Yan Xu

Zhiyun Song, Penghui Du, Junpeng Yan et al.

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate on the extraction of nucleus-level information, which is essential for pathologic analysis. In this work, we propose a novel nucleus-aware self-supervised pretraining framework for histopathology images. The framework aims to capture the nuclear morphology and distribution information through unpaired image-to-image translation between histopathology images and pseudo mask images. The generation process is modulated by both conditional and stochastic style representations, ensuring the reality and diversity of the generated histopathology images for pretraining. Further, an instance segmentation guided strategy is employed to capture instance-level information. The experiments on 7 datasets show that the proposed pretraining method outperforms supervised ones on Kather classification, multiple instance learning, and 5 dense-prediction tasks with the transfer learning protocol, and yields superior results than other self-supervised approaches on 8 semi-supervised tasks. Our project is publicly available at https://github.com/zhiyuns/UNITPathSSL.

Shu Liu, Enquan Huang, Ziyu Zhou et al.

Facial attractiveness prediction (FAP) aims to assess facial attractiveness automatically based on human aesthetic perception. Previous methods using deep convolutional neural networks have improved the performance, but their large-scale models have led to a deficiency in flexibility. In addition, most methods fail to take full advantage of the dataset. In this paper, we present a novel end-to-end FAP approach that integrates dual label distribution and lightweight design. The manual ratings, attractiveness score, and standard deviation are aggregated explicitly to construct a dual-label distribution to make the best use of the dataset, including the attractiveness distribution and the rating distribution. Such distributions, as well as the attractiveness score, are optimized under a joint learning framework based on the label distribution learning (LDL) paradigm. The data processing is simplified to a minimum for a lightweight design, and MobileNetV2 is selected as our backbone. Extensive experiments are conducted on two benchmark datasets, where our approach achieves promising results and succeeds in balancing performance and efficiency. Ablation studies demonstrate that our delicately designed learning modules are indispensable and correlated. Additionally, the visualization indicates that our approach can perceive facial attractiveness and capture attractive facial regions to facilitate semantic predictions. The code is available at https://github.com/enquan/2D_FAP.

Ziniu Qian, Kailu Li, Maode Lai et al.

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is time-consuming and labor-intensive. As a subset of weakly supervised learning, Multiple Instance Learning (MIL) has been proven to be effective in segmentation. However, there is a lack of related information between instances in MIL, which limits the further improvement of segmentation performance. In this paper, we propose a novel weakly supervised method for pixel-level segmentation in histopathology images, which introduces Transformer into the MIL framework to capture global or long-range dependencies. The multi-head self-attention in the Transformer establishes the relationship between instances, which solves the shortcoming that instances are independent of each other in MIL. In addition, deep supervision is introduced to overcome the limitation of annotations in weakly supervised methods and make the better utilization of hierarchical information. The state-of-the-art results on the colon cancer dataset demonstrate the superiority of the proposed method compared with other weakly supervised methods. It is worth believing that there is a potential of our approach for various applications in medical images.

Zhiwen Yang, Yang Zhou, Hui Zhang et al.

Multi-center positron emission tomography (PET) image synthesis aims at recovering low-dose PET images from multiple different centers. The generalizability of existing methods can still be suboptimal for a multi-center study due to domain shifts, which result from non-identical data distribution among centers with different imaging systems/protocols. While some approaches address domain shifts by training specialized models for each center, they are parameter inefficient and do not well exploit the shared knowledge across centers. To address this, we develop a generalist model that shares architecture and parameters across centers to utilize the shared knowledge. However, the generalist model can suffer from the center interference issue, \textit{i.e.} the gradient directions of different centers can be inconsistent or even opposite owing to the non-identical data distribution. To mitigate such interference, we introduce a novel dynamic routing strategy with cross-layer connections that routes data from different centers to different experts. Experiments show that our generalist model with dynamic routing (DRMC) exhibits excellent generalizability across centers. Code and data are available at: https://github.com/Yaziwel/Multi-Center-PET-Image-Synthesis.

Chu Han, Xipeng Pan, Lixu Yan et al.

Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma (LUAD) is the most common subtype. Exploiting the potential value of the histopathology images can promote precision medicine in oncology. Tissue segmentation is the basic upstream task of histopathology image analysis. Existing deep learning models have achieved superior segmentation performance but require sufficient pixel-level annotations, which is time-consuming and expensive. To enrich the label resources of LUAD and to alleviate the annotation efforts, we organize this challenge WSSS4LUAD to call for the outstanding weakly-supervised semantic segmentation (WSSS) techniques for histopathology images of LUAD. Participants have to design the algorithm to segment tumor epithelial, tumor-associated stroma and normal tissue with only patch-level labels. This challenge includes 10,091 patch-level annotations (the training set) and over 130 million labeled pixels (the validation and test sets), from 87 WSIs (67 from GDPH, 20 from TCGA). All the labels were generated by a pathologist-in-the-loop pipeline with the help of AI models and checked by the label review board. Among 532 registrations, 28 teams submitted the results in the test phase with over 1,000 submissions. Finally, the first place team achieved mIoU of 0.8413 (tumor: 0.8389, stroma: 0.7931, normal: 0.8919). According to the technical reports of the top-tier teams, CAM is still the most popular approach in WSSS. Cutmix data augmentation has been widely adopted to generate more reliable samples. With the success of this challenge, we believe that WSSS approaches with patch-level annotations can be a complement to the traditional pixel annotations while reducing the annotation efforts. The entire dataset has been released to encourage more researches on computational pathology in LUAD and more novel WSSS techniques.

Chengxiao Sun, Yan Xu, Jialun Pei et al.

In recent years, saliency ranking has emerged as a challenging task focusing on assessing the degree of saliency at instance-level. Being subjective, even humans struggle to identify the precise order of all salient instances. Previous approaches undertake the saliency ranking by directly sorting the rank scores of salient instances, which have not explicitly resolved the inherent ambiguities. To overcome this limitation, we propose the ranking by partition paradigm, which segments unordered salient instances into partitions and then ranks them based on the correlations among these partitions. The ranking by partition paradigm alleviates ranking ambiguities in a general sense, as it consistently improves the performance of other saliency ranking models. Additionally, we introduce the Dense Pyramid Transformer (DPT) to enable global cross-scale interactions, which significantly enhances feature interactions with reduced computational burden. Extensive experiments demonstrate that our approach outperforms all existing methods. The code for our method is available at \url{https://github.com/ssecv/PSR}.

