Tao Zhang

Tao Zhang, Chenglin Zhu, Yanjun Shen et al.

The adeptness of Large Language Models (LLMs) in comprehending and following natural language instructions is critical for their deployment in sophisticated real-world applications. Existing evaluations mainly focus on fragmented constraints or narrow scenarios, but they overlook the comprehensiveness and authenticity of constraints from the user's perspective. To bridge this gap, we propose CFBench, a large-scale Comprehensive Constraints Following Benchmark for LLMs, featuring 1,000 curated samples that cover more than 200 real-life scenarios and over 50 NLP tasks. CFBench meticulously compiles constraints from real-world instructions and constructs an innovative systematic framework for constraint types, which includes 10 primary categories and over 25 subcategories, and ensures each constraint is seamlessly integrated within the instructions. To make certain that the evaluation of LLM outputs aligns with user perceptions, we propose an advanced methodology that integrates multi-dimensional assessment criteria with requirement prioritization, covering various perspectives of constraints, instructions, and requirement fulfillment. Evaluating current leading LLMs on CFBench reveals substantial room for improvement in constraints following, and we further investigate influencing factors and enhancement strategies. The data and code are publicly available at https://github.com/PKU-Baichuan-MLSystemLab/CFBench

Tao Zhang, Xingye Tian, Yikang Zhou et al.

We present the \textbf{D}ecoupled \textbf{VI}deo \textbf{S}egmentation (DVIS) framework, a novel approach for the challenging task of universal video segmentation, including video instance segmentation (VIS), video semantic segmentation (VSS), and video panoptic segmentation (VPS). Unlike previous methods that model video segmentation in an end-to-end manner, our approach decouples video segmentation into three cascaded sub-tasks: segmentation, tracking, and refinement. This decoupling design allows for simpler and more effective modeling of the spatio-temporal representations of objects, especially in complex scenes and long videos. Accordingly, we introduce two novel components: the referring tracker and the temporal refiner. These components track objects frame by frame and model spatio-temporal representations based on pre-aligned features. To improve the tracking capability of DVIS, we propose a denoising training strategy and introduce contrastive learning, resulting in a more robust framework named DVIS++. Furthermore, we evaluate DVIS++ in various settings, including open vocabulary and using a frozen pre-trained backbone. By integrating CLIP with DVIS++, we present OV-DVIS++, the first open-vocabulary universal video segmentation framework. We conduct extensive experiments on six mainstream benchmarks, including the VIS, VSS, and VPS datasets. Using a unified architecture, DVIS++ significantly outperforms state-of-the-art specialized methods on these benchmarks in both close- and open-vocabulary settings. Code:~\url{https://github.com/zhang-tao-whu/DVIS_Plus}.

Tao Zhang, Haobo Yuan, Lu Qi et al.

Recently, state space models have exhibited strong global modeling capabilities and linear computational complexity in contrast to transformers. This research focuses on applying such architecture to more efficiently and effectively model point cloud data globally with linear computational complexity. In particular, for the first time, we demonstrate that Mamba-based point cloud methods can outperform previous methods based on transformer or multi-layer perceptrons (MLPs). To enable Mamba to process 3-D point cloud data more effectively, we propose a novel Consistent Traverse Serialization method to convert point clouds into 1-D point sequences while ensuring that neighboring points in the sequence are also spatially adjacent. Consistent Traverse Serialization yields six variants by permuting the order of \textit{x}, \textit{y}, and \textit{z} coordinates, and the synergistic use of these variants aids Mamba in comprehensively observing point cloud data. Furthermore, to assist Mamba in handling point sequences with different orders more effectively, we introduce point prompts to inform Mamba of the sequence's arrangement rules. Finally, we propose positional encoding based on spatial coordinate mapping to inject positional information into point cloud sequences more effectively. Point Cloud Mamba surpasses the state-of-the-art (SOTA) point-based method PointNeXt and achieves new SOTA performance on the ScanObjectNN, ModelNet40, ShapeNetPart, and S3DIS datasets. It is worth mentioning that when using a more powerful local feature extraction module, our PCM achieves 79.6 mIoU on S3DIS, significantly surpassing the previous SOTA models, DeLA and PTv3, by 5.5 mIoU and 4.9 mIoU, respectively.

