Yuan Liang

Jiawei Yang, Yuan Liang, Yao Zhang et al.

The ability of deep learning to predict with uncertainty is recognized as key for its adoption in clinical routines. Moreover, performance gain has been enabled by modelling uncertainty according to empirical evidence. While previous work has widely discussed the uncertainty estimation in segmentation and classification tasks, its application on bounding-box-based detection has been limited, mainly due to the challenge of bounding box aligning. In this work, we explore to augment a 2.5D detection CNN with two different bounding-box-level (or instance-level) uncertainty estimates, i.e., predictive variance and Monte Carlo (MC) sample variance. Experiments are conducted for lung nodule detection on LUNA16 dataset, a task where significant semantic ambiguities can exist between nodules and non-nodules. Results show that our method improves the evaluating score from 84.57% to 88.86% by utilizing a combination of both types of variances. Moreover, we show the generated uncertainty enables superior operating points compared to using the probability threshold only, and can further boost the performance to 89.52%. Example nodule detections are visualized to further illustrate the advantages of our method.

Liang Qiu, Yizhou Zhao, Weiyan Shi et al.

Inducing a meaningful structural representation from one or a set of dialogues is a crucial but challenging task in computational linguistics. Advancement made in this area is critical for dialogue system design and discourse analysis. It can also be extended to solve grammatical inference. In this work, we propose to incorporate structured attention layers into a Variational Recurrent Neural Network (VRNN) model with discrete latent states to learn dialogue structure in an unsupervised fashion. Compared to a vanilla VRNN, structured attention enables a model to focus on different parts of the source sentence embeddings while enforcing a structural inductive bias. Experiments show that on two-party dialogue datasets, VRNN with structured attention learns semantic structures that are similar to templates used to generate this dialogue corpus. While on multi-party dialogue datasets, our model learns an interactive structure demonstrating its capability of distinguishing speakers or addresses, automatically disentangling dialogues without explicit human annotation.

Hongyan Gu, Yuan Liang, Yifan Xu et al.

Recent developments in AI have provided assisting tools to support pathologists' diagnoses. However, it remains challenging to incorporate such tools into pathologists' practice; one main concern is AI's insufficient workflow integration with medical decisions. We observed pathologists' examination and discovered that the main hindering factor to integrate AI is its incompatibility with pathologists' workflow. To bridge the gap between pathologists and AI, we developed a human-AI collaborative diagnosis tool -- xPath -- that shares a similar examination process to that of pathologists, which can improve AI's integration into their routine examination. The viability of xPath is confirmed by a technical evaluation and work sessions with twelve medical professionals in pathology. This work identifies and addresses the challenge of incorporating AI models into pathology, which can offer first-hand knowledge about how HCI researchers can work with medical professionals side-by-side to bring technological advances to medical tasks towards practical applications.

Yuan Liang, Hsuan-Wei Fan, Zhujun Fang et al.

Due to a lack of medical resources or oral health awareness, oral diseases are often left unexamined and untreated, affecting a large population worldwide. With the advent of low-cost, sensor-equipped smartphones, mobile apps offer a promising possibility for promoting oral health. However, to the best of our knowledge, no mobile health (mHealth) solutions can directly support a user to self-examine their oral health condition. This paper presents OralCam, the first interactive app that enables end-users' self-examination of five common oral conditions (diseases or early disease signals) by taking smartphone photos of one's oral cavity. OralCam allows a user to annotate additional information (e.g. living habits, pain, and bleeding) to augment the input image, and presents the output hierarchically, probabilistically and with visual explanations to help a laymen user understand examination results. Developed on our in-house dataset that consists of 3,182 oral photos annotated by dental experts, our deep learning based framework achieved an average detection sensitivity of 0.787 over five conditions with high localization accuracy. In a week-long in-the-wild user study (N=18), most participants had no trouble using OralCam and interpreting the examination results. Two expert interviews further validate the feasibility of OralCam for promoting users' awareness of oral health.

Yuan Liang, Weinan Song, J. P. Dym et al.

Label propagation is a popular technique for anatomical segmentation. In this work, we propose a novel deep framework for label propagation based on non-local label fusion. Our framework, named CompareNet, incorporates subnets for both extracting discriminating features, and learning the similarity measure, which lead to accurate segmentation. We also introduce the voxel-wise classification as an unary potential to the label fusion function, for alleviating the search failure issue of the existing non-local fusion strategies. Moreover, CompareNet is end-to-end trainable, and all the parameters are learnt together for the optimal performance. By evaluating CompareNet on two public datasets IBSRv2 and MICCAI 2012 for brain segmentation, we show it outperforms state-of-the-art methods in accuracy, while being robust to pathologies.