Yang Zhou, Yongjian Wu, Zihua Wang et al.

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and laborious for the high nuclei density. To alleviate the annotation burden, we seek to solve the problem through image-level weakly supervised learning, which is underexplored for nuclei instance segmentation. Compared with most existing methods using other weak annotations (scribble, point, etc.) for nuclei instance segmentation, our method is more labor-saving. The obstacle to using image-level annotations in nuclei instance segmentation is the lack of adequate location information, leading to severe nuclei omission or overlaps. In this paper, we propose a novel image-level weakly supervised method, called cyclic learning, to solve this problem. Cyclic learning comprises a front-end classification task and a back-end semi-supervised instance segmentation task to benefit from multi-task learning (MTL). We utilize a deep learning classifier with interpretability as the front-end to convert image-level labels to sets of high-confidence pseudo masks and establish a semi-supervised architecture as the back-end to conduct nuclei instance segmentation under the supervision of these pseudo masks. Most importantly, cyclic learning is designed to circularly share knowledge between the front-end classifier and the back-end semi-supervised part, which allows the whole system to fully extract the underlying information from image-level labels and converge to a better optimum. Experiments on three datasets demonstrate the good generality of our method, which outperforms other image-level weakly supervised methods for nuclei instance segmentation, and achieves comparable performance to fully-supervised methods.

Yinghong Liao, Wending Zhou, Xu Yan et al.

Measuring and alleviating the discrepancies between the synthetic (source) and real scene (target) data is the core issue for domain adaptive semantic segmentation. Though recent works have introduced depth information in the source domain to reinforce the geometric and semantic knowledge transfer, they cannot extract the intrinsic 3D information of objects, including positions and shapes, merely based on 2D estimated depth. In this work, we propose a novel Geometry-Aware Network for Domain Adaptation (GANDA), leveraging more compact 3D geometric point cloud representations to shrink the domain gaps. In particular, we first utilize the auxiliary depth supervision from the source domain to obtain the depth prediction in the target domain to accomplish structure-texture disentanglement. Beyond depth estimation, we explicitly exploit 3D topology on the point clouds generated from RGB-D images for further coordinate-color disentanglement and pseudo-labels refinement in the target domain. Moreover, to improve the 2D classifier in the target domain, we perform domain-invariant geometric adaptation from source to target and unify the 2D semantic and 3D geometric segmentation results in two domains. Note that our GANDA is plug-and-play in any existing UDA framework. Qualitative and quantitative results demonstrate that our model outperforms state-of-the-arts on GTA5->Cityscapes and SYNTHIA->Cityscapes.

Ziqing Ji, Pranav Kulkarni, Marko Neskovic et al.

With news and information being as easy to access as they currently are, it is more important than ever to ensure that people are not mislead by what they read. Recently, the rise of neural fake news (AI-generated fake news) and its demonstrated effectiveness at fooling humans has prompted the development of models to detect it. One such model is the Grover model, which can both detect neural fake news to prevent it, and generate it to demonstrate how a model could be misused to fool human readers. In this work we explore the Grover model's fake news detection capabilities by performing targeted attacks through perturbations on input news articles. Through this we test Grover's resilience to these adversarial attacks and expose some potential vulnerabilities which should be addressed in further iterations to ensure it can detect all types of fake news accurately.

Futian Weng, Yuanting Ma, Jinghan Sun et al.

Dermatological diseases are among the most common disorders worldwide. This paper presents the first study of the interpretability and imbalanced semi-supervised learning of the multiclass intelligent skin diagnosis framework (ISDL) using 58,457 skin images with 10,857 unlabeled samples. Pseudo-labelled samples from minority classes have a higher probability at each iteration of class-rebalancing self-training, thereby promoting the utilization of unlabeled samples to solve the class imbalance problem. Our ISDL achieved a promising performance with an accuracy of 0.979, sensitivity of 0.975, specificity of 0.973, macro-F1 score of 0.974 and area under the receiver operating characteristic curve (AUC) of 0.999 for multi-label skin disease classification. The Shapley Additive explanation (SHAP) method is combined with our ISDL to explain how the deep learning model makes predictions. This finding is consistent with the clinical diagnosis. We also proposed a sampling distribution optimisation strategy to select pseudo-labelled samples in a more effective manner using ISDLplus. Furthermore, it has the potential to relieve the pressure placed on professional doctors, as well as help with practical issues associated with a shortage of such doctors in rural areas.

Qi Lv, Ziqiang Cao, Lei Geng et al.

The lack of label data is one of the significant bottlenecks for Chinese Spelling Check (CSC). Existing researches use the method of automatic generation by exploiting unlabeled data to expand the supervised corpus. However, there is a big gap between the real input scenario and automatic generated corpus. Thus, we develop a competitive general speller ECSpell which adopts the Error Consistent masking strategy to create data for pretraining. This error consistency masking strategy is used to specify the error types of automatically generated sentences which is consistent with real scene. The experimental result indicates our model outperforms previous state-of-the-art models on the general benchmark. Moreover, spellers often work within a particular domain in real life. Due to lots of uncommon domain terms, experiments on our built domain specific datasets show that general models perform terribly. Inspired by the common practice of input methods, we propose to add an alterable user dictionary to handle the zero-shot domain adaption problem. Specifically, we attach a User Dictionary guided inference module (UD) to a general token classification based speller. Our experiments demonstrate that ECSpell$^{UD}$, namely ECSpell combined with UD, surpasses all the other baselines largely, even approaching the performance on the general benchmark.

Yang Zhou, Yongjian Wu, Jiya Saiyin et al.

