Winning the CVPR'2022 AQTC Challenge: A Two-stage Function-centric ApproachShiwei Wu, Weidong He, Tong Xu et al.
Affordance-centric Question-driven Task Completion for Egocentric Assistant(AQTC) is a novel task which helps AI assistant learn from instructional videos and scripts and guide the user step-by-step. In this paper, we deal with the AQTC via a two-stage Function-centric approach, which consists of Question2Function Module to ground the question with the related function and Function2Answer Module to predict the action based on the historical steps. We evaluated several possible solutions in each module and obtained significant gains compared to the given baselines. Our code is available at \url{https://github.com/starsholic/LOVEU-CVPR22-AQTC}.
2.3BMFeb 9, 2019
Clustering Bioactive Molecules in 3D Chemical Space with Unsupervised Deep LearningChu Qin, Ying Tan, Shang Ying Chen et al.
Unsupervised clustering has broad applications in data stratification, pattern investigation and new discovery beyond existing knowledge. In particular, clustering of bioactive molecules facilitates chemical space mapping, structure-activity studies, and drug discovery. These tasks, conventionally conducted by similarity-based methods, are complicated by data complexity and diversity. We ex-plored the superior learning capability of deep autoencoders for unsupervised clustering of 1.39 mil-lion bioactive molecules into band-clusters in a 3-dimensional latent chemical space. These band-clusters, displayed by a space-navigation simulation software, band molecules of selected bioactivity classes into individual band-clusters possessing unique sets of common sub-structural features beyond structural similarity. These sub-structural features form the frameworks of the literature-reported pharmacophores and privileged fragments. Within each band-cluster, molecules are further banded into selected sub-regions with respect to their bioactivity target, sub-structural features and molecular scaffolds. Our method is potentially applicable for big data clustering tasks of different fields.