Yang Liu

Xilei Zhu, Liu Yang, Huiyu Duan et al.

With the development of eXtended Reality (XR), photo capturing and display technology based on head-mounted displays (HMDs) have experienced significant advancements and gained considerable attention. Egocentric spatial images and videos are emerging as a compelling form of stereoscopic XR content. The assessment for the Quality of Experience (QoE) of XR content is important to ensure a high-quality viewing experience. Different from traditional 2D images, egocentric spatial images present challenges for perceptual quality assessment due to their special shooting, processing methods, and stereoscopic characteristics. However, the corresponding image quality assessment (IQA) research for egocentric spatial images is still lacking. In this paper, we establish the Egocentric Spatial Images Quality Assessment Database (ESIQAD), the first IQA database dedicated for egocentric spatial images as far as we know. Our ESIQAD includes 500 egocentric spatial images and the corresponding mean opinion scores (MOSs) under three display modes, including 2D display, 3D-window display, and 3D-immersive display. Based on our ESIQAD, we propose a novel mamba2-based multi-stage feature fusion model, termed ESIQAnet, which predicts the perceptual quality of egocentric spatial images under the three display modes. Specifically, we first extract features from multiple visual state space duality (VSSD) blocks, then apply cross attention to fuse binocular view information and use transposed attention to further refine the features. The multi-stage features are finally concatenated and fed into a quality regression network to predict the quality score. Extensive experimental results demonstrate that the ESIQAnet outperforms 22 state-of-the-art IQA models on the ESIQAD under all three display modes. The database and code are available at https://github.com/IntMeGroup/ESIQA.

Chu Chen, Aitor Artola, Yang Liu et al.

Chemical Exchange Saturation Transfer (CEST) MRI enables molecular-level visualization of low-concentration metabolites by leveraging proton exchange dynamics. However, its clinical translation is hindered by inherent challenges: spatially varying noise arising from hardware limitations, and complex imaging protocols introduce heteroscedasticity in CEST data, perturbing the accuracy of quantitative contrast mapping such as amide proton transfer (APT) imaging. Traditional denoising methods are not designed for this complex noise and often alter the underlying information that is critical for biomedical analysis. To overcome these limitations, we propose a new Blind Adaptive Local Denoising (BALD) method. BALD exploits the self-similar nature of CEST data to derive an adaptive variance-stabilizing transform that equalizes the noise distributions across CEST pixels without prior knowledge of noise characteristics. Then, BALD performs two-stage denoising on a linear transformation of data to disentangle molecular signals from noise. A local SVD decomposition is used as a linear transform to prevent spatial and spectral denoising artifacts. We conducted extensive validation experiments on multiple phantoms and \textit{in vivo} CEST scans. In these experiments, BALD consistently outperformed state-of-the-art CEST denoisers in both denoising metrics and downstream tasks such as molecular concentration maps estimation and cancer detection.