Prompt tuning methods have achieved remarkable success in parameter-efficient fine-tuning on large pre-trained models. However, their application to dual-modal fusion-based visual-language pre-trained models (VLPMs), such as GLIP, has encountered issues. Existing prompt tuning methods have not effectively addressed the modal mapping and aligning problem for tokens in different modalities, leading to poor transfer generalization. To address this issue, we propose Synchronous Dual Prompt Tuning (SDPT). SDPT initializes a single set of learnable unified prototype tokens in the established modal aligning space to represent the aligned semantics of text and image modalities for downstream tasks. Furthermore, SDPT establishes inverse linear projections that require no training to embed the information of unified prototype tokens into the input space of different modalities. The inverse linear projections allow the unified prototype token to synchronously represent the two modalities and enable SDPT to share the unified semantics of text and image for downstream tasks across different modal prompts. Experimental results demonstrate that SDPT assists fusion-based VLPMs to achieve superior outcomes with only 0.04\% of model parameters for training across various scenarios, outperforming other single- or dual-modal methods. The code will be released at https://github.com/wuyongjianCODE/SDPT.

Hao Du, Qihua Dong, Yan Xu et al.

Medical image segmentation is almost the most important pre-processing procedure in computer-aided diagnosis but is also a very challenging task due to the complex shapes of segments and various artifacts caused by medical imaging, (i.e., low-contrast tissues, and non-homogenous textures). In this paper, we propose a simple yet effective segmentation framework that incorporates the geometric prior and contrastive similarity into the weakly-supervised segmentation framework in a loss-based fashion. The proposed geometric prior built on point cloud provides meticulous geometry to the weakly-supervised segmentation proposal, which serves as better supervision than the inherent property of the bounding-box annotation (i.e., height and width). Furthermore, we propose contrastive similarity to encourage organ pixels to gather around in the contrastive embedding space, which helps better distinguish low-contrast tissues. The proposed contrastive embedding space can make up for the poor representation of the conventionally-used gray space. Extensive experiments are conducted to verify the effectiveness and the robustness of the proposed weakly-supervised segmentation framework. The proposed framework is superior to state-of-the-art weakly-supervised methods on the following publicly accessible datasets: LiTS 2017 Challenge, KiTS 2021 Challenge, and LPBA40. We also dissect our method and evaluate the performance of each component.

Chunhui Ai, Derui Wang, Xu Yan et al.

With so many articles of varying qualities being produced every moment, it is a very urgent task to screen outstanding articles and commit them to social media. To our best knowledge, there is a lack of datasets and mature research works in identifying high-quality articles. Consequently, we conduct some surveys and finalize 7 objective indicators to annotate the quality of 10k articles. During annotation, we find that many characteristics of high-quality articles (e.g., background) rely more on extensive external knowledge than inner semantic information of articles. In response, we link extracted article entities to Baidu Encyclopedia, then propose Knowledge Enhanced article Quality Identification (KE-QI) dataset. To make better use of external knowledge, we propose a compound model which fuses the text and external knowledge information via a gate unit to classify the quality of an article. Our experimental results on KE-QI show that with initialization of our pre-trained Node2Vec model, our model achieves about 78\% $F_1$, outperforming other baselines.

Yongjian Wu, Yang Zhou, Jiya Saiyin et al.

Large-scale visual-language pre-trained models (VLPMs) have demonstrated exceptional performance in downstream object detection through text prompts for natural scenes. However, their application to zero-shot nuclei detection on histopathology images remains relatively unexplored, mainly due to the significant gap between the characteristics of medical images and the web-originated text-image pairs used for pre-training. This paper aims to investigate the potential of the object-level VLPM, Grounded Language-Image Pre-training (GLIP), for zero-shot nuclei detection. Specifically, we propose an innovative auto-prompting pipeline, named AttriPrompter, comprising attribute generation, attribute augmentation, and relevance sorting, to avoid subjective manual prompt design. AttriPrompter utilizes VLPMs' text-to-image alignment to create semantically rich text prompts, which are then fed into GLIP for initial zero-shot nuclei detection. Additionally, we propose a self-trained knowledge distillation framework, where GLIP serves as the teacher with its initial predictions used as pseudo labels, to address the challenges posed by high nuclei density, including missed detections, false positives, and overlapping instances. Our method exhibits remarkable performance in label-free nuclei detection, outperforming all existing unsupervised methods and demonstrating excellent generality. Notably, this work highlights the astonishing potential of VLPMs pre-trained on natural image-text pairs for downstream tasks in the medical field as well. Code will be released at https://github.com/wuyongjianCODE/AttriPrompter.

Shengyu Zhao, Jonathan Cui, Yilun Sheng et al.

Numerous task-specific variants of conditional generative adversarial networks have been developed for image completion. Yet, a serious limitation remains that all existing algorithms tend to fail when handling large-scale missing regions. To overcome this challenge, we propose a generic new approach that bridges the gap between image-conditional and recent modulated unconditional generative architectures via co-modulation of both conditional and stochastic style representations. Also, due to the lack of good quantitative metrics for image completion, we propose the new Paired/Unpaired Inception Discriminative Score (P-IDS/U-IDS), which robustly measures the perceptual fidelity of inpainted images compared to real images via linear separability in a feature space. Experiments demonstrate superior performance in terms of both quality and diversity over state-of-the-art methods in free-form image completion and easy generalization to image-to-image translation. Code is available at https://github.com/zsyzzsoft/co-mod-gan.

Shengyu Zhao, Yue Dong, Eric I-Chao Chang et al.

We present recursive cascaded networks, a general architecture that enables learning deep cascades, for deformable image registration. The proposed architecture is simple in design and can be built on any base network. The moving image is warped successively by each cascade and finally aligned to the fixed image; this procedure is recursive in a way that every cascade learns to perform a progressive deformation for the current warped image. The entire system is end-to-end and jointly trained in an unsupervised manner. In addition, enabled by the recursive architecture, one cascade can be iteratively applied for multiple times during testing, which approaches a better fit between each of the image pairs. We evaluate our method on 3D medical images, where deformable registration is most commonly applied. We demonstrate that recursive cascaded networks achieve consistent, significant gains and outperform state-of-the-art methods. The performance reveals an increasing trend as long as more cascades are trained, while the limit is not observed. Code is available at https://github.com/microsoft/Recursive-Cascaded-Networks.

Jiasen Zheng, Huajun Zhang, Xu Yan et al.

