A graph-transformer for whole slide image classificationYi Zheng, Rushin H. Gindra, Emily J. Green et al.
Deep learning is a powerful tool for whole slide image (WSI) analysis. Typically, when performing supervised deep learning, a WSI is divided into small patches, trained and the outcomes are aggregated to estimate disease grade. However, patch-based methods introduce label noise during training by assuming that each patch is independent with the same label as the WSI and neglect overall WSI-level information that is significant in disease grading. Here we present a Graph-Transformer (GT) that fuses a graph-based representation of an WSI and a vision transformer for processing pathology images, called GTP, to predict disease grade. We selected $4,818$ WSIs from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), the National Lung Screening Trial (NLST), and The Cancer Genome Atlas (TCGA), and used GTP to distinguish adenocarcinoma (LUAD) and squamous cell carcinoma (LSCC) from adjacent non-cancerous tissue (normal). First, using NLST data, we developed a contrastive learning framework to generate a feature extractor. This allowed us to compute feature vectors of individual WSI patches, which were used to represent the nodes of the graph followed by construction of the GTP framework. Our model trained on the CPTAC data achieved consistently high performance on three-label classification (normal versus LUAD versus LSCC: mean accuracy$= 91.2$ $\pm$ $2.5\%$) based on five-fold cross-validation, and mean accuracy $= 82.3$ $\pm$ $1.0\%$ on external test data (TCGA). We also introduced a graph-based saliency mapping technique, called GraphCAM, that can identify regions that are highly associated with the class label. Our findings demonstrate GTP as an interpretable and effective deep learning framework for WSI-level classification.
7.7LGJan 10, 2023
Differentiable modeling to unify machine learning and physical models and advance GeosciencesChaopeng Shen, Alison P. Appling, Pierre Gentine et al.
Process-Based Modeling (PBM) and Machine Learning (ML) are often perceived as distinct paradigms in the geosciences. Here we present differentiable geoscientific modeling as a powerful pathway toward dissolving the perceived barrier between them and ushering in a paradigm shift. For decades, PBM offered benefits in interpretability and physical consistency but struggled to efficiently leverage large datasets. ML methods, especially deep networks, presented strong predictive skills yet lacked the ability to answer specific scientific questions. While various methods have been proposed for ML-physics integration, an important underlying theme -- differentiable modeling -- is not sufficiently recognized. Here we outline the concepts, applicability, and significance of differentiable geoscientific modeling (DG). "Differentiable" refers to accurately and efficiently calculating gradients with respect to model variables, critically enabling the learning of high-dimensional unknown relationships. DG refers to a range of methods connecting varying amounts of prior knowledge to neural networks and training them together, capturing a different scope than physics-guided machine learning and emphasizing first principles. Preliminary evidence suggests DG offers better interpretability and causality than ML, improved generalizability and extrapolation capability, and strong potential for knowledge discovery, while approaching the performance of purely data-driven ML. DG models require less training data while scaling favorably in performance and efficiency with increasing amounts of data. With DG, geoscientists may be better able to frame and investigate questions, test hypotheses, and discover unrecognized linkages.
31.8CLApr 12, 2022
Delving Deep into Regularity: A Simple but Effective Method for Chinese Named Entity RecognitionYingjie Gu, Xiaoye Qu, Zhefeng Wang et al.
Recent years have witnessed the improving performance of Chinese Named Entity Recognition (NER) from proposing new frameworks or incorporating word lexicons. However, the inner composition of entity mentions in character-level Chinese NER has been rarely studied. Actually, most mentions of regular types have strong name regularity. For example, entities end with indicator words such as "company" or "bank" usually belong to organization. In this paper, we propose a simple but effective method for investigating the regularity of entity spans in Chinese NER, dubbed as Regularity-Inspired reCOgnition Network (RICON). Specifically, the proposed model consists of two branches: a regularity-aware module and a regularityagnostic module. The regularity-aware module captures the internal regularity of each span for better entity type prediction, while the regularity-agnostic module is employed to locate the boundary of entities and relieve the excessive attention to span regularity. An orthogonality space is further constructed to encourage two modules to extract different aspects of regularity features. To verify the effectiveness of our method, we conduct extensive experiments on three benchmark datasets and a practical medical dataset. The experimental results show that our RICON significantly outperforms previous state-of-the-art methods, including various lexicon-based methods.
