Yufeng Li

Xu Yan, Weimin Wang, MingXuan Xiao et al.

Gastric cancer and Colon adenocarcinoma represent widespread and challenging malignancies with high mortality rates and complex treatment landscapes. In response to the critical need for accurate prognosis in cancer patients, the medical community has embraced the 5-year survival rate as a vital metric for estimating patient outcomes. This study introduces a pioneering approach to enhance survival prediction models for gastric and Colon adenocarcinoma patients. Leveraging advanced image analysis techniques, we sliced whole slide images (WSI) of these cancers, extracting comprehensive features to capture nuanced tumor characteristics. Subsequently, we constructed patient-level graphs, encapsulating intricate spatial relationships within tumor tissues. These graphs served as inputs for a sophisticated 4-layer graph convolutional neural network (GCN), designed to exploit the inherent connectivity of the data for comprehensive analysis and prediction. By integrating patients' total survival time and survival status, we computed C-index values for gastric cancer and Colon adenocarcinoma, yielding 0.57 and 0.64, respectively. Significantly surpassing previous convolutional neural network models, these results underscore the efficacy of our approach in accurately predicting patient survival outcomes. This research holds profound implications for both the medical and AI communities, offering insights into cancer biology and progression while advancing personalized treatment strategies. Ultimately, our study represents a significant stride in leveraging AI-driven methodologies to revolutionize cancer prognosis and improve patient outcomes on a global scale.

Jie-Jing Shao, Bo-Wen Zhang, Xiao-Wen Yang et al.

Recent advances in LLMs, particularly in language reasoning and tool integration, have rapidly sparked the \emph{Language Agents} for real-world development. Among these, travel planning represents a prominent domain, combining complex multi-objective planning challenges with practical deployment demands. However, existing benchmarks often oversimplify real-world requirements by focusing on synthetic queries and limited constraints. We address the gap of evaluating language agents in multi-day, multi-POI travel planning scenarios with diverse and open human needs. Specifically, we introduce \emph{ChinaTravel}, the first open-ended benchmark grounded in authentic Chinese travel requirements collected from 1,154 human participants. We design a compositionally generalizable domain-specific language (DSL) for scalable evaluation, covering feasibility, constraint satisfaction, and preference comparison. Empirical studies reveal the potential of neuro-symbolic agents in travel planning, achieving a 37.0\% constraint satisfaction rate on human queries, a 10\times improvement over purely neural models. These findings highlight ChinaTravel as a pivotal milestone for advancing language agents in complex, real-world planning scenarios.

Zhi Zhou, Ming Yang, Jiang-Xin Shi et al.

Vision-language models (VLMs), such as CLIP, have demonstrated impressive zero-shot capabilities for various downstream tasks. Their performance can be further enhanced through few-shot prompt tuning methods. However, current studies evaluate the performance of learned prompts separately on base and new classes. This evaluation lacks practicality for real-world applications since downstream tasks cannot determine whether the data belongs to base or new classes in advance. In this paper, we explore a problem setting called Open-world Prompt Tuning (OPT), which involves tuning prompts on base classes and evaluating on a combination of base and new classes. By introducing Decomposed Prompt Tuning framework (DePT), we theoretically demonstrate that OPT can be solved by incorporating out-of-distribution detection into prompt tuning, thereby enhancing the base-to-new discriminability. Based on DePT, we present a novel prompt tuning approach, namely, Decomposed Context Optimization (DeCoOp), which introduces new-class detectors and sub-classifiers to further enhance the base-class and new-class discriminability. Experimental results on 11 benchmark datasets validate the effectiveness of DePT and demonstrate that DeCoOp outperforms current state-of-the-art methods, providing a significant 2% average accuracy improvement.