This paper addresses the limitations of large-scale language models in safety alignment and robustness by proposing a fine-tuning method that combines contrastive distillation with noise-robust training. The method freezes the backbone model and transfers the knowledge boundaries of the teacher model to the student model through distillation, thereby improving semantic consistency and alignment accuracy. At the same time, noise perturbations and robust optimization constraints are introduced during training to ensure that the model maintains stable predictive outputs under noisy and uncertain inputs. The overall framework consists of distillation loss, robustness loss, and a regularization term, forming a unified optimization objective that balances alignment ability with resistance to interference. To systematically validate its effectiveness, the study designs experiments from multiple perspectives, including distillation weight sensitivity, stability analysis under computation budgets and mixed-precision environments, and the impact of data noise and distribution shifts on model performance. Results show that the method significantly outperforms existing baselines in knowledge transfer, robustness, and overall safety, achieving the best performance across several key metrics. This work not only enriches the theoretical system of parameter-efficient fine-tuning but also provides a new solution for building safer and more trustworthy alignment mechanisms.

Yan Xu, Kris Kitani

Cross-view person matching and 3D human pose estimation in multi-camera networks are particularly difficult when the cameras are extrinsically uncalibrated. Existing efforts generally require large amounts of 3D data for training neural networks or known camera poses for geometric constraints to solve the problem. However, camera poses and 3D data annotation are usually expensive and not always available. We present a method, PME, that solves the two tasks without requiring either information. Our idea is to address cross-view person matching as a clustering problem using each person as a cluster center, then obtain correspondences from person matches, and estimate 3D human poses through multi-view triangulation and bundle adjustment. We solve the clustering problem by introducing a "size constraint" using the number of cameras and a "source constraint" using the fact that two people from the same camera view should not match, to narrow the solution space to a small feasible region. The 2D human poses used in clustering are obtained through a pre-trained 2D pose detector, so our method does not require expensive 3D training data for each new scene. We extensively evaluate our method on three open datasets and two indoor and outdoor datasets collected using arbitrarily set cameras. Our method outperforms other methods by a large margin on cross-view person matching, reaches SOTA performance on 3D human pose estimation without using either camera poses or 3D training data, and shows good generalization ability across five datasets of various environment settings.

Lejla Skelic, Yan Xu, Matthew Cox et al.

The role of Large Language Models (LLMs) has not been extensively explored in analog circuit design, which could benefit from a reasoning-based approach that transcends traditional optimization techniques. In particular, despite their growing relevance, there are no benchmarks to assess LLMs' reasoning capability about circuits. Therefore, we created the CIRCUIT dataset consisting of 510 question-answer pairs spanning various levels of analog-circuit-related subjects. The best-performing model on our dataset, GPT-4o, achieves 48.04% accuracy when evaluated on the final numerical answer. To evaluate the robustness of LLMs on our dataset, we introduced a unique feature that enables unit-test-like evaluation by grouping questions into unit tests. In this case, GPT-4o can only pass 27.45% of the unit tests, highlighting that the most advanced LLMs still struggle with understanding circuits, which requires multi-level reasoning, particularly when involving circuit topologies. This circuit-specific benchmark highlights LLMs' limitations, offering valuable insights for advancing their application in analog integrated circuit design.

Yu-Jhe Li, Yan Xu, Rawal Khirodkar et al.

We tackle the task of multi-view, multi-person 3D human pose estimation from a limited number of uncalibrated depth cameras. Recently, many approaches have been proposed for 3D human pose estimation from multi-view RGB cameras. However, these works (1) assume the number of RGB camera views is large enough for 3D reconstruction, (2) the cameras are calibrated, and (3) rely on ground truth 3D poses for training their regression model. In this work, we propose to leverage sparse, uncalibrated depth cameras providing RGBD video streams for 3D human pose estimation. We present a simple pipeline for Multi-View Depth Human Pose Estimation (MVD-HPE) for jointly predicting the camera poses and 3D human poses without training a deep 3D human pose regression model. This framework utilizes 3D Re-ID appearance features from RGBD images to formulate more accurate correspondences (for deriving camera positions) compared to using RGB-only features. We further propose (1) depth-guided camera-pose estimation by leveraging 3D rigid transformations as guidance and (2) depth-constrained 3D human pose estimation by utilizing depth-projected 3D points as an alternative objective for optimization. In order to evaluate our proposed pipeline, we collect three video sets of RGBD videos recorded from multiple sparse-view depth cameras and ground truth 3D poses are manually annotated. Experiments show that our proposed method outperforms the current 3D human pose regression-free pipelines in terms of both camera pose estimation and 3D human pose estimation.

Yuyang Cheng, Yumiao Xu, Chaojia Yu et al.

Contemporary multi-agent systems encounter persistent challenges in cross-platform interoperability, dynamic task scheduling, and efficient resource sharing. Agents with heterogeneous implementations often lack standardized interfaces; collaboration frameworks remain brittle and hard to extend; scheduling policies are static; and inter-agent state synchronization is insufficient. We propose Hierarchical Agent Workflow (HAWK), a modular framework comprising five layers-User, Workflow, Operator, Agent, and Resource-and supported by sixteen standardized interfaces. HAWK delivers an end-to-end pipeline covering task parsing, workflow orchestration, intelligent scheduling, resource invocation, and data synchronization. At its core lies an adaptive scheduling and optimization module in the Workflow Layer, which harnesses real-time feedback and dynamic strategy adjustment to maximize utilization. The Resource Layer provides a unified abstraction over heterogeneous data sources, large models, physical devices, and third-party services&tools, simplifying cross-domain information retrieval. We demonstrate HAWK's scalability and effectiveness via CreAgentive, a multi-agent novel-generation prototype, which achieves marked gains in throughput, lowers invocation complexity, and improves system controllability. We also show how hybrid deployments of large language models integrate seamlessly within HAWK, highlighting its flexibility. Finally, we outline future research avenues-hallucination mitigation, real-time performance tuning, and enhanced cross-domain adaptability-and survey prospective applications in healthcare, government, finance, and education.

Jiahao Nick Li, Yan Xu, Tovi Grossman et al.

