Jianhua Zhang

Chen Shen, Chunfeng Lian, Wanqing Zhang et al.

Forensic pathology is critical in determining the cause and manner of death through post-mortem examinations, both macroscopic and microscopic. The field, however, grapples with issues such as outcome variability, laborious processes, and a scarcity of trained professionals. This paper presents SongCi, an innovative visual-language model (VLM) designed specifically for forensic pathology. SongCi utilizes advanced prototypical cross-modal self-supervised contrastive learning to enhance the accuracy, efficiency, and generalizability of forensic analyses. It was pre-trained and evaluated on a comprehensive multi-center dataset, which includes over 16 million high-resolution image patches, 2,228 vision-language pairs of post-mortem whole slide images (WSIs), and corresponding gross key findings, along with 471 distinct diagnostic outcomes. Our findings indicate that SongCi surpasses existing multi-modal AI models in many forensic pathology tasks, performs comparably to experienced forensic pathologists and significantly better than less experienced ones, and provides detailed multi-modal explainability, offering critical assistance in forensic investigations. To the best of our knowledge, SongCi is the first VLM specifically developed for forensic pathological analysis and the first large-vocabulary computational pathology (CPath) model that directly processes gigapixel WSIs in forensic science.

Jingjing Liu, Yinchao Han, Xianchao Xiu et al.

Infrared small target detection (ISTD) is one of the key techniques in image processing. Although deep unfolding networks (DUNs) have demonstrated promising performance in ISTD due to their model interpretability and data adaptability, existing methods still face significant challenges in parameter lightweightness and noise robustness. In this regard, we propose a highly lightweight framework based on robust principal component analysis (RPCA) called L-RPCANet. Technically, a hierarchical bottleneck structure is constructed to reduce and increase the channel dimension in the single-channel input infrared image to achieve channel-wise feature refinement, with bottleneck layers designed in each module to extract features. This reduces the number of channels in feature extraction and improves the lightweightness of network parameters. Furthermore, a noise reduction module is embedded to enhance the robustness against complex noise. In addition, squeeze-and-excitation networks (SENets) are leveraged as a channel attention mechanism to focus on the varying importance of different features across channels, thereby achieving excellent performance while maintaining both lightweightness and robustness. Extensive experiments on the ISTD datasets validate the superiority of our proposed method compared with state-of-the-art methods covering RPCANet, DRPCANet, and RPCANet++. The code will be available at https://github.com/xianchaoxiu/L-RPCANet.

Jingjing Liu, Nian Wu, Xianchao Xiu et al.

Non-negative matrix factorization (NMF) is a popular unsupervised learning approach widely used in image clustering. However, in real-world clustering scenarios, most existing NMF methods are highly sensitive to noise corruption and are unable to effectively leverage limited supervised information. To overcome these drawbacks, we propose a unified non-convex framework with label propagation called robust orthogonal nonnegative matrix factorization (RONMF). This method not only considers the graph Laplacian and label propagation as regularization terms but also introduces a more effective non-convex structure to measure the reconstruction error and imposes orthogonal constraints on the basis matrix to reduce the noise corruption, thereby achieving higher robustness. To solve RONMF, we develop an alternating direction method of multipliers (ADMM)-based optimization algorithm. In particular, all subproblems have closed-form solutions, which ensures its efficiency. Experimental evaluations on eight public image datasets demonstrate that the proposed RONMF outperforms state-of-the-art NMF methods across various standard metrics and shows excellent robustness. The code will be available at https://github.com/slinda-liu.