Xuesong Wang

Xuesong Wang, Lina Yao, Islem Rekik et al.

Contrastive self-supervised learning has recently benefited fMRI classification with inductive biases. Its weak label reliance prevents overfitting on small medical datasets and tackles the high intraclass variances. Nonetheless, existing contrastive methods generate resemblant pairs only on pixel-level features of 3D medical images, while the functional connectivity that reveals critical cognitive information is under-explored. Additionally, existing methods predict labels on individual contrastive representation without recognizing neighbouring information in the patient group, whereas interpatient contrast can act as a similarity measure suitable for population-based classification. We hereby proposed contrastive functional connectivity graph learning for population-based fMRI classification. Representations on the functional connectivity graphs are "repelled" for heterogeneous patient pairs meanwhile homogeneous pairs "attract" each other. Then a dynamic population graph that strengthens the connections between similar patients is updated for classification. Experiments on a multi-site dataset ADHD200 validate the superiority of the proposed method on various metrics. We initially visualize the population relationships and exploit potential subtypes.

Xuesong Wang, Lina Yao, Xianzhi Wang et al.

The ability to deal with uncertainty in machine learning models has become equally, if not more, crucial to their predictive ability itself. For instance, during the pandemic, governmental policies and personal decisions are constantly made around uncertainties. Targeting this, Neural Process Families (NPFs) have recently shone a light on prediction with uncertainties by bridging Gaussian processes and neural networks. Latent neural process, a member of NPF, is believed to be capable of modelling the uncertainty on certain points (local uncertainty) as well as the general function priors (global uncertainties). Nonetheless, some critical questions remain unresolved, such as a formal definition of global uncertainties, the causality behind global uncertainties, and the manipulation of global uncertainties for generative models. Regarding this, we build a member GloBal Convolutional Neural Process(GBCoNP) that achieves the SOTA log-likelihood in latent NPFs. It designs a global uncertainty representation p(z), which is an aggregation on a discretized input space. The causal effect between the degree of global uncertainty and the intra-task diversity is discussed. The learnt prior is analyzed on a variety of scenarios, including 1D, 2D, and a newly proposed spatial-temporal COVID dataset. Our manipulation of the global uncertainty not only achieves generating the desired samples to tackle few-shot learning, but also enables the probability evaluation on the functional priors.