Han Hua

Zejin Wang, Jiazheng Liu, Guoqing Li et al.

Real noisy-clean pairs on a large scale are costly and difficult to obtain. Meanwhile, supervised denoisers trained on synthetic data perform poorly in practice. Self-supervised denoisers, which learn only from single noisy images, solve the data collection problem. However, self-supervised denoising methods, especially blindspot-driven ones, suffer sizable information loss during input or network design. The absence of valuable information dramatically reduces the upper bound of denoising performance. In this paper, we propose a simple yet efficient approach called Blind2Unblind to overcome the information loss in blindspot-driven denoising methods. First, we introduce a global-aware mask mapper that enables global perception and accelerates training. The mask mapper samples all pixels at blind spots on denoised volumes and maps them to the same channel, allowing the loss function to optimize all blind spots at once. Second, we propose a re-visible loss to train the denoising network and make blind spots visible. The denoiser can learn directly from raw noise images without losing information or being trapped in identity mapping. We also theoretically analyze the convergence of the re-visible loss. Extensive experiments on synthetic and real-world datasets demonstrate the superior performance of our approach compared to previous work. Code is available at https://github.com/demonsjin/Blind2Unblind.

Cheng Li, Yousuf Babiker M. Osman, Weijian Huang et al.

Multi-parametric magnetic resonance (MR) imaging is an indispensable tool in the clinic. Consequently, automatic volume-of-interest segmentation based on multi-parametric MR imaging is crucial for computer-aided disease diagnosis, treatment planning, and prognosis monitoring. Despite the extensive studies conducted in deep learning-based medical image analysis, further investigations are still required to effectively exploit the information provided by different imaging parameters. How to fuse the information is a key question in this field. Here, we propose an uncertainty-aware multi-parametric MR image feature fusion method to fully exploit the information for enhanced 3D image segmentation. Uncertainties in the independent predictions of individual modalities are utilized to guide the fusion of multi-modal image features. Extensive experiments on two datasets, one for brain tissue segmentation and the other for abdominal multi-organ segmentation, have been conducted, and our proposed method achieves better segmentation performance when compared to existing models.

Zejin Wang, Jiazheng Liu, Hao Zhai et al.

Self-supervised blind denoising for Poisson-Gaussian noise remains a challenging task. Pseudo-supervised pairs constructed from single noisy images re-corrupt the signal and degrade the performance. The visible blindspots solve the information loss in masked inputs. However, without explicitly noise sensing, mean square error as an objective function cannot adjust denoising intensities for dynamic noise levels, leading to noticeable residual noise. In this paper, we propose Blind2Sound, a simple yet effective approach to overcome residual noise in denoised images. The proposed adaptive re-visible loss senses noise levels and performs personalized denoising without noise residues while retaining the signal lossless. The theoretical analysis of intermediate medium gradients guarantees stable training, while the Cramer Gaussian loss acts as a regularization to facilitate the accurate perception of noise levels and improve the performance of the denoiser. Experiments on synthetic and real-world datasets show the superior performance of our method, especially for single-channel images.