Sangwook Kim

Jaehoon Choi, Dongki Jung, Taejae Lee et al.

We present a new pipeline for acquiring a textured mesh in the wild with a single smartphone which offers access to images, depth maps, and valid poses. Our method first introduces an RGBD-aided structure from motion, which can yield filtered depth maps and refines camera poses guided by corresponding depth. Then, we adopt the neural implicit surface reconstruction method, which allows for high-quality mesh and develops a new training process for applying a regularization provided by classical multi-view stereo methods. Moreover, we apply a differentiable rendering to fine-tune incomplete texture maps and generate textures which are perceptually closer to the original scene. Our pipeline can be applied to any common objects in the real world without the need for either in-the-lab environments or accurate mask images. We demonstrate results of captured objects with complex shapes and validate our method numerically against existing 3D reconstruction and texture mapping methods.

Yuan Gao, Sangwook Kim, Chris McIntosh

Electrocardiogram (ECG) is a widely used tool for assessing cardiac function due to its low cost and accessibility. Emergent research shows that ECGs can help make predictions on key outcomes traditionally derived from more complex modalities such as echocardiograms (ECHO), enabling the use of ECGs as a more accessible method to predict broader measurements of cardiac function. ECHO, in particular, are of great importance because they require considerable hospital resources while playing a key role in clinical cardiac assessment. To aid this use case, we introduce EchoingECG, a probabilistic student-teacher model that leverages uncertainty-aware ECG embeddings and ECHO supervision to improve ECG-based cardiac function prediction. Our approach integrates Probabilistic Cross-Modal Embeddings (PCME++), a probabilistic contrastive framework, with ECHO-CLIP, a vision-language pre-trained model trained on ECHO-text pairs, to distill ECHO knowledge into ECG representations. Through experiments and external validation, we showed that EchoingECG outperforms state-of-the-art foundation ECG models in zero-shot, few-shot, and fine-tune settings for ECHO predictions based on ECG. We also highlighted that variance estimation (enabled through our method) enhanced our understanding of model performance by identifying underlying regions of uncertainty within ECGs. The code is available: https://github.com/mcintoshML/EchoingECG.

Sungphill Moon, Hyeontae Son, Dongcheol Hur et al.

Despite the progress of learning-based methods for 6D object pose estimation, the trade-off between accuracy and scalability for novel objects still exists. Specifically, previous methods for novel objects do not make good use of the target object's 3D shape information since they focus on generalization by processing the shape indirectly, making them less effective. We present GenFlow, an approach that enables both accuracy and generalization to novel objects with the guidance of the target object's shape. Our method predicts optical flow between the rendered image and the observed image and refines the 6D pose iteratively. It boosts the performance by a constraint of the 3D shape and the generalizable geometric knowledge learned from an end-to-end differentiable system. We further improve our model by designing a cascade network architecture to exploit the multi-scale correlations and coarse-to-fine refinement. GenFlow ranked first on the unseen object pose estimation benchmarks in both the RGB and RGB-D cases. It also achieves performance competitive with existing state-of-the-art methods for the seen object pose estimation without any fine-tuning.

Jianzhong You, Yuan Gao, Sangwook Kim et al.

Computed tomography (CT) is a key imaging modality for diagnosis, yet its clinical utility is marred by high radiation exposure and long turnaround times, restricting its use for larger-scale screening. Although chest radiography (CXR) is more accessible and safer, existing CXR foundation models focus primarily on detecting diseases that are readily visible on the CXR. Recently, works have explored training disease classification models on simulated CXRs, but they remain limited to recognizing a single disease type from CT. CT foundation models have also emerged with significantly improved detection of pathologies in CT. However, the generalized application of CT-derived labels on CXR has remained illusive. In this study, we propose X2CT-CLIP, a tri-modal knowledge transfer learning framework that bridges the modality gap between CT and CXR while reducing the computational burden of model training. Our approach is the first work to enable multi-abnormality classification in CT, using CXR, by transferring knowledge from 3D CT volumes and associated radiology reports to a CXR encoder via a carefully designed tri-modal alignment mechanism in latent space. Extensive evaluations on three multi-label CT datasets demonstrate that our method outperforms state-of-the-art baselines in cross-modal retrieval, few-shot adaptation, and external validation. These results highlight the potential of CXR, enriched with knowledge derived from CT, as a viable efficient alternative for disease detection in resource-limited settings.

Sangwook Kim, Aly Khalifa, Thomas G. Purdie et al.

Deep learning-based automated contouring and treatment planning has been proven to improve the efficiency and accuracy of radiotherapy. However, conventional radiotherapy treatment planning process has the automated contouring and treatment planning as separate tasks. Moreover in deep learning (DL), the contouring and dose prediction tasks for automated treatment planning are done independently. In this study, we applied the multi-task learning (MTL) approach in order to seamlessly integrate automated contouring and voxel-based dose prediction tasks, as MTL can leverage common information between the two tasks and be able able to increase the efficiency of the automated tasks. We developed our MTL framework using the two datasets: in-house prostate cancer dataset and the publicly available head and neck cancer dataset, OpenKBP. Compared to the sequential DL contouring and treatment planning tasks, our proposed method using MTL improved the mean absolute difference of dose volume histogram metrics of prostate and head and neck sites by 19.82% and 16.33%, respectively. Our MTL model for automated contouring and dose prediction tasks demonstrated enhanced dose prediction performance while maintaining or sometimes even improving the contouring accuracy. Compared to the baseline automated contouring model with the dice score coefficients of 0.818 for prostate and 0.674 for head and neck datasets, our MTL approach achieved average scores of 0.824 and 0.716 for these datasets, respectively. Our study highlights the potential of the proposed automated contouring and planning using MTL to support the development of efficient and accurate automated treatment planning for radiotherapy.

Yuan Gao, Sangwook Kim, David E Austin et al.

Medical vision-language pretraining models (VLPM) have achieved remarkable progress in fusing chest X-rays (CXR) with clinical texts, introducing image-text data binding approaches that enable zero-shot learning and downstream clinical tasks. However, the current landscape lacks the holistic integration of additional medical modalities, such as electrocardiograms (ECG). We present MEDBind (Medical Electronic patient recorD), which learns joint embeddings across CXR, ECG, and medical text. Using text data as the central anchor, MEDBind features tri-modality binding, delivering competitive performance in top-K retrieval, zero-shot, and few-shot benchmarks against established VLPM, and the ability for CXR-to-ECG zero-shot classification and retrieval. This seamless integration is achieved through combination of contrastive loss on modality-text pairs with our proposed contrastive loss function, Edge-Modality Contrastive Loss, fostering a cohesive embedding space for CXR, ECG, and text. Finally, we demonstrate that MEDBind can improve downstream tasks by directly integrating CXR and ECG embeddings into a large-language model for multimodal prompt tuning.