Jiaxin Liu

Tian Lan, Lei Xu, Zimu Yuan et al.

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must identify multiple potential abnormalities within complex anatomical structures across different imaging planes, a process that requires significant expertise and is prone to variability. We developed OrthoDiffusion, a unified diffusion-based foundation model designed for multi-task musculoskeletal MRI interpretation. The framework utilizes three orientation-specific 3D diffusion models, pre-trained in a self-supervised manner on 15,948 unlabeled knee MRI scans, to learn robust anatomical features from sagittal, coronal, and axial views. These view-specific representations are integrated to support diverse clinical tasks, including anatomical segmentation and multi-label diagnosis. Our evaluation demonstrates that OrthoDiffusion achieves excellent performance in the segmentation of 11 knee structures and the detection of 8 knee abnormalities. The model exhibited remarkable robustness across different clinical centers and MRI field strengths, consistently outperforming traditional supervised models. Notably, in settings where labeled data was scarce, OrthoDiffusion maintained high diagnostic precision using only 10\% of training labels. Furthermore, the anatomical representations learned from knee imaging proved highly transferable to other joints, achieving strong diagnostic performance across 11 diseases of the ankle and shoulder. These findings suggest that diffusion-based foundation models can serve as a unified platform for multi-disease diagnosis and anatomical segmentation, potentially improving the efficiency and accuracy of musculoskeletal MRI interpretation in real-world clinical workflows.

Xiaoxiang Wang, Jiaxin Liu, Miaojie Feng et al.

3D Multi-Object Tracking (MOT), a fundamental component of environmental perception, is essential for intelligent systems like autonomous driving and robotic sensing. Although Tracking-by-Detection frameworks have demonstrated excellent performance in recent years, their application in real-world scenarios faces significant challenges. Object movement in complex environments is often highly nonlinear, while existing methods typically rely on linear approximations of motion. Furthermore, system noise is frequently modeled as a Gaussian distribution, which fails to capture the true complexity of the noise dynamics. These oversimplified modeling assumptions can lead to significant reductions in tracking precision. To address this, we propose a GRU-based MOT method, which introduces a learnable Kalman filter into the motion module. This approach is able to learn object motion characteristics through data-driven learning, thereby avoiding the need for manual model design and model error. At the same time, to avoid abnormal supervision caused by the wrong association between annotations and trajectories, we design a semi-supervised learning strategy to accelerate the convergence speed and improve the robustness of the model. Evaluation experiment on the nuScenes and Argoverse2 datasets demonstrates that our system exhibits superior performance and significant potential compared to traditional TBD methods.