Cheng Li

Baomin Wang, Geng Hu, Dan Chen et al.

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the limitation of staining quality and diversity of morphology features in BC microscopy whole slide images (WSIs), traditional image processing approaches are helpless. To overcome this challenge, we propose a two-stage detection method inspired by the structure prior of BC based on deep learning, which cascades to implement BCs coarse detection at the WSI-level and fine-grained classification in patch-level. The coarse detection network is a multi-task detection framework based on circular bounding boxes for cells detection, and central key points for nucleus detection. The circle representation reduces the degrees of freedom, mitigates the effect of surrounding impurities compared to usual rectangular boxes and can be rotation invariant in WSI. Detecting key points in the nucleus can assist network perception and be used for unsupervised color layer segmentation in later fine-grained classification. The fine classification network consists of a background region suppression module based on color layer mask supervision and a key region selection module based on a transformer due to its global modeling capability. Additionally, an unsupervised and unpaired cytoplasm generator network is firstly proposed to expand the long-tailed distribution dataset. Finally, experiments are performed on BC multicenter datasets. The proposed BC fine detection method outperforms other benchmarks in almost all the evaluation criteria, providing clarification and support for tasks such as cancer screenings.

Siyi Chen, Kai Wang, Weicong Pang et al.

Open-set land-cover analysis in remote sensing requires the ability to achieve fine-grained spatial localization and semantically open categorization. This involves not only detecting and segmenting novel objects without categorical supervision but also assigning them interpretable semantic labels through multimodal reasoning. In this study, we introduce OSDA, an integrated three-stage framework for annotation-free open-set land-cover discovery, segmentation, and description. The pipeline consists of: (1) precise discovery and mask extraction with a promptable fine-tuned segmentation model (SAM), (2) semantic attribution and contextual description via a two-phase fine-tuned multimodal large language model (MLLM), and (3) LLM-as-judge and manual scoring of the MLLMs evaluation. By combining pixel-level accuracy with high-level semantic understanding, OSDA addresses key challenges in open-world remote sensing interpretation. Designed to be architecture-agnostic and label-free, the framework supports robust evaluation across diverse satellite imagery without requiring manual annotation. Our work provides a scalable and interpretable solution for dynamic land-cover monitoring, showing strong potential for automated cartographic updating and large-scale earth observation analysis.

Xuanru Zhou, Jiarun Liu, Shoujun Yu et al.

In medical imaging, 4D MRI enables dynamic 3D visualization, yet the trade-off between spatial and temporal resolution requires prolonged scan time that can compromise temporal fidelity--especially during rapid, large-amplitude motion. Traditional approaches typically rely on registration-based interpolation to generate intermediate frames. However, these methods struggle with large deformations, resulting in misregistration, artifacts, and diminished spatial consistency. To address these challenges, we propose TSSC-Net, a novel framework that generates intermediate frames while preserving spatial consistency. To improve temporal fidelity under fast motion, our diffusion-based temporal super-resolution network generates intermediate frames using the start and end frames as key references, achieving 6x temporal super-resolution in a single inference step. Additionally, we introduce a novel tri-directional Mamba-based module that leverages long-range contextual information to effectively resolve spatial inconsistencies arising from cross-slice misalignment, thereby enhancing volumetric coherence and correcting cross-slice errors. Extensive experiments were performed on the public ACDC cardiac MRI dataset and a real-world dynamic 4D knee joint dataset. The results demonstrate that TSSC-Net can generate high-resolution dynamic MRI from fast-motion data while preserving structural fidelity and spatial consistency.

Weijian Huang, Cheng Li, Hao Yang et al.

Recently, vision-language representation learning has made remarkable advancements in building up medical foundation models, holding immense potential for transforming the landscape of clinical research and medical care. The underlying hypothesis is that the rich knowledge embedded in radiology reports can effectively assist and guide the learning process, reducing the need for additional labels. However, these reports tend to be complex and sometimes even consist of redundant descriptions that make the representation learning too challenging to capture the key semantic information. This paper develops a novel iterative vision-language representation learning framework by proposing a key semantic knowledge-emphasized report refinement method. Particularly, raw radiology reports are refined to highlight the key information according to a constructed clinical dictionary and two model-optimized knowledge-enhancement metrics. The iterative framework is designed to progressively learn, starting from gaining a general understanding of the patient's condition based on raw reports and gradually refines and extracts critical information essential to the fine-grained analysis tasks. The effectiveness of the proposed framework is validated on various downstream medical image analysis tasks, including disease classification, region-of-interest segmentation, and phrase grounding. Our framework surpasses seven state-of-the-art methods in both fine-tuning and zero-shot settings, demonstrating its encouraging potential for different clinical applications.

Junjun He, Jin Ye, Cheng Li et al.

Recent studies have witnessed the effectiveness of 3D convolutions on segmenting volumetric medical images. Compared with the 2D counterparts, 3D convolutions can capture the spatial context in three dimensions. Nevertheless, models employing 3D convolutions introduce more trainable parameters and are more computationally complex, which may lead easily to model overfitting especially for medical applications with limited available training data. This paper aims to improve the effectiveness and efficiency of 3D convolutions by introducing a novel Group Shift Pointwise Convolution (GSP-Conv). GSP-Conv simplifies 3D convolutions into pointwise ones with 1x1x1 kernels, which dramatically reduces the number of model parameters and FLOPs (e.g. 27x fewer than 3D convolutions with 3x3x3 kernels). Naïve pointwise convolutions with limited receptive fields cannot make full use of the spatial image context. To address this problem, we propose a parameter-free operation, Group Shift (GS), which shifts the feature maps along with different spatial directions in an elegant way. With GS, pointwise convolutions can access features from different spatial locations, and the limited receptive fields of pointwise convolutions can be compensated. We evaluate the proposed methods on two datasets, PROMISE12 and BraTS18. Results show that our method, with substantially decreased model complexity, achieves comparable or even better performance than models employing 3D convolutions.

