Ying Zhang

Ammar Alsheghri, Farnoosh Ghadiri, Ying Zhang et al.

Teeth segmentation is an important topic in dental restorations that is essential for crown generation, diagnosis, and treatment planning. In the dental field, the variability of input data is high and there are no publicly available 3D dental arch datasets. Although there has been improvement in the field provided by recent deep learning architectures on 3D data, there still exists some problems such as properly identifying missing teeth in an arch. We propose to use spectral clustering as a self-supervisory signal to joint-train neural networks for segmentation of 3D arches. Our approach is motivated by the observation that K-means clustering provides cues to capture margin lines related to human perception. The main idea is to automatically generate training data by decomposing unlabeled 3D arches into segments relying solely on geometric information. The network is then trained using a joint loss that combines a supervised loss of annotated input and a self-supervised loss of non-labeled input. Our collected data has a variety of arches including arches with missing teeth. Our experimental results show improvement over the fully supervised state-of-the-art MeshSegNet when using semi-supervised learning. Finally, we contribute code and a dataset.

Cheng Peng, Xi Yang, Aokun Chen et al.

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using 277 billion words of mixed clinical and English text with a GPT-3 architecture of 20 billion parameters. GatorTronGPT improves biomedical natural language processing for medical research. Synthetic NLP models trained using GatorTronGPT generated text outperform NLP models trained using real-world clinical text. Physicians Turing test using 1 (worst) to 9 (best) scale shows that there is no significant difference in linguistic readability (p = 0.22; 6.57 of GatorTronGPT compared with 6.93 of human) and clinical relevance (p = 0.91; 7.0 of GatorTronGPT compared with 6.97 of human) and that physicians cannot differentiate them (p < 0.001). This study provides insights on the opportunities and challenges of LLMs for medical research and healthcare.

Xiangyu Meng, Xudong Zhang, Gan Wang et al.

Liver cancer is one of the most common malignant diseases in the world. Segmentation and labeling of liver tumors and blood vessels in CT images can provide convenience for doctors in liver tumor diagnosis and surgical intervention. In the past decades, many state-of-the-art medical image segmentation algorithms appeared during this period. With the development of embedded devices, embedded deployment for medical segmentation and automatic reconstruction brings prospects for future automated surgical tasks. Yet, most of the existing segmentation methods mostly care about the spatial feature context and have a perception defect in the semantic relevance of medical images, which significantly affects the segmentation accuracy of liver tumors and blood vessels. Deploying large and complex models into embedded devices requires a reasonable trade-off between model accuracy, reasoning speed and model capacity. Given these problems, we introduce a multi-scale feature fusion network called TransFusionNet based on Transformer. This network achieved very competitive performance for liver vessel and liver tumor segmentation tasks, meanwhile it can improve the recognition of morphologic margins of liver tumors by exploiting the global information of CT images. Experiments show that in vessel segmentation task TransFusionNet achieved mean Dice coefficients of 0.899 and in liver tumor segmentation task TransFusionNet achieved mean Dice coefficients of 0.961. Compared with the state-of-the-art framework, our model achieves the best segmentation result. In addition, we deployed the model into an embedded micro-structure and constructed an integrated model for liver tumor vascular segmentation and reconstruction. This proprietary structure will be the exclusive component of the future medical field.