Ya Zhang

Yiming Qin, Huangjie Zheng, Jiangchao Yao et al. · apple-ml

Diffusion-based models have shown the merits of generating high-quality visual data while preserving better diversity in recent studies. However, such observation is only justified with curated data distribution, where the data samples are nicely pre-processed to be uniformly distributed in terms of their labels. In practice, a long-tailed data distribution appears more common and how diffusion models perform on such class-imbalanced data remains unknown. In this work, we first investigate this problem and observe significant degradation in both diversity and fidelity when the diffusion model is trained on datasets with class-imbalanced distributions. Especially in tail classes, the generations largely lose diversity and we observe severe mode-collapse issues. To tackle this problem, we set from the hypothesis that the data distribution is not class-balanced, and propose Class-Balancing Diffusion Models (CBDM) that are trained with a distribution adjustment regularizer as a solution. Experiments show that images generated by CBDM exhibit higher diversity and quality in both quantitative and qualitative ways. Our method benchmarked the generation results on CIFAR100/CIFAR100LT dataset and shows outstanding performance on the downstream recognition task.

Xiaoman Zhang, Chaoyi Wu, Ziheng Zhao et al. · harvard

Developing generalist foundation model has recently attracted tremendous attention among researchers in the field of AI for Medicine (AI4Medicine). A pivotal insight in developing these models is their reliance on dataset scaling, which emphasizes the requirements on developing open-source medical image datasets that incorporate diverse supervision signals across various imaging modalities. In this paper, we introduce RadGenome-Chest CT, a comprehensive, large-scale, region-guided 3D chest CT interpretation dataset based on CT-RATE. Specifically, we leverage the latest powerful universal segmentation and large language models, to extend the original datasets (over 25,692 non-contrast 3D chest CT volume and reports from 20,000 patients) from the following aspects: (i) organ-level segmentation masks covering 197 categories, which provide intermediate reasoning visual clues for interpretation; (ii) 665 K multi-granularity grounded reports, where each sentence of the report is linked to the corresponding anatomical region of CT volume in the form of a segmentation mask; (iii) 1.3 M grounded VQA pairs, where questions and answers are all linked with reference segmentation masks, enabling models to associate visual evidence with textual explanations. All grounded reports and VQA pairs in the validation set have gone through manual verification to ensure dataset quality. We believe that RadGenome-Chest CT can significantly advance the development of multimodal medical foundation models, by training to generate texts based on given segmentation regions, which is unattainable with previous relevant datasets. We will release all segmentation masks, grounded reports, and VQA pairs to facilitate further research and development in this field.