Li Shi

Zhirong Chou, Quan Qin, Shi Li

The emergence of foundation models in healthcare has opened new avenues for learning generalizable representations from large scale clinical data. Yet, existing approaches often struggle to reconcile the tabular and event based nature of Electronic Health Records (EHRs) with the sequential priors of natural language models. This structural mismatch limits their ability to capture longitudinal dependencies across patient encounters. We introduce SerialBEHRT, a domain aligned foundation model that extends SciBERT through additional pretraining on structured EHR sequences. SerialBEHRT is designed to encode temporal and contextual relationships among clinical events, thereby producing richer patient representations. We evaluate its effectiveness on the task of antibiotic susceptibility prediction, a clinically meaningful problem in antibiotic stewardship. Through extensive benchmarking against state of the art EHR representation strategies, we demonstrate that SerialBEHRT achieves superior and more consistent performance, highlighting the importance of temporal serialization in foundation model pretraining for healthcare.

Xiangyu Guo, Shi Li

In this paper, we consider the $k$-center/median/means clustering with outliers problems (or the $(k, z)$-center/median/means problems) in the distributed setting. Most previous distributed algorithms have their communication costs linearly depending on $z$, the number of outliers. Recently Guha et al. overcame this dependence issue by considering bi-criteria approximation algorithms that output solutions with $2z$ outliers. For the case where $z$ is large, the extra $z$ outliers discarded by the algorithms might be too large, considering that the data gathering process might be costly. In this paper, we improve the number of outliers to the best possible $(1+ε)z$, while maintaining the $O(1)$-approximation ratio and independence of communication cost on $z$. The problems we consider include the $(k, z)$-center problem, and $(k, z)$-median/means problems in Euclidean metrics. Implementation of the our algorithm for $(k, z)$-center shows that it outperforms many previous algorithms, both in terms of the communication cost and quality of the output solution.