Hao Li

Hejun Xiao, Kunyu Peng, Xiangsheng Huang et al.

Fall detection is a vital task in health monitoring, as it allows the system to trigger an alert and therefore enabling faster interventions when a person experiences a fall. Although most previous approaches rely on standard RGB video data, such detailed appearance-aware monitoring poses significant privacy concerns. Depth sensors, on the other hand, are better at preserving privacy as they merely capture the distance of objects from the sensor or camera, omitting color and texture information. In this paper, we introduce a privacy-supporting solution that makes the RGB-trained model applicable in depth domain and utilizes depth data at test time for fall detection. To achieve cross-modal fall detection, we present an unsupervised RGB to Depth (RGB2Depth) cross-modal domain adaptation approach that leverages labelled RGB data and unlabelled depth data during training. Our proposed pipeline incorporates an intermediate domain module for feature bridging, modality adversarial loss for modality discrimination, classification loss for pseudo-labeled depth data and labeled source data, triplet loss that considers both source and target domains, and a novel adaptive loss weight adjustment method for improved coordination among various losses. Our approach achieves state-of-the-art results in the unsupervised RGB2Depth domain adaptation task for fall detection. Code is available at https://github.com/1015206533/privacy_supporting_fall_detection.

Chen Zhang, Yilu An, Ying Chen et al.

Spatial Transcriptomics (ST) merges the benefits of pathology images and gene expression, linking molecular profiles with tissue structure to analyze spot-level function comprehensively. Predicting gene expression from histology images is a cost-effective alternative to expensive ST technologies. However, existing methods mainly focus on spot-level image-to-gene matching but fail to leverage the full hierarchical structure of ST data, especially on the gene expression side, leading to incomplete image-gene alignment. Moreover, a challenge arises from the inherent information asymmetry: gene expression profiles contain more molecular details that may lack salient visual correlates in histological images, demanding a sophisticated representation learning approach to bridge this modality gap. We propose HyperST, a framework for ST prediction that learns multi-level image-gene representations by modeling the data's inherent hierarchy within hyperbolic space, a natural geometric setting for such structures. First, we design a Multi-Level Representation Extractors to capture both spot-level and niche-level representations from each modality, providing context-aware information beyond individual spot-level image-gene pairs. Second, a Hierarchical Hyperbolic Alignment module is introduced to unify these representations, performing spatial alignment while hierarchically structuring image and gene embeddings. This alignment strategy enriches the image representations with molecular semantics, significantly improving cross-modal prediction. HyperST achieves state-of-the-art performance on four public datasets from different tissues, paving the way for more scalable and accurate spatial transcriptomics prediction.