Long Chen

Liqun Huang, Long Chen, Baihai Zhang et al.

Brain tumor segmentation remains a challenge in medical image segmentation tasks. With the application of transformer in various computer vision tasks, transformer blocks show the capability of learning long-distance dependency in global space, which is complementary with CNNs. In this paper, we proposed a novel transformer-based generative adversarial network to automatically segment brain tumors with multi-modalities MRI. Our architecture consists of a generator and a discriminator, which are trained in min-max game progress. The generator is based on a typical "U-shaped" encoder-decoder architecture, whose bottom layer is composed of transformer blocks with resnet. Besides, the generator is trained with deep supervision technology. The discriminator we designed is a CNN-based network with multi-scale $L_{1}$ loss, which is proved to be effective for medical semantic image segmentation. To validate the effectiveness of our method, we conducted experiments on BRATS2015 dataset, achieving comparable or better performance than previous state-of-the-art methods.

Hongxiang Li, Yaowei Li, Yuhang Yang et al.

Controllable human image animation aims to generate videos from reference images using driving videos. Due to the limited control signals provided by sparse guidance (e.g., skeleton pose), recent works have attempted to introduce additional dense conditions (e.g., depth map) to ensure motion alignment. However, such strict dense guidance impairs the quality of the generated video when the body shape of the reference character differs significantly from that of the driving video. In this paper, we present DisPose to mine more generalizable and effective control signals without additional dense input, which disentangles the sparse skeleton pose in human image animation into motion field guidance and keypoint correspondence. Specifically, we generate a dense motion field from a sparse motion field and the reference image, which provides region-level dense guidance while maintaining the generalization of the sparse pose control. We also extract diffusion features corresponding to pose keypoints from the reference image, and then these point features are transferred to the target pose to provide distinct identity information. To seamlessly integrate into existing models, we propose a plug-and-play hybrid ControlNet that improves the quality and consistency of generated videos while freezing the existing model parameters. Extensive qualitative and quantitative experiments demonstrate the superiority of DisPose compared to current methods. Project page: \href{https://github.com/lihxxx/DisPose}{https://github.com/lihxxx/DisPose}.

Long Chen, Liben Chen, Binfeng Xu et al.

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent call, methods for early detection of Alzheimer's disease have been developed for prevention and pre-treatment. Notably, literature on the application of deep learning in the automatic detection of the disease has been proliferating. This study builds upon previous literature and maintains a focus on leveraging multi-modal information to enhance automatic detection. We aim to predict the stage of the disease - Cognitively Normal (CN), Mildly Cognitive Impairment (MCI), and Alzheimer's Disease (AD), based on two different types of brain MRI scans. We design an AlexNet-based deep learning model that learns the synergy of complementary information from both T1 and FLAIR MRI scans.

Yanghao Wang, Zhen Wang, Long Chen

Recent advances in pre-trained text-to-image flow models have enabled remarkable progress in text-based image editing. Mainstream approaches always adopt a corruption-then-restoration paradigm, where the source image is first corrupted into an ``intermediate state'' and then restored to the target image under the prompt guidance. However, current methods construct this intermediate state in a target-agnostic manner, i.e., they primarily focus on realizing source image reconstruction while neglecting the semantic gaps towards the specific editing target. This design inherently results in limited editability or inconsistency when the desired modifications substantially deviate from the source. In this paper, we argue that the intermediate state should be target-aware, i.e., selectively corrupting editing-relevant contents while preserving editing-irrelevant ones. To this end, we propose FlowCycle, a novel inversion-free and flow-based editing framework that parameterizes corruption with learnable noises and optimizes them through a cycle-consistent process. By iteratively editing the source to the target and recovering back to the source with dual consistency constraints, FlowCycle learns to produce a target-aware intermediate state, enabling faithful modifications while preserving source consistency. Extensive ablations have demonstrated that FlowCycle achieves superior editing quality and consistency over state-of-the-art methods.

Zhihua Liu, Lei Tong, Zheheng Jiang et al.

Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown promising performance in solving various computer vision problems, such as image classification, object detection and semantic segmentation. A number of deep learning based methods have been applied to brain tumor segmentation and achieved promising results. Considering the remarkable breakthroughs made by state-of-the-art technologies, we use this survey to provide a comprehensive study of recently developed deep learning based brain tumor segmentation techniques. More than 100 scientific papers are selected and discussed in this survey, extensively covering technical aspects such as network architecture design, segmentation under imbalanced conditions, and multi-modality processes. We also provide insightful discussions for future development directions.

Zhihua Liu, Lei Tong, Long Chen et al.

Automated segmentation of brain glioma plays an active role in diagnosis decision, progression monitoring and surgery planning. Based on deep neural networks, previous studies have shown promising technologies for brain glioma segmentation. However, these approaches lack powerful strategies to incorporate contextual information of tumor cells and their surrounding, which has been proven as a fundamental cue to deal with local ambiguity. In this work, we propose a novel approach named Context-Aware Network (CANet) for brain glioma segmentation. CANet captures high dimensional and discriminative features with contexts from both the convolutional space and feature interaction graphs. We further propose context guided attentive conditional random fields which can selectively aggregate features. We evaluate our method using publicly accessible brain glioma segmentation datasets BRATS2017, BRATS2018 and BRATS2019. The experimental results show that the proposed algorithm has better or competitive performance against several State-of-The-Art approaches under different segmentation metrics on the training and validation sets.