Chao Tong

Bakht Zada, Chao Tong, Qile Su et al.

Accurate 3D medical image segmentation requires both long-range volumetric context and fine boundary preservation. CNN-based methods have limited global dependency modeling, while Transformer-based models are often computationally expensive for dense 3D inputs. Recent Mamba-based methods provide an efficient alternative, but existing volumetric designs still depend on repeated high-resolution scanning, forward-only sequential modeling, and fixed directional summation, causing high cost, scan-order bias, and suboptimal directional aggregation. We propose BiSegMamba, an efficient bidirectional tri-oriented Mamba network for 3D medical image segmentation. BiSegMamba follows a compact-to-detail design, where a progressive compacting stem (PCS) enables efficient latent-space reasoning while retaining shallow high-resolution features for reconstruction. A multi-scale spatial mixer (MSSM) captures local anatomical patterns in early stages, and the proposed bidirectional tri-oriented Ortho Mamba (Bi-ToOM) block models long-range dependencies from multiple orthogonal views using jointly processed forward and backward scan sequences. Adaptive directional fusion (ADF) learns input-dependent channel-wise weights across scan orientations, replacing fixed summation with orientation-aware fusion. Experiments on a collected carotid CTA dataset and three public benchmarks, BraTS2023, ACDC, and AMOS-CT, show that BiSegMamba generalizes well across vascular, cardiac, brain tumor, and abdominal multi-organ segmentation tasks. Compared with SegMamba-V2, BiSegMamba achieves slightly better performance on BraTS2023 and clear improvements on ACDC and the carotid dataset, while reducing computational cost by up to 77.9% FLOPs, demonstrating a strong accuracy-efficiency balance for general 3D medical image segmentation.

Zaiquan Yang, Yang Liu, Wenjia Xu et al.

Zero-shot learning (ZSL) aims to recognize unseen classes by exploiting semantic descriptions shared between seen classes and unseen classes. Current methods show that it is effective to learn visual-semantic alignment by projecting semantic embeddings into the visual space as class prototypes. However, such a projection function is only concerned with seen classes. When applied to unseen classes, the prototypes often perform suboptimally due to domain shift. In this paper, we propose to learn prototypes via placeholders, termed LPL, to eliminate the domain shift between seen and unseen classes. Specifically, we combine seen classes to hallucinate new classes which play as placeholders of the unseen classes in the visual and semantic space. Placed between seen classes, the placeholders encourage prototypes of seen classes to be highly dispersed. And more space is spared for the insertion of well-separated unseen ones. Empirically, well-separated prototypes help counteract visual-semantic misalignment caused by domain shift. Furthermore, we exploit a novel semantic-oriented fine-tuning to guarantee the semantic reliability of placeholders. Extensive experiments on five benchmark datasets demonstrate the significant performance gain of LPL over the state-of-the-art methods. Code is available at https://github.com/zaiquanyang/LPL.

Yuqi Zhang, Xiaoqian Zhang, Jiakai Wang et al.

Computational pathology (CPath) has significantly advanced the clinical practice of pathology. Despite the progress made, Multiple Instance Learning (MIL), a promising paradigm within CPath, continues to face challenges, particularly related to incomplete information utilization. Existing frameworks, such as those based on Convolutional Neural Networks (CNNs), attention, and selective scan space state sequential model (SSM), lack sufficient flexibility and scalability in fusing diverse features, and cannot effectively fuse diverse features. Additionally, current approaches do not adequately exploit order-related and order-independent features, resulting in suboptimal utilization of sequence information. To address these limitations, we propose a novel MIL framework called Mamba2MIL. Our framework utilizes the state space duality model (SSD) to model long sequences of patches of whole slide images (WSIs), which, combined with weighted feature selection, supports the fusion processing of more branching features and can be extended according to specific application needs. Moreover, we introduce a sequence transformation method tailored to varying WSI sizes, which enhances sequence-independent features while preserving local sequence information, thereby improving sequence information utilization. Extensive experiments demonstrate that Mamba2MIL surpasses state-of-the-art MIL methods. We conducted extensive experiments across multiple datasets, achieving improvements in nearly all performance metrics. Specifically, on the NSCLC dataset, Mamba2MIL achieves a binary tumor classification AUC of 0.9533 and an accuracy of 0.8794. On the BRACS dataset, it achieves a multiclass classification AUC of 0.7986 and an accuracy of 0.4981. The code is available at https://github.com/YuqiZhang-Buaa/Mamba2MIL.

Zehua Liu, Shihao Zou, Jincai Huang et al.