The progression to "Pervasive Augmented Reality" envisions easy access to multimodal information continuously. However, in many everyday scenarios, users are occupied physically, cognitively or socially. This may increase the friction to act upon the multimodal information that users encounter in the world. To reduce such friction, future interactive interfaces should intelligently provide quick access to digital actions based on users' context. To explore the range of possible digital actions, we conducted a diary study that required participants to capture and share the media that they intended to perform actions on (e.g., images or audio), along with their desired actions and other contextual information. Using this data, we generated a holistic design space of digital follow-up actions that could be performed in response to different types of multimodal sensory inputs. We then designed OmniActions, a pipeline powered by large language models (LLMs) that processes multimodal sensory inputs and predicts follow-up actions on the target information grounded in the derived design space. Using the empirical data collected in the diary study, we performed quantitative evaluations on three variations of LLM techniques (intent classification, in-context learning and finetuning) and identified the most effective technique for our task. Additionally, as an instantiation of the pipeline, we developed an interactive prototype and reported preliminary user feedback about how people perceive and react to the action predictions and its errors.

Hao Xu, Jinglong Lin, Qianyi Liu et al.

As an essential attribute of organic compounds, polarity has a profound influence on many molecular properties such as solubility and phase transition temperature. Thin layer chromatography (TLC) represents a commonly used technique for polarity measurement. However, current TLC analysis presents several problems, including the need for a large number of attempts to obtain suitable conditions, as well as irreproducibility due to non-standardization. Herein, we describe an automated experiment system for TLC analysis. This system is designed to conduct TLC analysis automatically, facilitating high-throughput experimentation by collecting large experimental data under standardized conditions. Using these datasets, machine learning (ML) methods are employed to construct surrogate models correlating organic compounds' structures and their polarity using retardation factor (Rf). The trained ML models are able to predict the Rf value curve of organic compounds with high accuracy. Furthermore, the constitutive relationship between the compound and its polarity can also be discovered through these modeling methods, and the underlying mechanism is rationalized through adsorption theories. The trained ML models not only reduce the need for empirical optimization currently required for TLC analysis, but also provide general guidelines for the selection of conditions, making TLC an easily accessible tool for the broad scientific community.

Shangbin Wu, Xu Yan, Xiaoliang Fan et al.

Learning the embeddings for urban regions from human mobility data can reveal the functionality of regions, and then enables the correlated but distinct tasks such as crime prediction. Human mobility data contains rich but abundant information, which yields to the comprehensive region embeddings for cross domain tasks. In this paper, we propose multi-graph fusion networks (MGFN) to enable the cross domain prediction tasks. First, we integrate the graphs with spatio-temporal similarity as mobility patterns through a mobility graph fusion module. Then, in the mobility pattern joint learning module, we design the multi-level cross-attention mechanism to learn the comprehensive embeddings from multiple mobility patterns based on intra-pattern and inter-pattern messages. Finally, we conduct extensive experiments on real-world urban datasets. Experimental results demonstrate that the proposed MGFN outperforms the state-of-the-art methods by up to 12.35% improvement.

Yan Xu, Yu-Jhe Li, Xinshuo Weng et al.

We address the problem of estimating the 3D pose of a network of cameras for large-environment wide-baseline scenarios, e.g., cameras for construction sites, sports stadiums, and public spaces. This task is challenging since detecting and matching the same 3D keypoint observed from two very different camera views is difficult, making standard structure-from-motion (SfM) pipelines inapplicable. In such circumstances, treating people in the scene as "keypoints" and associating them across different camera views can be an alternative method for obtaining correspondences. Based on this intuition, we propose a method that uses ideas from person re-identification (re-ID) for wide-baseline camera calibration. Our method first employs a re-ID method to associate human bounding boxes across cameras, then converts bounding box correspondences to point correspondences, and finally solves for camera pose using multi-view geometry and bundle adjustment. Since our method does not require specialized calibration targets except for visible people, it applies to situations where frequent calibration updates are required. We perform extensive experiments on datasets captured from scenes of different sizes, camera settings (indoor and outdoor), and human activities (walking, playing basketball, construction). Experiment results show that our method achieves similar performance to standard SfM methods relying on manually labeled point correspondences.

Zhaoyang Huang, Xiaokun Pan, Runsen Xu et al.

We tackle the problem of estimating flow between two images with large lighting variations. Recent learning-based flow estimation frameworks have shown remarkable performance on image pairs with small displacement and constant illuminations, but cannot work well on cases with large viewpoint change and lighting variations because of the lack of pixel-wise flow annotations for such cases. We observe that via the Structure-from-Motion (SfM) techniques, one can easily estimate relative camera poses between image pairs with large viewpoint change and lighting variations. We propose a novel weakly supervised framework LIFE to train a neural network for estimating accurate lighting-invariant flows between image pairs. Sparse correspondences are conventionally established via feature matching with descriptors encoding local image contents. However, local image contents are inevitably ambiguous and error-prone during the cross-image feature matching process, which hinders downstream tasks. We propose to guide feature matching with the flows predicted by LIFE, which addresses the ambiguous matching by utilizing abundant context information in the image pairs. We show that LIFE outperforms previous flow learning frameworks by large margins in challenging scenarios, consistently improves feature matching, and benefits downstream tasks.

Yan Xu, Yongliang Cheng

The consumer Internet of Things (IoT) have developed in recent years. Mass IoT devices are constructed to build a huge communications network. But these devices are insecure in reality, it means that the communications network are exposed by the attacker. Moreover, the IoT communication network also faces with variety of sudden errors. Therefore, it easily leads to that is vulnerable with the threat of attacker and system failure. The severe situation of IoT communication network motivates the development of new techniques to automatically detect multi-anomaly. In this paper, we propose SS-VTCN, a semi-supervised network for IoT multiple anomaly detection that works well effectively for IoT communication network. SS-VTCN is designed to capture the normal patterns of the IoT traffic data based on the distribution whether it is labeled or not by learning their representations with key techniques such as Variational Autoencoders and Temporal Convolutional Network. This network can use the encode data to predict preliminary result, and reconstruct input data to determine anomalies by the representations. Extensive evaluation experiments based on a benchmark dataset and a real consumer smart home dataset demonstrate that SS-VTCN is more suitable than supervised and unsupervised method with better performance when compared other state-of-art semi-supervised method.