Cheng Li, Sunil Gupta, Santu Rana et al.

Scientific experiments are usually expensive due to complex experimental preparation and processing. Experimental design is therefore involved with the task of finding the optimal experimental input that results in the desirable output by using as few experiments as possible. Experimenters can often acquire the knowledge about the location of the global optimum. However, they do not know how to exploit this knowledge to accelerate experimental design. In this paper, we adopt the technique of Bayesian optimization for experimental design since Bayesian optimization has established itself as an efficient tool for optimizing expensive black-box functions. Again, it is unknown how to incorporate the expert prior knowledge about the global optimum into Bayesian optimization process. To address it, we represent the expert knowledge about the global optimum via placing a prior distribution on it and we then derive its posterior distribution. An efficient Bayesian optimization approach has been proposed via posterior sampling on the posterior distribution of the global optimum. We theoretically analyze the convergence of the proposed algorithm and discuss the robustness of incorporating expert prior. We evaluate the efficiency of our algorithm by optimizing synthetic functions and tuning hyperparameters of classifiers along with a real-world experiment on the synthesis of short polymer fiber. The results clearly demonstrate the advantages of our proposed method.

Shuo Huang, Ke wu, Xiaolin Meng et al.

The non-rigid registration between CT data and ultrasonic images of liver can facilitate the diagnosis and treatment, which has been widely studied in recent years. To improve the registration accuracy of the Demons model on the non-rigid registration between 3D CT liver data and 2D ultrasonic images, a novel boundary extraction and enhancement method based on radial directional local intuitionistic fuzzy entropy in the polar coordinates has been put forward, and a new registration workflow has been provided. Experiments show that our method can acquire high-accuracy registration results. Experiments also show that the accuracy of the results of our method is higher than that of the original Demons method and the Demons method using simulated ultrasonic image by Field II. The operation time of our registration workflow is about 30 seconds, and it can be used in the surgery.

Jinting Chen, Zhaocheng Zhu, Cheng Li et al.

Deep convolutional neural networks have been proved successful on a wide range of tasks, yet they are still hindered by their large computation cost in many industrial scenarios. In this paper, we propose to reduce such cost for CNNs through a self-adaptive network pruning method (SANP). Our method introduces a general Saliency-and-Pruning Module (SPM) for each convolutional layer, which learns to predict saliency scores and applies pruning for each channel. Given a total computation budget, SANP adaptively determines the pruning strategy with respect to each layer and each sample, such that the average computation cost meets the budget. This design allows SANP to be more efficient in computation, as well as more robust to datasets and backbones. Extensive experiments on 2 datasets and 3 backbones show that SANP surpasses state-of-the-art methods in both classification accuracy and pruning rate.

Wei Zhang, Wei Wei, Lingjie Xu et al.

Alibaba has China's largest e-commerce platform. To support its diverse businesses, Alibaba has its own large-scale data centers providing the computing foundation for a wide variety of software applications. Among these applications, deep learning (DL) has been playing an important role in delivering services like image recognition, objection detection, text recognition, recommendation, and language processing. To build more efficient data centers that deliver higher performance for these DL applications, it is important to understand their computational needs and use that information to guide the design of future computing infrastructure. An effective way to achieve this is through benchmarks that can fully represent Alibaba's DL applications.

Fei Wang, Mengqing Jiang, Chen Qian et al.

In this work, we propose "Residual Attention Network", a convolutional neural network using attention mechanism which can incorporate with state-of-art feed forward network architecture in an end-to-end training fashion. Our Residual Attention Network is built by stacking Attention Modules which generate attention-aware features. The attention-aware features from different modules change adaptively as layers going deeper. Inside each Attention Module, bottom-up top-down feedforward structure is used to unfold the feedforward and feedback attention process into a single feedforward process. Importantly, we propose attention residual learning to train very deep Residual Attention Networks which can be easily scaled up to hundreds of layers. Extensive analyses are conducted on CIFAR-10 and CIFAR-100 datasets to verify the effectiveness of every module mentioned above. Our Residual Attention Network achieves state-of-the-art object recognition performance on three benchmark datasets including CIFAR-10 (3.90% error), CIFAR-100 (20.45% error) and ImageNet (4.8% single model and single crop, top-5 error). Note that, our method achieves 0.6% top-1 accuracy improvement with 46% trunk depth and 69% forward FLOPs comparing to ResNet-200. The experiment also demonstrates that our network is robust against noisy labels.

Shizhan Zhu, Cheng Li, Chen Change Loy et al.

Dataset bias is a well known problem in object recognition domain. This issue, nonetheless, is rarely explored in face alignment research. In this study, we show that dataset plays an integral part of face alignment performance. Specifically, owing to face alignment dataset bias, training on one database and testing on another or unseen domain would lead to poor performance. Creating an unbiased dataset through combining various existing databases, however, is non-trivial as one has to exhaustively re-label the landmarks for standardisation. In this work, we propose a simple and yet effective method to bridge the disparate annotation spaces between databases, making datasets fusion possible. We show extensive results on combining various popular databases (LFW, AFLW, LFPW, HELEN) for improved cross-dataset and unseen data alignment.