Jiang Zhang

Jiabao Sheng, Yuanpeng Zhang, Jing Cai et al.

The prediction of adaptive radiation therapy (ART) prior to radiation therapy (RT) for nasopharyngeal carcinoma (NPC) patients is important to reduce toxicity and prolong the survival of patients. Currently, due to the complex tumor micro-environment, a single type of high-resolution image can provide only limited information. Meanwhile, the traditional softmax-based loss is insufficient for quantifying the discriminative power of a model. To overcome these challenges, we propose a supervised multi-view contrastive learning method with an additive margin (MMCon). For each patient, four medical images are considered to form multi-view positive pairs, which can provide additional information and enhance the representation of medical images. In addition, the embedding space is learned by means of contrastive learning. NPC samples from the same patient or with similar labels will remain close in the embedding space, while NPC samples with different labels will be far apart. To improve the discriminative ability of the loss function, we incorporate a margin into the contrastive learning. Experimental result show this new learning objective can be used to find an embedding space that exhibits superior discrimination ability for NPC images.

Zhang Zhang, Ruyi Tao, Yongzai Tao et al.

Network completion is a harder problem than link prediction because it does not only try to infer missing links but also nodes. Different methods have been proposed to solve this problem, but few of them employed structural information - the similarity of local connection patterns. In this paper, we propose a model named C-GIN to capture the local structural patterns from the observed part of a network based on the Graph Auto-Encoder framework equipped with Graph Isomorphism Network model and generalize these patterns to complete the whole graph. Experiments and analysis on synthetic and real-world networks from different domains show that competitive performance can be achieved by C-GIN with less information being needed, and higher accuracy compared with baseline prediction models in most cases can be obtained. We further proposed a metric "Reachable Clustering Coefficient(CC)" based on network structure. And experiments show that our model perform better on a network with higher Reachable CC.

Jiabao Sheng, SaiKit Lam, Jiang Zhang et al.

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence of unpredictability arising from disparities in data sources and medical imaging equipment. In order to overcome this challenge and facilitate the integration of their joint application to specific medical objectives, this study aims to develop a fusion methodology that mitigates the disparities inherent in omics data. The utilization of the multi-kernel late-fusion method has gained significant popularity as an effective strategy for addressing this particular challenge. An efficient representation of the data may be achieved by utilizing a suitable single-kernel function to map the inherent features and afterward merging them in a space with a high number of dimensions. This approach effectively addresses the differences noted before. The inflexibility of label fitting poses a constraint on the use of multi-kernel late-fusion methods in complex nasopharyngeal carcinoma (NPC) datasets, hence affecting the efficacy of general classifiers in dealing with high-dimensional characteristics. This innovative methodology aims to increase the disparity between the two cohorts, hence providing a more flexible structure for the allocation of labels. The examination of the NPC-ContraParotid dataset demonstrates the model's robustness and efficacy, indicating its potential as a valuable tool for predicting distant metastases in patients with nasopharyngeal carcinoma (NPC).

Jiang Zhang, Konstantinos Psounis, Muhammad Haroon et al.

Online behavioral advertising, and the associated tracking paraphernalia, poses a real privacy threat. Unfortunately, existing privacy-enhancing tools are not always effective against online advertising and tracking. We propose Harpo, a principled learning-based approach to subvert online behavioral advertising through obfuscation. Harpo uses reinforcement learning to adaptively interleave real page visits with fake pages to distort a tracker's view of a user's browsing profile. We evaluate Harpo against real-world user profiling and ad targeting models used for online behavioral advertising. The results show that Harpo improves privacy by triggering more than 40% incorrect interest segments and 6x higher bid values. Harpo outperforms existing obfuscation tools by as much as 16x for the same overhead. Harpo is also able to achieve better stealthiness to adversarial detection than existing obfuscation tools. Harpo meaningfully advances the state-of-the-art in leveraging obfuscation to subvert online behavioral advertising

Yaoxin Li, Jing Liu, Guozheng Lin et al.

In computer science, there exist a large number of optimization problems defined on graphs, that is to find a best node state configuration or a network structure such that the designed objective function is optimized under some constraints. However, these problems are notorious for their hardness to solve because most of them are NP-hard or NP-complete. Although traditional general methods such as simulated annealing (SA), genetic algorithms (GA) and so forth have been devised to these hard problems, their accuracy and time consumption are not satisfying in practice. In this work, we proposed a simple, fast, and general algorithm framework based on advanced automatic differentiation technique empowered by deep learning frameworks. By introducing Gumbel-softmax technique, we can optimize the objective function directly by gradient descent algorithm regardless of the discrete nature of variables. We also introduce evolution strategy to parallel version of our algorithm. We test our algorithm on three representative optimization problems on graph including modularity optimization from network science, Sherrington-Kirkpatrick (SK) model from statistical physics, maximum independent set (MIS) and minimum vertex cover (MVC) problem from combinatorial optimization on graph. High-quality solutions can be obtained with much less time consuming compared to traditional approaches.

Mengyuan Chen, Jiang Zhang, Zhang Zhang et al.

Network structures in various backgrounds play important roles in social, technological, and biological systems. However, the observable network structures in real cases are often incomplete or unavailable due to measurement errors or private protection issues. Therefore, inferring the complete network structure is useful for understanding complex systems. The existing studies have not fully solved the problem of inferring network structure with partial or no information about connections or nodes. In this paper, we tackle the problem by utilizing time series data generated by network dynamics. We regard the network inference problem based on dynamical time series data as a problem of minimizing errors for predicting future states and proposed a novel data-driven deep learning model called Gumbel Graph Network (GGN) to solve the two kinds of network inference problems: Network Reconstruction and Network Completion. For the network reconstruction problem, the GGN framework includes two modules: the dynamics learner and the network generator. For the network completion problem, GGN adds a new module called the States Learner to infer missing parts of the network. We carried out experiments on discrete and continuous time series data. The experiments show that our method can reconstruct up to 100% network structure on the network reconstruction task. While the model can also infer the unknown parts of the structure with up to 90% accuracy when some nodes are missing. And the accuracy decays with the increase of the fractions of missing nodes. Our framework may have wide application areas where the network structure is hard to obtained and the time series data is rich.