Chenyu Li

Danfeng Hong, Bing Zhang, Xuyang Li et al.

The foundation model has recently garnered significant attention due to its potential to revolutionize the field of visual representation learning in a self-supervised manner. While most foundation models are tailored to effectively process RGB images for various visual tasks, there is a noticeable gap in research focused on spectral data, which offers valuable information for scene understanding, especially in remote sensing (RS) applications. To fill this gap, we created for the first time a universal RS foundation model, named SpectralGPT, which is purpose-built to handle spectral RS images using a novel 3D generative pretrained transformer (GPT). Compared to existing foundation models, SpectralGPT 1) accommodates input images with varying sizes, resolutions, time series, and regions in a progressive training fashion, enabling full utilization of extensive RS big data; 2) leverages 3D token generation for spatial-spectral coupling; 3) captures spectrally sequential patterns via multi-target reconstruction; 4) trains on one million spectral RS images, yielding models with over 600 million parameters. Our evaluation highlights significant performance improvements with pretrained SpectralGPT models, signifying substantial potential in advancing spectral RS big data applications within the field of geoscience across four downstream tasks: single/multi-label scene classification, semantic segmentation, and change detection.

Danfeng Hong, Bing Zhang, Hao Li et al.

Artificial intelligence (AI) approaches nowadays have gained remarkable success in single-modality-dominated remote sensing (RS) applications, especially with an emphasis on individual urban environments (e.g., single cities or regions). Yet these AI models tend to meet the performance bottleneck in the case studies across cities or regions, due to the lack of diverse RS information and cutting-edge solutions with high generalization ability. To this end, we build a new set of multimodal remote sensing benchmark datasets (including hyperspectral, multispectral, SAR) for the study purpose of the cross-city semantic segmentation task (called C2Seg dataset), which consists of two cross-city scenes, i.e., Berlin-Augsburg (in Germany) and Beijing-Wuhan (in China). Beyond the single city, we propose a high-resolution domain adaptation network, HighDAN for short, to promote the AI model's generalization ability from the multi-city environments. HighDAN is capable of retaining the spatially topological structure of the studied urban scene well in a parallel high-to-low resolution fusion fashion but also closing the gap derived from enormous differences of RS image representations between different cities by means of adversarial learning. In addition, the Dice loss is considered in HighDAN to alleviate the class imbalance issue caused by factors across cities. Extensive experiments conducted on the C2Seg dataset show the superiority of our HighDAN in terms of segmentation performance and generalization ability, compared to state-of-the-art competitors. The C2Seg dataset and the semantic segmentation toolbox (involving the proposed HighDAN) will be available publicly at https://github.com/danfenghong.

Jing Yao, Danfeng Hong, Chenyu Li et al.

Recurrent neural networks and Transformers have recently dominated most applications in hyperspectral (HS) imaging, owing to their capability to capture long-range dependencies from spectrum sequences. However, despite the success of these sequential architectures, the non-ignorable inefficiency caused by either difficulty in parallelization or computationally prohibitive attention still hinders their practicality, especially for large-scale observation in remote sensing scenarios. To address this issue, we herein propose SpectralMamba -- a novel state space model incorporated efficient deep learning framework for HS image classification. SpectralMamba features the simplified but adequate modeling of HS data dynamics at two levels. First, in spatial-spectral space, a dynamical mask is learned by efficient convolutions to simultaneously encode spatial regularity and spectral peculiarity, thus attenuating the spectral variability and confusion in discriminative representation learning. Second, the merged spectrum can then be efficiently operated in the hidden state space with all parameters learned input-dependent, yielding selectively focused responses without reliance on redundant attention or imparallelizable recurrence. To explore the room for further computational downsizing, a piece-wise scanning mechanism is employed in-between, transferring approximately continuous spectrum into sequences with squeezed length while maintaining short- and long-term contextual profiles among hundreds of bands. Through extensive experiments on four benchmark HS datasets acquired by satellite-, aircraft-, and UAV-borne imagers, SpectralMamba surprisingly creates promising win-wins from both performance and efficiency perspectives.

Lei Ding, Danfeng Hong, Maofan Zhao et al.

In the last decade, the rapid development of deep learning (DL) has made it possible to perform automatic, accurate, and robust Change Detection (CD) on large volumes of Remote Sensing Images (RSIs). However, despite advances in CD methods, their practical application in real-world contexts remains limited due to the diverse input data and the applicational context. For example, the collected RSIs can be time-series observations, and more informative results are required to indicate the time of change or the specific change category. Moreover, training a Deep Neural Network (DNN) requires a massive amount of training samples, whereas in many cases these samples are difficult to collect. To address these challenges, various specific CD methods have been developed considering different application scenarios and training resources. Additionally, recent advancements in image generation, self-supervision, and visual foundation models (VFMs) have opened up new approaches to address the 'data-hungry' issue of DL-based CD. The development of these methods in broader application scenarios requires further investigation and discussion. Therefore, this article summarizes the literature methods for different CD tasks and the available strategies and techniques to train and deploy DL-based CD methods in sample-limited scenarios. We expect that this survey can provide new insights and inspiration for researchers in this field to develop more effective CD methods that can be applied in a wider range of contexts.

