K M Arefeen Sultan

K M Arefeen Sultan, Md Hasibul Husain Hisham, Benjamin Orkild et al.

The accurate evaluation of left atrial fibrosis via high-quality 3D Late Gadolinium Enhancement (LGE) MRI is crucial for atrial fibrillation management but is hindered by factors like patient movement and imaging variability. The pursuit of automated LGE MRI quality assessment is critical for enhancing diagnostic accuracy, standardizing evaluations, and improving patient outcomes. The deep learning models aimed at automating this process face significant challenges due to the scarcity of expert annotations, high computational costs, and the need to capture subtle diagnostic details in highly variable images. This study introduces HAMIL-QA, a multiple instance learning (MIL) framework, designed to overcome these obstacles. HAMIL-QA employs a hierarchical bag and sub-bag structure that allows for targeted analysis within sub-bags and aggregates insights at the volume level. This hierarchical MIL approach reduces reliance on extensive annotations, lessens computational load, and ensures clinically relevant quality predictions by focusing on diagnostically critical image features. Our experiments show that HAMIL-QA surpasses existing MIL methods and traditional supervised approaches in accuracy, AUROC, and F1-Score on an LGE MRI scan dataset, demonstrating its potential as a scalable solution for LGE MRI quality assessment automation. The code is available at: $\href{https://github.com/arf111/HAMIL-QA}{\text{this https URL}}$

K M Arefeen Sultan, Benjamin Orkild, Alan Morris et al.

Accurate assessment of left atrial fibrosis in patients with atrial fibrillation relies on high-quality 3D late gadolinium enhancement (LGE) MRI images. However, obtaining such images is challenging due to patient motion, changing breathing patterns, or sub-optimal choice of pulse sequence parameters. Automated assessment of LGE-MRI image diagnostic quality is clinically significant as it would enhance diagnostic accuracy, improve efficiency, ensure standardization, and contributes to better patient outcomes by providing reliable and high-quality LGE-MRI scans for fibrosis quantification and treatment planning. To address this, we propose a two-stage deep-learning approach for automated LGE-MRI image diagnostic quality assessment. The method includes a left atrium detector to focus on relevant regions and a deep network to evaluate diagnostic quality. We explore two training strategies, multi-task learning, and pretraining using contrastive learning, to overcome limited annotated data in medical imaging. Contrastive Learning result shows about $4\%$, and $9\%$ improvement in F1-Score and Specificity compared to Multi-Task learning when there's limited data.

K M Arefeen Sultan, Kaysen Hansen, Benjamin Orkild et al.

High-quality Late Gadolinium Enhancement (LGE) MRI can be helpful for atrial fibrillation management, yet scan quality is frequently compromised by patient motion, irregular breathing, and suboptimal image acquisition timing. While Multiple Instance Learning (MIL) has emerged as a powerful tool for automated quality assessment under weak supervision, current state-of-the-art methods map localized visual evidence to a single, opaque global feature vector. This black box approach fails to provide actionable feedback on specific failure modes, obscuring whether a scan degrades due to motion blur, inadequate contrast, or a lack of anatomical context. In this paper, we propose Adversarial Concept-MIL (AC-MIL), a weakly supervised framework that decomposes global image quality into clinically defined radiological concepts using only volume-level supervision. To capture latent quality variations without entangling predefined concepts, our framework incorporates an unsupervised residual branch guided by an adversarial erasure mechanism to strictly prevent information leakage. Furthermore, we introduce a spatial diversity constraint that penalizes overlap between distinct concept attention maps, ensuring localized and interpretable feature extraction. Extensive experiments on a clinical dataset of atrial LGE-MRI volumes demonstrate that AC-MIL successfully opens the MIL black box, providing highly localized spatial concept maps that allow clinicians to pinpoint the specific causes of non-diagnostic scans. Crucially, our framework achieves this deep clinical transparency while maintaining highly competitive ordinal grading performance against existing baselines. Code to be released on acceptance.

Nafisa Binte Feroz, Chandrima Sarker, Tanzima Ahsan et al.

One of the most urgent problems is the overcrowding in emergency departments (EDs), caused by an aging population and rising healthcare costs. Patient dispositions have become more complex as a result of the strain on hospital infrastructure and the scarcity of medical resources. Individuals with more dangerous health issues should be prioritized in the emergency room. Thus, our research aims to develop a prediction model for patient disposition using EF-Net. This model will incorporate categorical features into the neural network layer and add numerical features with the embedded categorical features. We combine the EF-Net and XGBoost models to attain higher accuracy in our results. The result is generated using the soft voting technique. In EF-Net, we attained an accuracy of 95.33%, whereas in the Ensemble Model, we achieved an accuracy of 96%. The experiment's analysis shows that EF-Net surpasses existing works in accuracy, AUROC, and F1-Score on the MIMIC-IV-ED dataset, demonstrating its potential as a scalable solution for patient disposition assessment. Our code is available at https://github.com/nafisa67/thesis

K M Arefeen Sultan, Labiba Kanij Rupty, Nahidul Islam Pranto et al.

We propose a method to translate cartoon images to real world images using Generative Aderserial Network (GAN). Existing GAN-based image-to-image translation methods which are trained on paired datasets are impractical as the data is difficult to accumulate. Therefore, in this paper we exploit the Cycle-Consistent Adversarial Networks (CycleGAN) method for images translation which needs an unpaired dataset. By applying CycleGAN we show that our model is able to generate meaningful real world images from cartoon images. However, we implement another state of the art technique $-$ Deep Analogy $-$ to compare the performance of our approach.