An efficient framework based on large foundation model for cervical cytopathology whole slide image screeningJialong Huang, Gaojie Li, Shichao Kan et al.
Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a weakly supervised approach that relies solely on bag-level labels, can effectively alleviate these challenges. Nonetheless, MIL commonly employs frozen pretrained models or self-supervised learning for feature extraction, which suffers from low efficacy or inefficiency. In this paper, we propose an efficient framework for cervical cytopathology WSI classification using only WSI-level labels through unsupervised and weakly supervised learning. Given the sparse and dispersed nature of abnormal cells within cytopathological WSIs, we propose a strategy that leverages the pretrained foundation model to filter the top$k$ high-risk patches. Subsequently, we suggest parameter-efficient fine-tuning (PEFT) of a large foundation model using contrastive learning on the filtered patches to enhance its representation ability for task-specific signals. By training only the added linear adapters, we enhance the learning of patch-level features with substantially reduced time and memory consumption. Experiments conducted on the CSD and FNAC 2019 datasets demonstrate that the proposed method enhances the performance of various MIL methods and achieves state-of-the-art (SOTA) performance. The code and trained models are publicly available at https://github.com/CVIU-CSU/TCT-InfoNCE.
$Se^2$: Sequential Example Selection for In-Context LearningHaoyu Liu, Jianfeng Liu, Shaohan Huang et al.
The remarkable capability of large language models (LLMs) for in-context learning (ICL) needs to be activated by demonstration examples. Prior work has extensively explored the selection of examples for ICL, predominantly following the "select then organize" paradigm, such approaches often neglect the internal relationships between examples and exist an inconsistency between the training and inference. In this paper, we formulate the problem as a $Se$quential $Se$lection problem and introduce $Se^2$, a sequential-aware method that leverages the LLM's feedback on varying context, aiding in capturing inter-relationships and sequential information among examples, significantly enriching the contextuality and relevance of ICL prompts. Meanwhile, we utilize beam search to seek and construct example sequences, enhancing both quality and diversity. Extensive experiments across 23 NLP tasks from 8 distinct categories illustrate that $Se^2$ markedly surpasses competitive baselines and achieves 42\% relative improvement over random selection. Further in-depth analysis shows the effectiveness of proposed strategies, highlighting $Se^2$'s exceptional stability and adaptability across various scenarios. Code available at https://github.com/microsoft/LMOps.
GeAR: Generation Augmented RetrievalHaoyu Liu, Shaohan Huang, Jianfeng Liu et al.
Document retrieval techniques are essential for developing large-scale information systems. The common approach involves using a bi-encoder to compute the semantic similarity between a query and documents. However, the scalar similarity often fail to reflect enough information, hindering the interpretation of retrieval results. In addition, this process primarily focuses on global semantics, overlooking the finer-grained semantic relationships between the query and the document's content. In this paper, we introduce a novel method, $\textbf{Ge}$neration $\textbf{A}$ugmented $\textbf{R}$etrieval ($\textbf{GeAR}$), which not only improves the global document-query similarity through contrastive learning, but also integrates well-designed fusion and decoding modules. This enables GeAR to generate relevant context within the documents based on a given query, facilitating learning to retrieve local fine-grained information. Furthermore, when used as a retriever, GeAR does not incur any additional computational cost over bi-encoders. GeAR exhibits competitive retrieval performance across diverse scenarios and tasks. Moreover, qualitative analysis and the results generated by GeAR provide novel insights into the interpretation of retrieval results. The code, data, and models will be released at \href{https://github.com/microsoft/LMOps}{https://github.com/microsoft/LMOps}.
Efficient Misalignment-Robust Multi-Focus Microscopical Images FusionYixiong Liang, Yuan Mao, Zhihong Tang et al.
In this paper we propose a very efficient method to fuse the unregistered multi-focus microscopical images based on the speed-up robust features (SURF). Our method follows the pipeline of first registration and then fusion. However, instead of treating the registration and fusion as two completely independent stage, we propose to reuse the determinant of the approximate Hessian generated in SURF detection stage as the corresponding salient response for the final image fusion, thus it enables nearly cost-free saliency map generation. In addition, due to the adoption of SURF scale space representation, our method can generate scale-invariant saliency map which is desired for scale-invariant image fusion. We present an extensive evaluation on the dataset consisting of several groups of unregistered multi-focus 4K ultra HD microscopic images with size of 4112 x 3008. Compared with the state-of-the-art multi-focus image fusion methods, our method is much faster and achieve better results in the visual performance. Our method provides a flexible and efficient way to integrate complementary and redundant information from multiple multi-focus ultra HD unregistered images into a fused image that contains better description than any of the individual input images. Code is available at https://github.com/yiqingmy/JointRF.