Zhihao Yuan, Xu Yan, Yinghong Liao et al.

Compared with the visual grounding on 2D images, the natural-language-guided 3D object localization on point clouds is more challenging. In this paper, we propose a new model, named InstanceRefer, to achieve a superior 3D visual grounding through the grounding-by-matching strategy. In practice, our model first predicts the target category from the language descriptions using a simple language classification model. Then, based on the category, our model sifts out a small number of instance candidates (usually less than 20) from the panoptic segmentation of point clouds. Thus, the non-trivial 3D visual grounding task has been effectively re-formulated as a simplified instance-matching problem, considering that instance-level candidates are more rational than the redundant 3D object proposals. Subsequently, for each candidate, we perform the multi-level contextual inference, i.e., referring from instance attribute perception, instance-to-instance relation perception, and instance-to-background global localization perception, respectively. Eventually, the most relevant candidate is selected and localized by ranking confidence scores, which are obtained by the cooperative holistic visual-language feature matching. Experiments confirm that our method outperforms previous state-of-the-arts on ScanRefer online benchmark and Nr3D/Sr3D datasets.

Yan Xu, Zhaoyang Huang, Kwan-Yee Lin et al.

Recent learning-based LiDAR odometry methods have demonstrated their competitiveness. However, most methods still face two substantial challenges: 1) the 2D projection representation of LiDAR data cannot effectively encode 3D structures from the point clouds; 2) the needs for a large amount of labeled data for training limit the application scope of these methods. In this paper, we propose a self-supervised LiDAR odometry method, dubbed SelfVoxeLO, to tackle these two difficulties. Specifically, we propose a 3D convolution network to process the raw LiDAR data directly, which extracts features that better encode the 3D geometric patterns. To suit our network to self-supervised learning, we design several novel loss functions that utilize the inherent properties of LiDAR point clouds. Moreover, an uncertainty-aware mechanism is incorporated in the loss functions to alleviate the interference of moving objects/noises. We evaluate our method's performances on two large-scale datasets, i.e., KITTI and Apollo-SouthBay. Our method outperforms state-of-the-art unsupervised methods by 27%/32% in terms of translational/rotational errors on the KITTI dataset and also performs well on the Apollo-SouthBay dataset. By including more unlabelled training data, our method can further improve performance comparable to the supervised methods.

Mengran Fan, Tapabrata Chakrabort, Eric I-Chao Chang et al.

Fine-grained classification of microscopic image data with limited samples is an open problem in computer vision and biomedical imaging. Deep learning based vision systems mostly deal with high number of low-resolution images, whereas subtle detail in biomedical images require higher resolution. To bridge this gap, we propose a simple yet effective deep network that performs two tasks simultaneously in an end-to-end manner. First, it utilises a gated attention module that can focus on multiple key instances at high resolution without extra annotations or region proposals. Second, the global structural features and local instance features are fused for final image level classification. The result is a robust but lightweight end-to-end trainable deep network that yields state-of-the-art results in two separate fine-grained multi-instance biomedical image classification tasks: a benchmark breast cancer histology dataset and our new fungi species mycology dataset. In addition, we demonstrate the interpretability of the proposed model by visualising the concordance of the learned features with clinically relevant features.

Vivek Roy, Yan Xu, Yu-Xiong Wang et al.

We consider the few-shot classification task with an unbalanced dataset, in which some classes have sufficient training samples while other classes only have limited training samples. Recent works have proposed to solve this task by augmenting the training data of the few-shot classes using generative models with the few-shot training samples as the seeds. However, due to the limited number of the few-shot seeds, the generated samples usually have small diversity, making it difficult to train a discriminative classifier for the few-shot classes. To enrich the diversity of the generated samples, we propose to leverage the intra-class knowledge from the neighbor many-shot classes with the intuition that neighbor classes share similar statistical information. Such intra-class information is obtained with a two-step mechanism. First, a regressor trained only on the many-shot classes is used to evaluate the few-shot class means from only a few samples. Second, superclasses are clustered, and the statistical mean and feature variance of each superclass are used as transferable knowledge inherited by the children few-shot classes. Such knowledge is then used by a generator to augment the sparse training data to help the downstream classification tasks. Extensive experiments show that our method achieves state-of-the-art across different datasets and $n$-shot settings.

Yan Xu, Vivek Roy, Kris Kitani

We consider the task of re-calibrating the 3D pose of a static surveillance camera, whose pose may change due to external forces, such as birds, wind, falling objects or earthquakes. Conventionally, camera pose estimation can be solved with a PnP (Perspective-n-Point) method using 2D-to-3D feature correspondences, when 3D points are known. However, 3D point annotations are not always available or practical to obtain in real-world applications. We propose an alternative strategy for extracting 3D information to solve for camera pose by using pedestrian trajectories. We observe that 2D pedestrian trajectories indirectly contain useful 3D information that can be used for inferring camera pose. To leverage this information, we propose a data-driven approach by training a neural network (NN) regressor to model a direct mapping from 2D pedestrian trajectories projected on the image plane to 3D camera pose. We demonstrate that our regressor trained only on synthetic data can be directly applied to real data, thus eliminating the need to label any real data. We evaluate our method across six different scenes from the Town Centre Street and DUKEMTMC datasets. Our method achieves an improvement of $\sim50\%$ on both position and orientation prediction accuracy when compared to other SOTA methods.

Yan Xu, Xinge Zhu, Jianping Shi et al.

Depth completion aims to recover dense depth maps from sparse depth measurements. It is of increasing importance for autonomous driving and draws increasing attention from the vision community. Most of existing methods directly train a network to learn a mapping from sparse depth inputs to dense depth maps, which has difficulties in utilizing the 3D geometric constraints and handling the practical sensor noises. In this paper, to regularize the depth completion and improve the robustness against noise, we propose a unified CNN framework that 1) models the geometric constraints between depth and surface normal in a diffusion module and 2) predicts the confidence of sparse LiDAR measurements to mitigate the impact of noise. Specifically, our encoder-decoder backbone predicts surface normals, coarse depth and confidence of LiDAR inputs simultaneously, which are subsequently inputted into our diffusion refinement module to obtain the final completion results. Extensive experiments on KITTI depth completion dataset and NYU-Depth-V2 dataset demonstrate that our method achieves state-of-the-art performance. Further ablation study and analysis give more insights into the proposed method and demonstrate the generalization capability and stability of our model.

