceptual and comprehensive abilities of Large Multi-modal Models (LMMs) by generating a Multi-Modal Forgery Representation (MMFR) from LMM's multi-modal space, enhancing its ability to detect unseen forgery content. Besides, MM-Det leverages an In-and-Across Frame Attention (IAFA) mechanism for feature augmentation in the spatio-temporal domain. A dynamic fusion strategy helps refine forgery representations for the fusion. Moreover, we construct a comprehensive diffusion video dataset, called Diffusion Video Forensics (DVF), across a wide range of forgery videos. MM-Det achieves state-of-the-art performance in DVF, demonstrating the effectiveness of our algorithm. Both source code and DVF are available at https://github.com/SparkleXFantasy/MM-Det.

Yuning Yang, Han Yu, Chuan Sun et al.

Federated Learning (FL) is a collaborative machine learning paradigm for training models on local sensitive data with privacy protection. Pre-trained transformer-based models have emerged as useful foundation models (FMs) to be fine-tuned for a wide range of downstream tasks. However, large-scale pre-trained models make it challenging for traditional FL due to high communication overhead in the resource-constrained IoT. This has inspired the field of parameter-efficient fine-tuning (PEFT) research. Existing PEFT methods attempt to optimize model performance at the given dropout level. Such an approach places the burden on human users to find a dropout rate that provides a satisfactory level of performance through trial-and-error, which is time consuming and resource intensive. To address this limitation, we propose the Step-wise Parameter Dropout for Continual Federated Learning (SPD-CFL) approach. Instead of pre-defining a desired dropout rate, it allows users to specify the target level of performance and then attempts to find the most suitable dropout rate for the given FL model. Specifically, on the server side, SPD-CFL drops trainable parameters in a stepwise manner to improve communication efficiency by reducing the rank of low-rank adaptation (LoRA). The sensitivity-based gradient consistency (SGC) measure is designed to facilitate the adaptive adjustment of parameter dropout. In addition, SPD-CFL introduces continual learning (CL) on the client side to mitigate performance degradation due to the inconsistent optima with distinct parameter dropout rates under heterogeneous FL. Extensive experiments on the public benchmark dataset CIFAR-10 and a real-world medical Face dataset demonstrate significant superiority of SPD-CFL over state-of-the-art methods. Compared to the best-performing baseline, it achieves a 2.07% higher test AUC while reducing communication overhead by 29.53%.

Haijiang Tian, Jingkun Yue, Xiaohong Liu et al.

Medical images are often more difficult to acquire than natural images due to the specialism of the equipment and technology, which leads to less medical image datasets. So it is hard to train a strong pretrained medical vision model. How to make the best of natural pretrained vision model and adapt in medical domain still pends. For image classification, a popular method is linear probe (LP). However, LP only considers the output after feature extraction. Yet, there exists a gap between input medical images and natural pretrained vision model. We introduce visual prompting (VP) to fill in the gap, and analyze the strategies of coupling between LP and VP. We design a joint learning loss function containing categorisation loss and discrepancy loss, which describe the variance of prompted and plain images, naming this joint training strategy MoVL (Mixture of Visual Prompting and Linear Probe). We experiment on 4 medical image classification datasets, with two mainstream architectures, ResNet and CLIP. Results shows that without changing the parameters and architecture of backbone model and with less parameters, there is potential for MoVL to achieve full finetune (FF) accuracy (on four medical datasets, average 90.91% for MoVL and 91.13% for FF). On out of distribution medical dataset, our method(90.33%) can outperform FF (85.15%) with absolute 5.18 % lead.

Hongwei Liu, Junnan Liu, Shudong Liu et al.

