8.1MAApr 9Code
Enhancing Clinical Trial Patient Matching through Knowledge Augmentation and Reasoning with Multi-AgentHanwen Shi, Jin Zhang, Kunpeng Zhang
Matching patients effectively and efficiently for clinical trials is a significant challenge due to the complexity and variability of patient profiles and trial criteria. This paper introduces \textbf{Multi-Agent for Knowledge Augmentation and Reasoning (MAKAR)}, a novel multi-agent system that enhances patient-trial matching by integrating criterion augmentation with structured reasoning. MAKAR consistently improves performance by an average of 7\% across different datasets. Furthermore, it enables privacy-preserving deployment and maintains competitive performance when using smaller open-source models. Overall, MAKAR can contributes to more transparent, accurate, and privacy-conscious AI-driven patient matching.
Enhanced Seq2Seq Autoencoder via Contrastive Learning for Abstractive Text SummarizationChujie Zheng, Kunpeng Zhang, Harry Jiannan Wang et al.
In this paper, we present a denoising sequence-to-sequence (seq2seq) autoencoder via contrastive learning for abstractive text summarization. Our model adopts a standard Transformer-based architecture with a multi-layer bi-directional encoder and an auto-regressive decoder. To enhance its denoising ability, we incorporate self-supervised contrastive learning along with various sentence-level document augmentation. These two components, seq2seq autoencoder and contrastive learning, are jointly trained through fine-tuning, which improves the performance of text summarization with regard to ROUGE scores and human evaluation. We conduct experiments on two datasets and demonstrate that our model outperforms many existing benchmarks and even achieves comparable performance to the state-of-the-art abstractive systems trained with more complex architecture and extensive computation resources.