6.3IVSep 26, 2024
PNR: Physics-informed Neural Representation for high-resolution LFM reconstructionJiayin Zhao, Zhifeng Zhao, Jiamin Wu et al.
Light field microscopy (LFM) has been widely utilized in various fields for its capability to efficiently capture high-resolution 3D scenes. Despite the rapid advancements in neural representations, there are few methods specifically tailored for microscopic scenes. Existing approaches often do not adequately address issues such as the loss of high-frequency information due to defocus and sample aberration, resulting in suboptimal performance. In addition, existing methods, including RLD, INR, and supervised U-Net, face challenges such as sensitivity to initial estimates, reliance on extensive labeled data, and low computational efficiency, all of which significantly diminish the practicality in complex biological scenarios. This paper introduces PNR (Physics-informed Neural Representation), a method for high-resolution LFM reconstruction that significantly enhances performance. Our method incorporates an unsupervised and explicit feature representation approach, resulting in a 6.1 dB improvement in PSNR than RLD. Additionally, our method employs a frequency-based training loss, enabling better recovery of high-frequency details, which leads to a reduction in LPIPS by at least half compared to SOTA methods (1.762 V.S. 3.646 of DINER). Moreover, PNR integrates a physics-informed aberration correction strategy that optimizes Zernike polynomial parameters during optimization, thereby reducing the information loss caused by aberrations and improving spatial resolution. These advancements make PNR a promising solution for long-term high-resolution biological imaging applications. Our code and dataset will be made publicly available.
13.6AINov 21, 2025
Designing Domain-Specific Agents via Hierarchical Task Abstraction MechanismKaiyu Li, Jiayu Wang, Zhi Wang et al.
LLM-driven agents, particularly those using general frameworks like ReAct or human-inspired role-playing, often struggle in specialized domains that necessitate rigorously structured workflows. Fields such as remote sensing, requiring specialized tools (e.g., correction, spectral indices calculation), and multi-step procedures (e.g., numerous intermediate products and optional steps), significantly challenge generalized approaches. To address this gap, we introduce a novel agent design framework centered on a Hierarchical Task Abstraction Mechanism (HTAM). Specifically, HTAM moves beyond emulating social roles, instead structuring multi-agent systems into a logical hierarchy that mirrors the intrinsic task-dependency graph of a given domain. This task-centric architecture thus enforces procedural correctness and decomposes complex problems into sequential layers, where each layer's sub-agents operate on the outputs of the preceding layers. We instantiate this framework as EarthAgent, a multi-agent system tailored for complex geospatial analysis. To evaluate such complex planning capabilities, we build GeoPlan-bench, a comprehensive benchmark of realistic, multi-step geospatial planning tasks. It is accompanied by a suite of carefully designed metrics to evaluate tool selection, path similarity, and logical completeness. Experiments show that EarthAgent substantially outperforms a range of established single- and multi-agent systems. Our work demonstrates that aligning agent architecture with a domain's intrinsic task structure is a critical step toward building robust and reliable specialized autonomous systems.