The rapid advancement of Large Language Models (LLMs) has led to performance saturation on many established benchmarks, questioning their ability to distinguish frontier models. Concurrently, existing high-difficulty benchmarks often suffer from narrow disciplinary focus, oversimplified answer formats, and vulnerability to data contamination, creating a fidelity gap with real-world scientific inquiry. To address these challenges, we introduce ATLAS (AGI-Oriented Testbed for Logical Application in Science), a large-scale, high-difficulty, and cross-disciplinary evaluation suite composed of approximately 800 original problems. Developed by domain experts (PhD-level and above), ATLAS spans seven core scientific fields: mathematics, physics, chemistry, biology, computer science, earth science, and materials science. Its key features include: (1) High Originality and Contamination Resistance, with all questions newly created or substantially adapted to prevent test data leakage; (2) Cross-Disciplinary Focus, designed to assess models' ability to integrate knowledge and reason across scientific domains; (3) High-Fidelity Answers, prioritizing complex, open-ended answers involving multi-step reasoning and LaTeX-formatted expressions over simple multiple-choice questions; and (4) Rigorous Quality Control, employing a multi-stage process of expert peer review and adversarial testing to ensure question difficulty, scientific value, and correctness. We also propose a robust evaluation paradigm using a panel of LLM judges for automated, nuanced assessment of complex answers. Preliminary results on leading models demonstrate ATLAS's effectiveness in differentiating their advanced scientific reasoning capabilities. We plan to develop ATLAS into a long-term, open, community-driven platform to provide a reliable "ruler" for progress toward Artificial General Intelligence.

Liangyan Li, Yimo Ning, Kevin Le et al.

This paper introduces a novel framework for image and video demoiréing by integrating Maximum A Posteriori (MAP) estimation with advanced deep learning techniques. Demoiréing addresses inherently nonlinear degradation processes, which pose significant challenges for existing methods. Traditional supervised learning approaches either fail to remove moiré patterns completely or produce overly smooth results. This stems from constrained model capacity and scarce training data, which inadequately represent the clean image distribution and hinder accurate reconstruction of ground-truth images. While generative models excel in image restoration for linear degradations, they struggle with nonlinear cases such as demoiréing and often introduce artifacts. To address these limitations, we propose a hybrid MAP-based framework that integrates two complementary components. The first is a supervised learning model enhanced with efficient linear attention Test-Time Training (TTT) modules, which directly learn nonlinear mappings for RAW-to-sRGB demoiréing. The second is a Truncated Flow Matching Prior (TFMP) that further refines the outputs by aligning them with the clean image distribution, effectively restoring high-frequency details and suppressing artifacts. These two components combine the computational efficiency of linear attention with the refinement abilities of generative models, resulting in improved restoration performance.

Yinfeng Yu, Wenbing Huang, Fuchun Sun et al.

Audio-visual navigation task requires an agent to find a sound source in a realistic, unmapped 3D environment by utilizing egocentric audio-visual observations. Existing audio-visual navigation works assume a clean environment that solely contains the target sound, which, however, would not be suitable in most real-world applications due to the unexpected sound noise or intentional interference. In this work, we design an acoustically complex environment in which, besides the target sound, there exists a sound attacker playing a zero-sum game with the agent. More specifically, the attacker can move and change the volume and category of the sound to make the agent suffer from finding the sounding object while the agent tries to dodge the attack and navigate to the goal under the intervention. Under certain constraints to the attacker, we can improve the robustness of the agent towards unexpected sound attacks in audio-visual navigation. For better convergence, we develop a joint training mechanism by employing the property of a centralized critic with decentralized actors. Experiments on two real-world 3D scan datasets, Replica, and Matterport3D, verify the effectiveness and the robustness of the agent trained under our designed environment when transferred to the clean environment or the one containing sound attackers with random policy. Project: \url{https://yyf17.github.io/SAAVN}.

Xiaohong Liu, Yaojie Liu, Jun Chen et al.

To defend against manipulation of image content, such as splicing, copy-move, and removal, we develop a Progressive Spatio-Channel Correlation Network (PSCC-Net) to detect and localize image manipulations. PSCC-Net processes the image in a two-path procedure: a top-down path that extracts local and global features and a bottom-up path that detects whether the input image is manipulated, and estimates its manipulation masks at multiple scales, where each mask is conditioned on the previous one. Different from the conventional encoder-decoder and no-pooling structures, PSCC-Net leverages features at different scales with dense cross-connections to produce manipulation masks in a coarse-to-fine fashion. Moreover, a Spatio-Channel Correlation Module (SCCM) captures both spatial and channel-wise correlations in the bottom-up path, which endows features with holistic cues, enabling the network to cope with a wide range of manipulation attacks. Thanks to the light-weight backbone and progressive mechanism, PSCC-Net can process 1,080P images at 50+ FPS. Extensive experiments demonstrate the superiority of PSCC-Net over the state-of-the-art methods on both detection and localization.