Sishen Yuan

Sishen Yuan, Baijia Liang, Tangyou Liu et al.

Multicellular coordination relies on broadcast-addressable receptors, yet engineered magnetic systems face an addressability bottleneck because global fields intrinsically conflate power and control. Here, we introduce MagCeptors to resolve this by encoding selectivity directly into magnetic topology. Establishing an energetic isomorphism with biological receptors, these arrays utilize local couplings to shape potential landscapes where global field vectors act as spatial keys, triggering deterministic snap-through instabilities. This architecture decouples force from source distance, achieving a density of 385 mN/mm3 (>50-fold increase over prior art). We validate this primitive through signal demultiplexing, embodied sequential logic, and untethered distributed networking. This framework enables distributed systems to orchestrate complex tasks without tethers or electronics, relying solely on the intrinsic logic of matter.

Haoxuan Wu, Sishen Yuan, Haitao Gao et al.

Wireless capsule endoscopy (WCE) enables painless visualization of the gastrointestinal tract, but its diagnostic potential is limited by incomplete mucosal coverage and poor transferability of existing navigation methods across patient anatomies. We propose a transferable, anatomical landmarkguided deep reinforcement learning (AL-DRL) framework for autonomous gastric navigation. Leveraging a lightweight edgecontour-depth fusion module, our policy operates on stable, lowdimensional landmark coordinates rather than high-dimensional video streams, effectively bridging the sim-to-real gap. In simulations across eight patient-derived models, the method achieves over 97% coverage within 50 seconds, significantly outperforming vanilla PPO, SAC, and DQN agents. A two-stage sim-to-real pipeline with an adaptive dynamic programming controller actively mitigates physical disturbances. Ex-vivo experiments demonstrate a mean coverage of 87% and a 53% reduction in procedure time compared with expert manual control.

Long Bai, Beilei Cui, Liangyu Wang et al.

Deep learning can predict depth maps and capsule ego-motion from capsule endoscopy videos, aiding in 3D scene reconstruction and lesion localization. However, the collisions of the capsule endoscopies within the gastrointestinal tract cause vibration perturbations in the training data. Existing solutions focus solely on vision-based processing, neglecting other auxiliary signals like vibrations that could reduce noise and improve performance. Therefore, we propose V$^2$-SfMLearner, a multimodal approach integrating vibration signals into vision-based depth and capsule motion estimation for monocular capsule endoscopy. We construct a multimodal capsule endoscopy dataset containing vibration and visual signals, and our artificial intelligence solution develops an unsupervised method using vision-vibration signals, effectively eliminating vibration perturbations through multimodal learning. Specifically, we carefully design a vibration network branch and a Fourier fusion module, to detect and mitigate vibration noises. The fusion framework is compatible with popular vision-only algorithms. Extensive validation on the multimodal dataset demonstrates superior performance and robustness against vision-only algorithms. Without the need for large external equipment, our V$^2$-SfMLearner has the potential for integration into clinical capsule robots, providing real-time and dependable digestive examination tools. The findings show promise for practical implementation in clinical settings, enhancing the diagnostic capabilities of doctors.

Long Bai, Tong Chen, Qiaozhi Tan et al.

Wireless Capsule Endoscopy (WCE) is highly valued for its non-invasive and painless approach, though its effectiveness is compromised by uneven illumination from hardware constraints and complex internal dynamics, leading to overexposed or underexposed images. While researchers have discussed the challenges of low-light enhancement in WCE, the issue of correcting for different exposure levels remains underexplored. To tackle this, we introduce EndoUIC, a WCE unified illumination correction solution using an end-to-end promptable diffusion transformer (DiT) model. In our work, the illumination prompt module shall navigate the model to adapt to different exposure levels and perform targeted image enhancement, in which the Adaptive Prompt Integration (API) and Global Prompt Scanner (GPS) modules shall further boost the concurrent representation learning between the prompt parameters and features. Besides, the U-shaped restoration DiT model shall capture the long-range dependencies and contextual information for unified illumination restoration. Moreover, we present a novel Capsule-endoscopy Exposure Correction (CEC) dataset, including ground-truth and corrupted image pairs annotated by expert photographers. Extensive experiments against a variety of state-of-the-art (SOTA) methods on four datasets showcase the effectiveness of our proposed method and components in WCE illumination restoration, and the additional downstream experiments further demonstrate its utility for clinical diagnosis and surgical assistance.