Cuong Q. Nguyen

Quang-Huy Nguyen, Cuong Q. Nguyen, Dung D. Le et al. · cmu, deepmind

This paper addresses the few-shot image classification problem, where the classification task is performed on unlabeled query samples given a small amount of labeled support samples only. One major challenge of the few-shot learning problem is the large variety of object visual appearances that prevents the support samples to represent that object comprehensively. This might result in a significant difference between support and query samples, therefore undermining the performance of few-shot algorithms. In this paper, we tackle the problem by proposing Few-shot Cosine Transformer (FS-CT), where the relational map between supports and queries is effectively obtained for the few-shot tasks. The FS-CT consists of two parts, a learnable prototypical embedding network to obtain categorical representations from support samples with hard cases, and a transformer encoder to effectively achieve the relational map from two different support and query samples. We introduce Cosine Attention, a more robust and stable attention module that enhances the transformer module significantly and therefore improves FS-CT performance from 5% to over 20% in accuracy compared to the default scaled dot-product mechanism. Our method performs competitive results in mini-ImageNet, CUB-200, and CIFAR-FS on 1-shot learning and 5-shot learning tasks across backbones and few-shot configurations. We also developed a custom few-shot dataset for Yoga pose recognition to demonstrate the potential of our algorithm for practical application. Our FS-CT with cosine attention is a lightweight, simple few-shot algorithm that can be applied for a wide range of applications, such as healthcare, medical, and security surveillance. The official implementation code of our Few-shot Cosine Transformer is available at https://github.com/vinuni-vishc/Few-Shot-Cosine-Transformer

Steven Shave, Richard Kasprowicz, Abdullah M. Athar et al.

The Connectivity Map (CMap) is a large publicly available database of cellular transcriptomic responses to chemical and genetic perturbations built using a standardized acquisition protocol known as the L1000 technique. Databases such as CMap provide an exciting opportunity to enrich drug discovery efforts, providing a 'known' phenotypic landscape to explore and enabling the development of state of the art techniques for enhanced information extraction and better informed decisions. Whilst multiple methods for measuring phenotypic similarity and interrogating profiles have been developed, the field is severely lacking standardized benchmarks using appropriate data splitting for training and unbiased evaluation of machine learning methods. To address this, we have developed 'Leak Proof CMap' and exemplified its application to a set of common transcriptomic and generic phenotypic similarity methods along with an exemplar triplet loss-based method. Benchmarking in three critical performance areas (compactness, distinctness, and uniqueness) is conducted using carefully crafted data splits ensuring no similar cell lines or treatments with shared or closely matching responses or mechanisms of action are present in training, validation, or test sets. This enables testing of models with unseen samples akin to exploring treatments with novel modes of action in novel patient derived cell lines. With a carefully crafted benchmark and data splitting regime in place, the tooling now exists to create performant phenotypic similarity methods for use in personalized medicine (novel cell lines) and to better augment high throughput phenotypic screening technologies with the L1000 transcriptomic technology.