Transarterial chemoembolization (TACE) is a preferred treatment option for hepatocellular carcinoma and other liver malignancies, yet it remains a highly challenging procedure due to complex intra-operative vascular navigation and anatomical variability. Accurate and robust 2D-3D vessel registration is essential to guide microcatheter and instruments during TACE, enabling precise localization of vascular structures and optimal therapeutic targeting. To tackle this issue, we develop a coarse-to-fine registration strategy. First, we introduce a global alignment module, structure-aware perspective n-point (SA-PnP), to establish correspondence between 2D and 3D vessel structures. Second, we propose TempDiffReg, a temporal diffusion model that performs vessel deformation iteratively by leveraging temporal context to capture complex anatomical variations and local structural changes. We collected data from 23 patients and constructed 626 paired multi-frame samples for comprehensive evaluation. Experimental results demonstrate that the proposed method consistently outperforms state-of-the-art (SOTA) methods in both accuracy and anatomical plausibility. Specifically, our method achieves a mean squared error (MSE) of 0.63 mm and a mean absolute error (MAE) of 0.51 mm in registration accuracy, representing 66.7\% lower MSE and 17.7\% lower MAE compared to the most competitive existing approaches. It has the potential to assist less-experienced clinicians in safely and efficiently performing complex TACE procedures, ultimately enhancing both surgical outcomes and patient care. Code and data are available at: \textcolor{blue}{https://github.com/LZH970328/TempDiffReg.git}

Yuancheng Yang, Lin Yang, Xu Wang et al.

As applications of large language models (LLMs) become increasingly complex, the demand for robust complex instruction following capabilities is growing accordingly. We argue that a thorough understanding of the instruction itself, especially the latent reasoning structure embedded between the lines, is crucial for improving instruction following. Therefore we target complex instructions that involve implicit reasoning, intricate logical relations, and multi-constraint dependencies. We propose ImpRIF, a method to enhance LLMs' understanding of implicit reasoning instructions, thereby improving its ability to follow complex instructions. We formalize such instructions as verifiable reasoning graphs, enabling programmatic verification and graph-driven chain-of-thought reasoning. Based on this formulation, we synthesize large-scale single- and multi-turn data, propose fine-tuning with graph reasoning, and apply reinforcement learning to explicitly train models to reason along the graph. On five complex instruction following benchmarks, our models substantially outperform their base models. These results demonstrate that enhancing implicit reasoning capabilities can significantly improve complex instruction following.

Baoyu Liang, Qile Su, Shoutai Zhu et al.

Despite the significant impact of visual events on human cognition, understanding events in videos remains a challenging task for AI due to their complex structures, semantic hierarchies, and dynamic evolution. To address this, we propose the task of video event understanding that extracts event scripts and makes predictions with these scripts from videos. To support this task, we introduce VidEvent, a large-scale dataset containing over 23,000 well-labeled events, featuring detailed event structures, broad hierarchies, and logical relations extracted from movie recap videos. The dataset was created through a meticulous annotation process, ensuring high-quality and reliable event data. We also provide comprehensive baseline models offering detailed descriptions of their architecture and performance metrics. These models serve as benchmarks for future research, facilitating comparisons and improvements. Our analysis of VidEvent and the baseline models highlights the dataset's potential to advance video event understanding and encourages the exploration of innovative algorithms and models. The dataset and related resources are publicly available at www.videvent.top.

Qile Su, Shoutai Zhu, Shuai Zhang et al.

Script event induction, which aims to predict the subsequent event based on the context, is a challenging task in NLP, achieving remarkable success in practical applications. However, human events are mostly recorded and presented in the form of videos rather than scripts, yet there is a lack of related research in the realm of vision. To address this problem, we introduce AVEP (Action-centric Video Event Prediction), a task that distinguishes itself from existing video prediction tasks through its incorporation of more complex logic and richer semantic information. We present a large structured dataset, which consists of about $35K$ annotated videos and more than $178K$ video clips of event, built upon existing video event datasets to support this task. The dataset offers more fine-grained annotations, where the atomic unit is represented as a multimodal event argument node, providing better structured representations of video events. Due to the complexity of event structures, traditional visual models that take patches or frames as input are not well-suited for AVEP. We propose EventFormer, a node-graph hierarchical attention based video event prediction model, which can capture both the relationships between events and their arguments and the coreferencial relationships between arguments. We conducted experiments using several SOTA video prediction models as well as LVLMs on AVEP, demonstrating both the complexity of the task and the value of the dataset. Our approach outperforms all these video prediction models. We will release the dataset and code for replicating the experiments and annotations.