Jin Chen

Mou-Cheng Xu, Yu-Kun Zhou, Chen Jin et al.

We propose MisMatch, a novel consistency-driven semi-supervised segmentation framework which produces predictions that are invariant to learnt feature perturbations. MisMatch consists of an encoder and a two-head decoders. One decoder learns positive attention to the foreground regions of interest (RoI) on unlabelled images thereby generating dilated features. The other decoder learns negative attention to the foreground on the same unlabelled images thereby generating eroded features. We then apply a consistency regularisation on the paired predictions. MisMatch outperforms state-of-the-art semi-supervised methods on a CT-based pulmonary vessel segmentation task and a MRI-based brain tumour segmentation task. In addition, we show that the effectiveness of MisMatch comes from better model calibration than its supervised learning counterpart.

Md Selim, Jie Zhang, Faraneh Fathi et al.

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT scanners and customized acquisition protocols can introduce significant inconsistencies in texture features, even when assessing the same patient. This variability poses a fundamental challenge for subsequent research that relies on consistent image features. Existing CT image standardization models predominantly utilize GAN-based supervised or semi-supervised learning, but their performance remains limited. We present DiffusionCT, an innovative score-based DDPM model that operates in the latent space to transform disparate non-standard distributions into a standardized form. The architecture comprises a U-Net-based encoder-decoder, augmented by a DDPM model integrated at the bottleneck position. First, the encoder-decoder is trained independently, without embedding DDPM, to capture the latent representation of the input data. Second, the latent DDPM model is trained while keeping the encoder-decoder parameters fixed. Finally, the decoder uses the transformed latent representation to generate a standardized CT image, providing a more consistent basis for downstream analysis. Empirical tests on patient CT images indicate notable improvements in image standardization using DiffusionCT. Additionally, the model significantly reduces image noise in SPAD images, further validating the effectiveness of DiffusionCT for advanced imaging tasks.

Md. Atik Ahamed, Jin Chen, Abdullah-Al-Zubaer Imran

Medical image classification is one of the most important tasks for computer-aided diagnosis. Deep learning models, particularly convolutional neural networks, have been successfully used for disease classification from medical images, facilitated by automated feature learning. However, the diverse imaging modalities and clinical pathology make it challenging to construct generalized and robust classifications. Towards improving the model performance, we propose a novel pretraining approach, namely Forward Forward Contrastive Learning (FFCL), which leverages the Forward-Forward Algorithm in a contrastive learning framework--both locally and globally. Our experimental results on the chest X-ray dataset indicate that the proposed FFCL achieves superior performance (3.69% accuracy over ImageNet pretrained ResNet-18) over existing pretraining models in the pneumonia classification task. Moreover, extensive ablation experiments support the particular local and global contrastive pretraining design in FFCL.