Jian Zhao, Yu Cheng, Yi Cheng et al.

Despite the remarkable progress in face recognition related technologies, reliably recognizing faces across ages still remains a big challenge. The appearance of a human face changes substantially over time, resulting in significant intra-class variations. As opposed to current techniques for age-invariant face recognition, which either directly extract age-invariant features for recognition, or first synthesize a face that matches target age before feature extraction, we argue that it is more desirable to perform both tasks jointly so that they can leverage each other. To this end, we propose a deep Age-Invariant Model (AIM) for face recognition in the wild with three distinct novelties. First, AIM presents a novel unified deep architecture jointly performing cross-age face synthesis and recognition in a mutual boosting way. Second, AIM achieves continuous face rejuvenation/aging with remarkable photorealistic and identity-preserving properties, avoiding the requirement of paired data and the true age of testing samples. Third, we develop effective and novel training strategies for end-to-end learning the whole deep architecture, which generates powerful age-invariant face representations explicitly disentangled from the age variation. Moreover, we propose a new large-scale Cross-Age Face Recognition (CAFR) benchmark dataset to facilitate existing efforts and push the frontiers of age-invariant face recognition research. Extensive experiments on both our CAFR and several other cross-age datasets (MORPH, CACD and FG-NET) demonstrate the superiority of the proposed AIM model over the state-of-the-arts. Benchmarking our model on one of the most popular unconstrained face recognition datasets IJB-C additionally verifies the promising generalizability of AIM in recognizing faces in the wild.

Mitko Veta, Yujing J. Heng, Nikolas Stathonikos et al.

Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is highly subjective and labor-intensive task. Previous efforts to automate tumor proliferation assessment by image analysis only focused on mitosis detection in predefined tumor regions. However, in a real-world scenario, automatic mitosis detection should be performed in whole-slide images (WSIs) and an automatic method should be able to produce a tumor proliferation score given a WSI as input. To address this, we organized the TUmor Proliferation Assessment Challenge 2016 (TUPAC16) on prediction of tumor proliferation scores from WSIs. The challenge dataset consisted of 500 training and 321 testing breast cancer histopathology WSIs. In order to ensure fair and independent evaluation, only the ground truth for the training dataset was provided to the challenge participants. The first task of the challenge was to predict mitotic scores, i.e., to reproduce the manual method of assessing tumor proliferation by a pathologist. The second task was to predict the gene expression based PAM50 proliferation scores from the WSI. The best performing automatic method for the first task achieved a quadratic-weighted Cohen's kappa score of $κ$ = 0.567, 95% CI [0.464, 0.671] between the predicted scores and the ground truth. For the second task, the predictions of the top method had a Spearman's correlation coefficient of r = 0.617, 95% CI [0.581 0.651] with the ground truth. This was the first study that investigated tumor proliferation assessment from WSIs. The achieved results are promising given the difficulty of the tasks and weakly-labelled nature of the ground truth. However, further research is needed to improve the practical utility of image analysis methods for this task.

Qianye Yang, Nannan Li, Zixu Zhao et al.

We present a cross-modality generation framework that learns to generate translated modalities from given modalities in MR images without real acquisition. Our proposed method performs NeuroImage-to-NeuroImage translation (abbreviated as N2N) by means of a deep learning model that leverages conditional generative adversarial networks (cGANs). Our framework jointly exploits the low-level features (pixel-wise information) and high-level representations (e.g. brain tumors, brain structure like gray matter, etc.) between cross modalities which are important for resolving the challenging complexity in brain structures. Our framework can serve as an auxiliary method in clinical diagnosis and has great application potential. Based on our proposed framework, we first propose a method for cross-modality registration by fusing the deformation fields to adopt the cross-modality information from translated modalities. Second, we propose an approach for MRI segmentation, translated multichannel segmentation (TMS), where given modalities, along with translated modalities, are segmented by fully convolutional networks (FCN) in a multichannel manner. Both of these two methods successfully adopt the cross-modality information to improve the performance without adding any extra data. Experiments demonstrate that our proposed framework advances the state-of-the-art on five brain MRI datasets. We also observe encouraging results in cross-modality registration and segmentation on some widely adopted brain datasets. Overall, our work can serve as an auxiliary method in clinical diagnosis and be applied to various tasks in medical fields. Keywords: image-to-image, cross-modality, registration, segmentation, brain MRI

Bo Hu, Ye Tang, Eric I-Chao Chang et al.

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly reusable for various tasks, such as cell-level classification, nuclei segmentation, and cell counting. In this paper, we propose a unified generative adversarial networks architecture with a new formulation of loss to perform robust cell-level visual representation learning in an unsupervised setting. Our model is not only label-free and easily trained but also capable of cell-level unsupervised classification with interpretable visualization, which achieves promising results in the unsupervised classification of bone marrow cellular components. Based on the proposed cell-level visual representation learning, we further develop a pipeline that exploits the varieties of cellular elements to perform histopathology image classification, the advantages of which are demonstrated on bone marrow datasets.

Siyuan Shan, Wen Yan, Xiaoqing Guo et al.

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image registration algorithms to an end-to-end convolutional neural network framework, while maintaining the unsupervised nature of image registration problems. The image-to-image integrated framework can simultaneously learn both image features and transformation matrix for registration. (2) Training with additional data without any label can further improve the registration performance by approximately 10 %. (3) The registration speed is 100x faster than traditional methods. The proposed network is easy to implement and can be trained efficiently. Experiments demonstrate that our system achieves state-of-the-art results on 2D brain registration and achieves comparable results on 2D liver registration. It can be extended to register other organs beyond liver and brain such as kidney, lung, and heart.

Xin Zhang, Weixuan Kou, Eric I-Chao Chang et al.