ReCo: Reliable Causal Chain Reasoning via Structural Causal Recurrent Neural NetworksKai Xiong, Xiao Ding, Zhongyang Li et al.
Causal chain reasoning (CCR) is an essential ability for many decision-making AI systems, which requires the model to build reliable causal chains by connecting causal pairs. However, CCR suffers from two main transitive problems: threshold effect and scene drift. In other words, the causal pairs to be spliced may have a conflicting threshold boundary or scenario. To address these issues, we propose a novel Reliable Causal chain reasoning framework~(ReCo), which introduces exogenous variables to represent the threshold and scene factors of each causal pair within the causal chain, and estimates the threshold and scene contradictions across exogenous variables via structural causal recurrent neural networks~(SRNN). Experiments show that ReCo outperforms a series of strong baselines on both Chinese and English CCR datasets. Moreover, by injecting reliable causal chain knowledge distilled by ReCo, BERT can achieve better performances on four downstream causal-related tasks than BERT models enhanced by other kinds of knowledge.
26.4CLJun 11, 2023
AraMUS: Pushing the Limits of Data and Model Scale for Arabic Natural Language ProcessingAsaad Alghamdi, Xinyu Duan, Wei Jiang et al.
Developing monolingual large Pre-trained Language Models (PLMs) is shown to be very successful in handling different tasks in Natural Language Processing (NLP). In this work, we present AraMUS, the largest Arabic PLM with 11B parameters trained on 529GB of high-quality Arabic textual data. AraMUS achieves state-of-the-art performances on a diverse set of Arabic classification and generative tasks. Moreover, AraMUS shows impressive few-shot learning abilities compared with the best existing Arabic PLMs.
6.4LGAug 7, 2024
A Convex-optimization-based Layer-wise Post-training Pruner for Large Language ModelsPengxiang Zhao, Hanyu Hu, Ping Li et al.
Pruning is a critical strategy for compressing trained large language models (LLMs), aiming at substantial memory conservation and computational acceleration without compromising performance. However, existing pruning methods often necessitate inefficient retraining for billion-scale LLMs or rely on heuristic methods such as the optimal brain surgeon framework, which degrade performance. In this paper, we introduce FISTAPruner, the first post-training pruner based on convex optimization models and algorithms. Specifically, we propose a convex optimization model incorporating $\ell_1$ norm to induce sparsity and utilize the FISTA solver for optimization. FISTAPruner incorporates an intra-layer cumulative error correction mechanism and supports parallel pruning. We comprehensively evaluate FISTAPruner on models such as OPT, LLaMA, LLaMA-2, and LLaMA-3 with 125M to 70B parameters under unstructured and 2:4 semi-structured sparsity, demonstrating superior performance over existing state-of-the-art methods across various language benchmarks.
1.4CVJan 10, 2022
Multi-Level Attention for Unsupervised Person Re-IdentificationYi Zheng
The attention mechanism is widely used in deep learning because of its excellent performance in neural networks without introducing additional information. However, in unsupervised person re-identification, the attention module represented by multi-headed self-attention suffers from attention spreading in the condition of non-ground truth. To solve this problem, we design pixel-level attention module to provide constraints for multi-headed self-attention. Meanwhile, for the trait that the identification targets of person re-identification data are all pedestrians in the samples, we design domain-level attention module to provide more comprehensive pedestrian features. We combine head-level, pixel-level and domain-level attention to propose multi-level attention block and validate its performance on for large person re-identification datasets (Market-1501, DukeMTMC-reID and MSMT17 and PersonX).
5.6CVDec 5, 2021
Implicit Neural Deformation for Sparse-View Face ReconstructionMoran Li, Haibin Huang, Yi Zheng et al.
In this work, we present a new method for 3D face reconstruction from sparse-view RGB images. Unlike previous methods which are built upon 3D morphable models (3DMMs) with limited details, we leverage an implicit representation to encode rich geometric features. Our overall pipeline consists of two major components, including a geometry network, which learns a deformable neural signed distance function (SDF) as the 3D face representation, and a rendering network, which learns to render on-surface points of the neural SDF to match the input images via self-supervised optimization. To handle in-the-wild sparse-view input of the same target with different expressions at test time, we propose residual latent code to effectively expand the shape space of the learned implicit face representation as well as a novel view-switch loss to enforce consistency among different views. Our experimental results on several benchmark datasets demonstrate that our approach outperforms alternative baselines and achieves superior face reconstruction results compared to state-of-the-art methods.