Kuan Xu

Xinyan Wang, Ting Jia, Chongyu Wang et al. · tsinghua

Accurate identification of disease genes has consistently been one of the keys to decoding a disease's molecular mechanism. Most current approaches focus on constructing biological networks and utilizing machine learning, especially, deep learning to identify disease genes, but ignore the complex relations between entities in the biological knowledge graph. In this paper, we construct a biological knowledge graph centered on diseases and genes, and develop an end-to-end Knowledge graph completion model for Disease Gene Prediction using interactional tensor decomposition (called KDGene). KDGene introduces an interaction module between the embeddings of entities and relations to tensor decomposition, which can effectively enhance the information interaction in biological knowledge. Experimental results show that KDGene significantly outperforms state-of-the-art algorithms. Furthermore, the comprehensive biological analysis of the case of diabetes mellitus confirms KDGene's ability for identifying new and accurate candidate genes. This work proposes a scalable knowledge graph completion framework to identify disease candidate genes, from which the results are promising to provide valuable references for further wet experiments.

Kuan Xu, Kuo Yang, Hanyang Dong et al. · tsinghua

Knowledge graph completion (KGC) is one of the effective methods to identify new facts in knowledge graph. Except for a few methods based on graph network, most of KGC methods trend to be trained based on independent triples, while are difficult to take a full account of the information of global network connection contained in knowledge network. To address these issues, in this study, we propose a simple and effective Network-based Pre-training framework for knowledge graph completion (termed NetPeace), which takes into account the information of global network connection and local triple relationships in knowledge graph. Experiments show that in NetPeace framework, multiple KGC models yields consistent and significant improvements on benchmarks (e.g., 36.45% Hits@1 and 27.40% MRR improvements for TuckER on FB15k-237), especially dense knowledge graph. On the challenging low-resource task, NetPeace that benefits from the global features of KG achieves higher performance (104.03% MRR and 143.89% Hit@1 improvements at most) than original models.

Nikhil Varma Keetha, Chen Wang, Yuheng Qiu et al.

Object encoding and identification are vital for robotic tasks such as autonomous exploration, semantic scene understanding, and re-localization. Previous approaches have attempted to either track objects or generate descriptors for object identification. However, such systems are limited to a "fixed" partial object representation from a single viewpoint. In a robot exploration setup, there is a requirement for a temporally "evolving" global object representation built as the robot observes the object from multiple viewpoints. Furthermore, given the vast distribution of unknown novel objects in the real world, the object identification process must be class-agnostic. In this context, we propose a novel temporal 3D object encoding approach, dubbed AirObject, to obtain global keypoint graph-based embeddings of objects. Specifically, the global 3D object embeddings are generated using a temporal convolutional network across structural information of multiple frames obtained from a graph attention-based encoding method. We demonstrate that AirObject achieves the state-of-the-art performance for video object identification and is robust to severe occlusion, perceptual aliasing, viewpoint shift, deformation, and scale transform, outperforming the state-of-the-art single-frame and sequential descriptors. To the best of our knowledge, AirObject is one of the first temporal object encoding methods. Source code is available at https://github.com/Nik-V9/AirObject.

Kuan Xu, Zheng Yang, Lihua Xie et al.

A robust visual localization and mapping system is essential for warehouse robot navigation, as cameras offer a more cost-effective alternative to LiDAR sensors. However, existing forward-facing camera systems often encounter challenges in dynamic environments and open spaces, leading to significant performance degradation during deployment. To address these limitations, a localization system utilizing a single downward-facing camera to capture ground textures presents a promising solution. Nevertheless, existing feature-based ground-texture localization methods face difficulties when operating on surfaces with sparse features or repetitive patterns. To address this limitation, we propose GroundSLAM, a novel feature-free and ground-texture-based simultaneous localization and mapping (SLAM) system. GroundSLAM consists of three components: feature-free visual odometry, ground-texture-based loop detection and map optimization, and map reuse. Specifically, we introduce a kernel cross-correlator (KCC) for image-level pose tracking, loop detection, and map reuse to improve localization accuracy and robustness, and incorporate adaptive pruning strategies to enhance efficiency. Due to these specific designs, GroundSLAM is able to deliver efficient and stable localization across various ground surfaces such as those with sparse features and repetitive patterns. To advance research in this area, we introduce the first ground-texture dataset with precise ground-truth poses, consisting of 131k images collected from 10 kinds of indoor and outdoor ground surfaces. Extensive experimental results show that GroundSLAM outperforms state-of-the-art methods for both indoor and outdoor localization. We release our code and dataset at https://github.com/sair-lab/GroundSLAM.

Kuan Xu, Zeyu Jiang, Haozhi Cao et al.

Scene Coordinate Regression (SCR) is a visual localization technique that utilizes deep neural networks (DNN) to directly regress 2D-3D correspondences for camera pose estimation. However, current SCR methods often face challenges in handling repetitive textures and meaningless areas due to their reliance on implicit triangulation. In this paper, we propose an efficient and accurate SCR system. Compared to existing SCR methods, we propose a unified architecture for both scene encoding and salient keypoint detection, allowing our system to prioritize the encoding of informative regions. This design significantly improves computational efficiency. Additionally, we introduce a mechanism that utilizes sequential information during both mapping and relocalization. The proposed method enhances the implicit triangulation, especially in environments with repetitive textures. Comprehensive experiments conducted across indoor and outdoor datasets demonstrate that the proposed system outperforms state-of-the-art (SOTA) SCR methods. Our single-frame relocalization mode improves the recall rate of our baseline by 6.4% and increases the running speed from 56Hz to 90Hz. Furthermore, our sequence-based mode increases the recall rate by 11% while maintaining the original efficiency.

Kuan Xu, Chen Wang, Chao Chen et al.

Object encoding and identification are crucial for many robotic tasks such as autonomous exploration and semantic relocalization. Existing works heavily rely on the tracking of detected objects but have difficulty recalling revisited objects precisely. In this paper, we propose a novel object encoding method, which is named as AirCode, based on a graph of key-points. To be robust to the number of key-points detected, we propose a feature sparse encoding and object dense encoding method to ensure that each key-point can only affect a small part of the object descriptors, leading it to be robust to viewpoint changes, scaling, occlusion, and even object deformation. In the experiments, we show that it achieves superior performance for object identification than the state-of-the-art algorithms and is able to provide reliable semantic relocalization. It is a plug-and-play module and we expect that it will play an important role in various applications.