This paper proposes a practical approach for automatic sleep stage classification based on a multi-level feature learning framework and Recurrent Neural Network (RNN) classifier using heart rate and wrist actigraphy derived from a wearable device. The feature learning framework is designed to extract low- and mid-level features. Low-level features capture temporal and frequency domain properties and mid-level features learn compositions and structural information of signals. Since sleep staging is a sequential problem with long-term dependencies, we take advantage of RNNs with Bidirectional Long Short-Term Memory (BLSTM) architectures for sequence data learning. To simulate the actual situation of daily sleep, experiments are conducted with a resting group in which sleep is recorded in resting state, and a comprehensive group in which both resting sleep and non-resting sleep are included.We evaluate the algorithm based on an eight-fold cross validation to classify five sleep stages (W, N1, N2, N3, and REM). The proposed algorithm achieves weighted precision, recall and F1 score of 58.0%, 60.3%, and 58.2% in the resting group and 58.5%, 61.1%, and 58.5% in the comprehensive group, respectively. Various comparison experiments demonstrate the effectiveness of feature learning and BLSTM. We further explore the influence of depth and width of RNNs on performance. Our method is specially proposed for wearable devices and is expected to be applicable for long-term sleep monitoring at home. Without using too much prior domain knowledge, our method has the potential to generalize sleep disorder detection.

Lin Xiong, Jayashree Karlekar, Jian Zhao et al.

Unconstrained face recognition performance evaluations have traditionally focused on Labeled Faces in the Wild (LFW) dataset for imagery and the YouTubeFaces (YTF) dataset for videos in the last couple of years. Spectacular progress in this field has resulted in saturation on verification and identification accuracies for those benchmark datasets. In this paper, we propose a unified learning framework named Transferred Deep Feature Fusion (TDFF) targeting at the new IARPA Janus Benchmark A (IJB-A) face recognition dataset released by NIST face challenge. The IJB-A dataset includes real-world unconstrained faces from 500 subjects with full pose and illumination variations which are much harder than the LFW and YTF datasets. Inspired by transfer learning, we train two advanced deep convolutional neural networks (DCNN) with two different large datasets in source domain, respectively. By exploring the complementarity of two distinct DCNNs, deep feature fusion is utilized after feature extraction in target domain. Then, template specific linear SVMs is adopted to enhance the discrimination of framework. Finally, multiple matching scores corresponding different templates are merged as the final results. This simple unified framework exhibits excellent performance on IJB-A dataset. Based on the proposed approach, we have submitted our IJB-A results to National Institute of Standards and Technology (NIST) for official evaluation. Moreover, by introducing new data and advanced neural architecture, our method outperforms the state-of-the-art by a wide margin on IJB-A dataset.

Yan Xu, Zhengyang Shen, Xin Zhang et al.

This paper proposes a multi-level feature learning framework for human action recognition using a single body-worn inertial sensor. The framework consists of three phases, respectively designed to analyze signal-based (low-level), components (mid-level) and semantic (high-level) information. Low-level features capture the time and frequency domain property while mid-level representations learn the composition of the action. The Max-margin Latent Pattern Learning (MLPL) method is proposed to learn high-level semantic descriptions of latent action patterns as the output of our framework. The proposed method achieves the state-of-the-art performances, 88.7%, 98.8% and 72.6% (weighted F1 score) respectively, on Skoda, WISDM and OPP datasets.

Yan Xu, Yang Li, Yipei Wang et al.

Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they must also be individually identified. Methods: We leverage the idea of image-to-image prediction in recent deep learning by designing an algorithm that automatically exploits and fuses complex multichannel information - regional, location, and boundary cues - in gland histology images. Our proposed algorithm, a deep multichannel framework, alleviates heavy feature design due to the use of convolutional neural networks and is able to meet multifarious requirements by altering channels. Results: Compared with methods reported in the 2015 MICCAI Gland Segmentation Challenge and other currently prevalent instance segmentation methods, we observe state-of-the-art results based on the evaluation metrics. Conclusion: The proposed deep multichannel algorithm is an effective method for gland instance segmentation. Significance: The generalization ability of our model not only enable the algorithm to solve gland instance segmentation problems, but the channel is also alternative that can be replaced for a specific task.

Yan Xu, Siyuan Shan, Ziming Qiu et al.

In this paper, we propose an innovative end-to-end subtitle detection and recognition system for videos in East Asian languages. Our end-to-end system consists of multiple stages. Subtitles are firstly detected by a novel image operator based on the sequence information of consecutive video frames. Then, an ensemble of Convolutional Neural Networks (CNNs) trained on synthetic data is adopted for detecting and recognizing East Asian characters. Finally, a dynamic programming approach leveraging language models is applied to constitute results of the entire body of text lines. The proposed system achieves average end-to-end accuracies of 98.2% and 98.3% on 40 videos in Simplified Chinese and 40 videos in Traditional Chinese respectively, which is a significant outperformance of other existing methods. The near-perfect accuracy of our system dramatically narrows the gap between human cognitive ability and state-of-the-art algorithms used for such a task.

Yan Xu, Yang Li, Mingyuan Liu et al.

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The problem is challenging since not only do the glands need to be segmented from the complex background, they are also required to be individually identified. Here we leverage the idea of image-to-image prediction in recent deep learning by building a framework that automatically exploits and fuses complex multichannel information, regional, location and boundary patterns in gland histology images. Our proposed system, deep multichannel framework, alleviates heavy feature design due to the use of convolutional neural networks and is able to meet multifarious requirement by altering channels. Compared to methods reported in the 2015 MICCAI Gland Segmentation Challenge and other currently prevalent methods of instance segmentation, we observe state-of-the-art results based on a number of evaluation metrics.

Yan Xu, Yang Li, Mingyuan Liu et al.

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The problem is challenging since not only do the glands need to be segmented from the complex background, they are also required to be individually identified. Here we leverage the idea of image-to-image prediction in recent deep learning by building a framework that automatically exploits and fuses complex multichannel information, regional and boundary patterns, with side supervision (deep supervision on side responses) in gland histology images. Our proposed system, deep multichannel side supervision (DMCS), alleviates heavy feature design due to the use of convolutional neural networks guided by side supervision. Compared to methods reported in the 2015 MICCAI Gland Segmentation Challenge, we observe state-of-the-art results based on a number of evaluation metrics.