Yujie Chen

Zhe Li, Yehan Qiu, Yujie Chen et al.

Clinical antimicrobial therapy requires the dynamic integration of pathogen profiles, host factors, pharmacological properties of antimicrobials, and the severity of infection.This complexity imposes fundamental limitations on the applicability of Large Language Models (LLMs) in high-stakes clinical decision-making including knowledge gaps, data privacy concerns, high deployment costs, and limited reasoning capabilities. To address these challenges, we propose KRAL (Knowledge and Reasoning Augmented Learning), a low-cost, scalable, privacy-preserving paradigm that leverages teacher-model reasoning to automatically distill knowledge and reasoning trajectories via answer-to-question reverse generation, employs heuristic learning for semi-supervised data augmentation (reducing manual annotation requirements by approximately 80%), and utilizes agentic reinforcement learning to jointly enhance medical knowledge and reasoning while optimizing computational and memory efficiency. A hierarchical evaluation employing diverse teacher-model proxies reduces assessment costs, while modular interface design facilitates seamless system updates. Experimental results demonstrate that KRAL significantly outperforms traditional Retrieval-Augmented Generation (RAG) and Supervised Fine-Tuning (SFT) methods. It improves knowledge question-answering capability (Accuracy@1 on the external open-source benchmark MEDQA increased by 1.8% vs. SFT and 3.6% vs. RAG) and reasoning capability (Pass@1 on the external benchmark PUMCH Antimicrobial increased by 27% vs. SFT and 27.2% vs. RAG), achieved at ~20% of SFT's long-term training costs. This establishes KRAL as an effective solution for enhancing local LLMs' clinical diagnostic capabilities, enabling low-cost, high-safety deployment in complex medical decision support.

Ziyi Wang, Yujie Chen, Qifan Song et al.

Low-precision training has emerged as a promising low-cost technique to enhance the training efficiency of deep neural networks without sacrificing much accuracy. Its Bayesian counterpart can further provide uncertainty quantification and improved generalization accuracy. This paper investigates low-precision sampling via Stochastic Gradient Hamiltonian Monte Carlo (SGHMC) with low-precision and full-precision gradient accumulators for both strongly log-concave and non-log-concave distributions. Theoretically, our results show that, to achieve $ε$-error in the 2-Wasserstein distance for non-log-concave distributions, low-precision SGHMC achieves quadratic improvement ($\widetilde{\mathbf{O}}\left({ε^{-2}{μ^*}^{-2}\log^2\left({ε^{-1}}\right)}\right)$) compared to the state-of-the-art low-precision sampler, Stochastic Gradient Langevin Dynamics (SGLD) ($\widetilde{\mathbf{O}}\left({ε^{-4}{λ^{*}}^{-1}\log^5\left({ε^{-1}}\right)}\right)$). Moreover, we prove that low-precision SGHMC is more robust to the quantization error compared to low-precision SGLD due to the robustness of the momentum-based update w.r.t. gradient noise. Empirically, we conduct experiments on synthetic data, and {MNIST, CIFAR-10 \& CIFAR-100} datasets, which validate our theoretical findings. Our study highlights the potential of low-precision SGHMC as an efficient and accurate sampling method for large-scale and resource-limited machine learning.

Cunhang Fan, Yujie Chen, Jun Xue et al.

In recent years, knowledge graph completion (KGC) models based on pre-trained language model (PLM) have shown promising results. However, the large number of parameters and high computational cost of PLM models pose challenges for their application in downstream tasks. This paper proposes a progressive distillation method based on masked generation features for KGC task, aiming to significantly reduce the complexity of pre-trained models. Specifically, we perform pre-distillation on PLM to obtain high-quality teacher models, and compress the PLM network to obtain multi-grade student models. However, traditional feature distillation suffers from the limitation of having a single representation of information in teacher models. To solve this problem, we propose masked generation of teacher-student features, which contain richer representation information. Furthermore, there is a significant gap in representation ability between teacher and student. Therefore, we design a progressive distillation method to distill student models at each grade level, enabling efficient knowledge transfer from teachers to students. The experimental results demonstrate that the model in the pre-distillation stage surpasses the existing state-of-the-art methods. Furthermore, in the progressive distillation stage, the model significantly reduces the model parameters while maintaining a certain level of performance. Specifically, the model parameters of the lower-grade student model are reduced by 56.7\% compared to the baseline.