Junjie Wu

Biling Wang, Michael Dohopolski, Ti Bai et al.

We evaluated the temporal performance of a deep learning (DL) based artificial intelligence (AI) model for auto segmentation in prostate radiotherapy, seeking to correlate its efficacy with changes in clinical landscapes. Our study involved 1328 prostate cancer patients who underwent definitive radiotherapy from January 2006 to August 2022 at the University of Texas Southwestern Medical Center. We trained a UNet based segmentation model on data from 2006 to 2011 and tested it on data from 2012 to 2022 to simulate real world clinical deployment. We measured the model performance using the Dice similarity coefficient (DSC), visualized the trends in contour quality using exponentially weighted moving average (EMA) curves. Additionally, we performed Wilcoxon Rank Sum Test to analyze the differences in DSC distributions across distinct periods, and multiple linear regression to investigate the impact of various clinical factors. The model exhibited peak performance in the initial phase (from 2012 to 2014) for segmenting the prostate, rectum, and bladder. However, we observed a notable decline in performance for the prostate and rectum after 2015, while bladder contour quality remained stable. Key factors that impacted the prostate contour quality included physician contouring styles, the use of various hydrogel spacer, CT scan slice thickness, MRI-guided contouring, and using intravenous (IV) contrast. Rectum contour quality was influenced by factors such as slice thickness, physician contouring styles, and the use of various hydrogel spacers. The bladder contour quality was primarily affected by using IV contrast. This study highlights the challenges in maintaining AI model performance consistency in a dynamic clinical setting. It underscores the need for continuous monitoring and updating of AI models to ensure their ongoing effectiveness and relevance in patient care.

Li Li, Peilin Cai, Ryan A. Rossi et al.

We present PersonaConvBench, a large-scale benchmark for evaluating personalized reasoning and generation in multi-turn conversations with large language models (LLMs). Unlike existing work that focuses on either personalization or conversational structure in isolation, PersonaConvBench integrates both, offering three core tasks: sentence classification, impact regression, and user-centric text generation across ten diverse Reddit-based domains. This design enables systematic analysis of how personalized conversational context shapes LLM outputs in realistic multi-user scenarios. We benchmark several commercial and open-source LLMs under a unified prompting setup and observe that incorporating personalized history yields substantial performance improvements, including a 198 percent relative gain over the best non-conversational baseline in sentiment classification. By releasing PersonaConvBench with evaluations and code, we aim to support research on LLMs that adapt to individual styles, track long-term context, and produce contextually rich, engaging responses.

Chien Van Nguyen, Xuan Shen, Ryan Aponte et al.

Small Language Models (SLMs) have become increasingly important due to their efficiency and performance to perform various language tasks with minimal computational resources, making them ideal for various settings including on-device, mobile, edge devices, among many others. In this article, we present a comprehensive survey on SLMs, focusing on their architectures, training techniques, and model compression techniques. We propose a novel taxonomy for categorizing the methods used to optimize SLMs, including model compression, pruning, and quantization techniques. We summarize the benchmark datasets that are useful for benchmarking SLMs along with the evaluation metrics commonly used. Additionally, we highlight key open challenges that remain to be addressed. Our survey aims to serve as a valuable resource for researchers and practitioners interested in developing and deploying small yet efficient language models.

Rui Wang, Junda Wu, Yu Xia et al.

Large Language Models (LLMs) are identified as being susceptible to indirect prompt injection attack, where the model undesirably deviates from user-provided instructions by executing tasks injected in the prompt context. This vulnerability stems from LLMs' inability to distinguish between data and instructions within a prompt. In this paper, we propose CachePrune that defends against this attack by identifying and pruning task-triggering neurons from the KV cache of the input prompt context. By pruning such neurons, we encourage the LLM to treat the text spans of input prompt context as only pure data, instead of any indicator of instruction following. These neurons are identified via feature attribution with a loss function induced from an upperbound of the Direct Preference Optimization (DPO) objective. We show that such a loss function enables effective feature attribution with only a few samples. We further improve on the quality of feature attribution, by exploiting an observed triggering effect in instruction following. Our approach does not impose any formatting on the original prompt or introduce extra test-time LLM calls. Experiments show that CachePrune significantly reduces attack success rates without compromising the response quality. Note: This paper aims to defend against indirect prompt injection attacks, with the goal of developing more secure and robust AI systems.