Wen Wang

Weixiang Yan, Haitian Liu, Tengxiao Wu et al.

LLMs have achieved significant performance progress in various NLP applications. However, LLMs still struggle to meet the strict requirements for accuracy and reliability in the medical field and face many challenges in clinical applications. Existing clinical diagnostic evaluation benchmarks for evaluating medical agents powered by LLMs have severe limitations. Firstly, most existing medical evaluation benchmarks face the risk of data leakage or contamination. Secondly, existing benchmarks often neglect the characteristics of multiple departments and specializations in modern medical practice. Thirdly, existing evaluation methods are limited to multiple-choice questions, which do not align with the real-world diagnostic scenarios. Lastly, existing evaluation methods lack comprehensive evaluations of end-to-end real clinical scenarios. These limitations in benchmarks in turn obstruct advancements of LLMs and agents for medicine. To address these limitations, we introduce ClinicalLab, a comprehensive clinical diagnosis agent alignment suite. ClinicalLab includes ClinicalBench, an end-to-end multi-departmental clinical diagnostic evaluation benchmark for evaluating medical agents and LLMs. ClinicalBench is based on real cases that cover 24 departments and 150 diseases. ClinicalLab also includes four novel metrics (ClinicalMetrics) for evaluating the effectiveness of LLMs in clinical diagnostic tasks. We evaluate 17 LLMs and find that their performance varies significantly across different departments. Based on these findings, in ClinicalLab, we propose ClinicalAgent, an end-to-end clinical agent that aligns with real-world clinical diagnostic practices. We systematically investigate the performance and applicable scenarios of variants of ClinicalAgent on ClinicalBench. Our findings demonstrate the importance of aligning with modern medical practices in designing medical agents.

Wen Wang, Wei Zhang, Shukai Liu et al.

Session-based target behavior prediction aims to predict the next item to be interacted with specific behavior types (e.g., clicking). Although existing methods for session-based behavior prediction leverage powerful representation learning approaches to encode items' sequential relevance in a low-dimensional space, they suffer from several limitations. Firstly, they focus on only utilizing the same type of user behavior for prediction, but ignore the potential of taking other behavior data as auxiliary information. This is particularly crucial when the target behavior is sparse but important (e.g., buying or sharing an item). Secondly, item-to-item relations are modeled separately and locally in one behavior sequence, and they lack a principled way to globally encode these relations more effectively. To overcome these limitations, we propose a novel Multi-relational Graph Neural Network model for Session-based target behavior Prediction, namely MGNN-SPred for short. Specifically, we build a Multi-Relational Item Graph (MRIG) based on all behavior sequences from all sessions, involving target and auxiliary behavior types. Based on MRIG, MGNN-SPred learns global item-to-item relations and further obtains user preferences w.r.t. current target and auxiliary behavior sequences, respectively. In the end, MGNN-SPred leverages a gating mechanism to adaptively fuse user representations for predicting next item interacted with target behavior. The extensive experiments on two real-world datasets demonstrate the superiority of MGNN-SPred by comparing with state-of-the-art session-based prediction methods, validating the benefits of leveraging auxiliary behavior and learning item-to-item relations over MRIG.