Shu Zhang

Hong-Yu Zhou, Yizhou Yu, Chengdi Wang et al.

During the diagnostic process, clinicians leverage multimodal information, such as chief complaints, medical images, and laboratory-test results. Deep-learning models for aiding diagnosis have yet to meet this requirement. Here we report a Transformer-based representation-learning model as a clinical diagnostic aid that processes multimodal input in a unified manner. Rather than learning modality-specific features, the model uses embedding layers to convert images and unstructured and structured text into visual tokens and text tokens, and bidirectional blocks with intramodal and intermodal attention to learn a holistic representation of radiographs, the unstructured chief complaint and clinical history, structured clinical information such as laboratory-test results and patient demographic information. The unified model outperformed an image-only model and non-unified multimodal diagnosis models in the identification of pulmonary diseases (by 12% and 9%, respectively) and in the prediction of adverse clinical outcomes in patients with COVID-19 (by 29% and 7%, respectively). Leveraging unified multimodal Transformer-based models may help streamline triage of patients and facilitate the clinical decision process.

Danhuai Guo, Shiyin Ge, Shu Zhang et al.

Spatial-query-by-sketch is an intuitive tool to explore human spatial knowledge about geographic environments and to support communication with scene database queries. However, traditional sketch-based spatial search methods perform insufficiently due to their inability to find hidden multi-scale map features from mental sketches. In this research, we propose a deep convolutional neural network, namely Deep Spatial Scene Network (DeepSSN), to better assess the spatial scene similarity. In DeepSSN, a triplet loss function is designed as a comprehensive distance metric to support the similarity assessment. A positive and negative example mining strategy using qualitative constraint networks in spatial reasoning is designed to ensure a consistently increasing distinction of triplets during the training process. Moreover, we develop a prototype spatial scene search system using the proposed DeepSSN, in which the users input spatial query via sketch maps and the system can automatically augment the sketch training data. The proposed model is validated using multi-source conflated map data including 131,300 labeled scene samples after data augmentation. The empirical results demonstrate that the DeepSSN outperforms baseline methods including k-nearest-neighbors, multilayer perceptron, AlexNet, DenseNet, and ResNet using mean reciprocal rank and precision metrics. This research advances geographic information retrieval studies by introducing a novel deep learning method tailored to spatial scene queries.