Runtian Yuan, Mohan Chen, Jilan Xu et al.

Referring Medical Image Sequence Segmentation (Ref-MISS) is a novel and challenging task that aims to segment anatomical structures in medical image sequences (\emph{e.g.} endoscopy, ultrasound, CT, and MRI) based on natural language descriptions. This task holds significant clinical potential and offers a user-friendly advancement in medical imaging interpretation. Existing 2D and 3D segmentation models struggle to explicitly track objects of interest across medical image sequences, and lack support for nteractive, text-driven guidance. To address these limitations, we propose Text-Promptable Propagation (TPP), a model designed for referring medical image sequence segmentation. TPP captures the intrinsic relationships among sequential images along with their associated textual descriptions. Specifically, it enables the recognition of referred objects through cross-modal referring interaction, and maintains continuous tracking across the sequence via Transformer-based triple propagation, using text embeddings as queries. To support this task, we curate a large-scale benchmark, Ref-MISS-Bench, which covers 4 imaging modalities and 20 different organs and lesions. Experimental results on this benchmark demonstrate that TPP consistently outperforms state-of-the-art methods in both medical segmentation and referring video object segmentation.

Yigang Chen, Xiang Ji, Ziyue Zhang et al.

Deep learning-based drug-target interaction (DTI) prediction methods have demonstrated strong performance; however, real-world applicability remains constrained by limited data diversity and modeling complexity. To address these challenges, we propose SCOPE-DTI, a unified framework combining a large-scale, balanced semi-inductive human DTI dataset with advanced deep learning modeling. Constructed from 13 public repositories, the SCOPE dataset expands data volume by up to 100-fold compared to common benchmarks such as the Human dataset. The SCOPE model integrates three-dimensional protein and compound representations, graph neural networks, and bilinear attention mechanisms to effectively capture cross domain interaction patterns, significantly outperforming state-of-the-art methods across various DTI prediction tasks. Additionally, SCOPE-DTI provides a user-friendly interface and database. We further validate its effectiveness by experimentally identifying anticancer targets of Ginsenoside Rh1. By offering comprehensive data, advanced modeling, and accessible tools, SCOPE-DTI accelerates drug discovery research.

Hao Fang, Hao Yu, Sihao Teng et al.

Unsupervised learning methods, such as Deep Image Prior (DIP), have shown great potential in tomographic imaging due to their training-data-free nature and high generalization capability. However, their reliance on numerous network parameter iterations results in high computational costs, limiting their practical application, particularly in complex 3D or time-sequence tomographic imaging tasks. To overcome these challenges, we propose Deep Dynamic Image Prior (D2IP), a novel framework for 3D time-sequence imaging. D2IP introduces three key strategies - Unsupervised Parameter Warm-Start (UPWS), Temporal Parameter Propagation (TPP), and a customized lightweight reconstruction backbone, 3D-FastResUNet - to accelerate convergence, enforce temporal coherence, and improve computational efficiency. Experimental results on both simulated and clinical pulmonary datasets demonstrate that D2IP enables fast and accurate 3D time-sequence Electrical Impedance Tomography (tsEIT) reconstruction. Compared to state-of-the-art baselines, D2IP delivers superior image quality, with a 24.8% increase in average MSSIM and an 8.1% reduction in ERR, alongside significantly reduced computational time (7.1x faster), highlighting its promise for clinical dynamic pulmonary imaging.

Shaohua Wan, Zhijun Chen, Tao Zhang et al.

Recently significant performance improvement in face detection was made possible by deeply trained convolutional networks. In this report, a novel approach for training state-of-the-art face detector is described. The key is to exploit the idea of hard negative mining and iteratively update the Faster R-CNN based face detector with the hard negatives harvested from a large set of background examples. We demonstrate that our face detector outperforms state-of-the-art detectors on the FDDB dataset, which is the de facto standard for evaluating face detection algorithms.