Chenyu Li, Bing Zhang, Danfeng Hong et al.

Current hyperspectral anomaly detection (HAD) benchmark datasets suffer from low resolution, simple background, and small size of the detection data. These factors also limit the performance of the well-known low-rank representation (LRR) models in terms of robustness on the separation of background and target features and the reliance on manual parameter selection. To this end, we build a new set of HAD benchmark datasets for improving the robustness of the HAD algorithm in complex scenarios, AIR-HAD for short. Accordingly, we propose a generalized and interpretable HAD network by deeply unfolding a dictionary-learnable LLR model, named LRR-Net$^+$, which is capable of spectrally decoupling the background structure and object properties in a more generalized fashion and eliminating the bias introduced by vital interference targets concurrently. In addition, LRR-Net$^+$ integrates the solution process of the Alternating Direction Method of Multipliers (ADMM) optimizer with the deep network, guiding its search process and imparting a level of interpretability to parameter optimization. Additionally, the integration of physical models with DL techniques eliminates the need for manual parameter tuning. The manually tuned parameters are seamlessly transformed into trainable parameters for deep neural networks, facilitating a more efficient and automated optimization process. Extensive experiments conducted on the AIR-HAD dataset show the superiority of our LRR-Net$^+$ in terms of detection performance and generalization ability, compared to top-performing rivals. Furthermore, the compilable codes and our AIR-HAD benchmark datasets in this paper will be made available freely and openly at \url{https://sites.google.com/view/danfeng-hong}.

Xizhi Wu, Madeline S. Kreider, Philip E. Empey et al.

Objective: Fluoropyrimidines are widely prescribed for colorectal and breast cancers, but are associated with toxicities such as hand-foot syndrome and cardiotoxicity. Since toxicity documentation is often embedded in clinical notes, we aimed to develop and evaluate natural language processing (NLP) methods to extract treatment and toxicity information. Materials and Methods: We constructed a gold-standard dataset of 236 clinical notes from 204,165 adult oncology patients. Domain experts annotated categories related to treatment regimens and toxicities. We developed rule-based, machine learning-based (Random Forest, Support Vector Machine [SVM], Logistic Regression [LR]), deep learning-based (BERT, ClinicalBERT), and large language models (LLM)-based NLP approaches (zero-shot and error-analysis prompting). Models used an 80:20 train-test split. Results: Sufficient data existed to train and evaluate 5 annotated categories. Error-analysis prompting achieved optimal precision, recall, and F1 scores (F1=1.000) for treatment and toxicities extraction, whereas zero-shot prompting reached F1=1.000 for treatment and F1=0.876 for toxicities extraction.LR and SVM ranked second for toxicities (F1=0.937). Deep learning underperformed, with BERT (F1=0.873 treatment; F1= 0.839 toxicities) and ClinicalBERT (F1=0.873 treatment; F1 = 0.886 toxicities). Rule-based methods served as our baseline with F1 scores of 0.857 in treatment and 0.858 in toxicities. Discussion: LMM-based approaches outperformed all others, followed by machine learning methods. Machine and deep learning approaches were limited by small training data and showed limited generalizability, particularly for rare categories. Conclusion: LLM-based NLP most effectively extracted fluoropyrimidine treatment and toxicity information from clinical notes, and has strong potential to support oncology research and pharmacovigilance.

Danfeng Hong, Chenyu Li, Naoto Yokoya et al.

Hyperspectral imaging (HSI) is an advanced sensing modality that simultaneously captures spatial and spectral information, enabling non-invasive, label-free analysis of material, chemical, and biological properties. This Primer presents a comprehensive overview of HSI, from the underlying physical principles and sensor architectures to key steps in data acquisition, calibration, and correction. We summarize common data structures and highlight classical and modern analysis methods, including dimensionality reduction, classification, spectral unmixing, and AI-driven techniques such as deep learning. Representative applications across Earth observation, precision agriculture, biomedicine, industrial inspection, cultural heritage, and security are also discussed, emphasizing HSI's ability to uncover sub-visual features for advanced monitoring, diagnostics, and decision-making. Persistent challenges, such as hardware trade-offs, acquisition variability, and the complexity of high-dimensional data, are examined alongside emerging solutions, including computational imaging, physics-informed modeling, cross-modal fusion, and self-supervised learning. Best practices for dataset sharing, reproducibility, and metadata documentation are further highlighted to support transparency and reuse. Looking ahead, we explore future directions toward scalable, real-time, and embedded HSI systems, driven by sensor miniaturization, self-supervised learning, and foundation models. As HSI evolves into a general-purpose, cross-disciplinary platform, it holds promise for transformative applications in science, technology, and society.