Wei Liu

Kaiyuan Yang, Fabio Musio, Yihui Ma et al.

The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to affect the risk, severity, and clinical outcome of serious neurovascular diseases. However, characterizing the highly variable CoW anatomy is still a manual and time-consuming expert task. The CoW is usually imaged by two non-invasive angiographic imaging modalities, magnetic resonance angiography (MRA) and computed tomography angiography (CTA), but there exist limited datasets with annotations on CoW anatomy, especially for CTA. Therefore, we organized the TopCoW challenge with the release of an annotated CoW dataset. The TopCoW dataset is the first public dataset with voxel-level annotations for 13 CoW vessel components, enabled by virtual reality technology. It is also the first large dataset using 200 pairs of MRA and CTA from the same patients. As part of the benchmark, we invited submissions worldwide and attracted over 250 registered participants from six continents. The submissions were evaluated on both internal and external test datasets of 226 scans from over five centers. The top performing teams achieved over 90% Dice scores at segmenting the CoW components, over 80% F1 scores at detecting key CoW components, and over 70% balanced accuracy at classifying CoW variants for nearly all test sets. The best algorithms also showed clinical potential in classifying fetal-type posterior cerebral artery and locating aneurysms with CoW anatomy. TopCoW demonstrated the utility and versatility of CoW segmentation algorithms for a wide range of downstream clinical applications with explainability. The annotated datasets and best performing algorithms have been released as public Zenodo records to foster further methodological development and clinical tool building.

Yang Qiu, Yixiong Zou, Jun Wang et al.

Out-of-distribution generalization under distributional shifts remains a critical challenge for graph neural networks. Existing methods generally adopt the Invariant Risk Minimization (IRM) framework, requiring costly environment annotations or heuristically generated synthetic splits. To circumvent these limitations, in this work, we aim to develop an IRM-free method for capturing causal subgraphs. We first identify that causal subgraphs exhibit substantially smaller distributional variations than non-causal components across diverse environments, which we formalize as the Invariant Distribution Criterion and theoretically prove in this paper. Building on this criterion, we systematically uncover the quantitative relationship between distributional shift and representation norm for identifying the causal subgraph, and investigate its underlying mechanisms in depth. Finally, we propose an IRM-free method by introducing a norm-guided invariant distribution objective for causal subgraph discovery and prediction. Extensive experiments on two widely used benchmarks demonstrate that our method consistently outperforms state-of-the-art methods in graph generalization.

Linqiang Guo, Wei Liu, Yi Wen Heng et al.

Mobile Graphical User Interface (GUI) agents aim to autonomously complete tasks within or across apps based on user instructions. While recent Multimodal Large Language Models (MLLMs) enable these agents to interpret UI screens and perform actions, existing agents remain fundamentally reactive. They reason over the current UI screen but lack a structured representation of the app navigation flow, limiting GUI agents' ability to understand execution context, detect unexpected execution results, and recover from errors. We introduce Agent-SAMA, a state-aware multi-agent framework that models app execution as a Finite State Machine (FSM), treating UI screens as states and user actions as transitions. Agent-SAMA implements four specialized agents that collaboratively construct and use FSMs in real time to guide task planning, execution verification, and recovery. We evaluate Agent-SAMA on two types of benchmarks: cross-app (Mobile-Eval-E, SPA-Bench) and mostly single-app (AndroidWorld). On Mobile-Eval-E, Agent-SAMA achieves an 84.0% success rate and a 71.9% recovery rate. On SPA-Bench, it reaches an 80.0% success rate with a 66.7% recovery rate. Compared to prior methods, Agent-SAMA improves task success by up to 12% and recovery success by 13.8%. On AndroidWorld, Agent-SAMA achieves a 63.7% success rate, outperforming the baselines. Our results demonstrate that structured state modeling enhances robustness and can serve as a lightweight, model-agnostic memory layer for future GUI agents.

Wei Liu, Xiaogang Chen, Chunhua Shen et al.

The process of using one image to guide the filtering process of another one is called Guided Image Filtering (GIF). The main challenge of GIF is the structure inconsistency between the guidance image and the target image. Besides, noise in the target image is also a challenging issue especially when it is heavy. In this paper, we propose a general framework for Robust Guided Image Filtering (RGIF), which contains a data term and a smoothness term, to solve the two issues mentioned above. The data term makes our model simultaneously denoise the target image and perform GIF which is robust against the heavy noise. The smoothness term is able to make use of the property of both the guidance image and the target image which is robust against the structure inconsistency. While the resulting model is highly non-convex, it can be solved through the proposed Iteratively Re-weighted Least Squares (IRLS) in an efficient manner. For challenging applications such as guided depth map upsampling, we further develop a data-driven parameter optimization scheme to properly determine the parameter in our model. This optimization scheme can help to preserve small structures and sharp depth edges even for a large upsampling factor (8x for example). Moreover, the specially designed structure of the data term and the smoothness term makes our model perform well in edge-preserving smoothing for single-image tasks (i.e., the guidance image is the target image itself). This paper is an extension of our previous work [1], [2].