Zhibin Chen

Chen Zhang, Mingxu Tao, Quzhe Huang et al. · pku

Current large language models demonstrate deficiencies in understanding low-resource languages, particularly the minority languages in China. This limitation stems from the scarcity of available pre-training data. To address this accessibility challenge, we present MC$^2$, a Multilingual Corpus of Minority Languages in China, which is the largest open-source corpus of its kind so far. MC$^2$ includes four underrepresented languages: Tibetan, Uyghur, Kazakh, and Mongolian. Notably, we focus on the less common writing systems of Kazakh and Mongolian, i.e., Kazakh Arabic script and traditional Mongolian script, respectively, which have been long neglected in previous corpus construction efforts. Recognizing the prevalence of language contamination within existing corpora, we adopt a quality-centric solution for collecting MC$^2$, prioritizing accuracy while enhancing diversity. Furthermore, we underscore the importance of attending to the multiplicity of writing systems, which is closely related to the cultural awareness of the resulting models. The MC$^2$ corpus and related models are made public to the community.

Zhibin Chen, Yansong Feng, Dongyan Zhao

Typed entailment graphs try to learn the entailment relations between predicates from text and model them as edges between predicate nodes. The construction of entailment graphs usually suffers from severe sparsity and unreliability of distributional similarity. We propose a two-stage method, Entailment Graph with Textual Entailment and Transitivity (EGT2). EGT2 learns local entailment relations by recognizing possible textual entailment between template sentences formed by typed CCG-parsed predicates. Based on the generated local graph, EGT2 then uses three novel soft transitivity constraints to consider the logical transitivity in entailment structures. Experiments on benchmark datasets show that EGT2 can well model the transitivity in entailment graph to alleviate the sparsity issue, and lead to significant improvement over current state-of-the-art methods.

Tao Li, Zilin Bian, Haozhe Lei et al.

Traditional mobility management strategies emphasize macro-level mobility oversight from traffic-sensing infrastructures, often overlooking safety risks that directly affect road users. To address this, we propose a Digital Twin-based Driver Risk-Aware Intelligent Mobility Analytics (DT-DIMA) system. The DT-DIMA system integrates real-time traffic information from pan-tilt-cameras (PTCs), synchronizes this data into a digital twin to accurately replicate the physical world, and predicts network-wide mobility and safety risks in real time. The system's innovation lies in its integration of spatial-temporal modeling, simulation, and online control modules. Tested and evaluated under normal traffic conditions and incidental situations (e.g., unexpected accidents, pre-planned work zones) in a simulated testbed in Brooklyn, New York, DT-DIMA demonstrated mean absolute percentage errors (MAPEs) ranging from 8.40% to 15.11% in estimating network-level traffic volume and MAPEs from 0.85% to 12.97% in network-level safety risk prediction. In addition, the highly accurate safety risk prediction enables PTCs to preemptively monitor road segments with high driving risks before incidents take place. Such proactive PTC surveillance creates around a 5-minute lead time in capturing traffic incidents. The DT-DIMA system enables transportation managers to understand mobility not only in terms of traffic patterns but also driver-experienced safety risks, allowing for proactive resource allocation in response to various traffic situations. To the authors' best knowledge, DT-DIMA is the first urban mobility management system that considers both mobility and safety risks based on digital twin architecture.

Zhibin Chen, Yansong Feng, Dongyan Zhao

Entailment Graphs (EGs) have been constructed based on extracted corpora as a strong and explainable form to indicate context-independent entailment relations in natural languages. However, EGs built by previous methods often suffer from the severe sparsity issues, due to limited corpora available and the long-tail phenomenon of predicate distributions. In this paper, we propose a multi-stage method, Typed Predicate-Entailment Graph Generator (TP-EGG), to tackle this problem. Given several seed predicates, TP-EGG builds the graphs by generating new predicates and detecting entailment relations among them. The generative nature of TP-EGG helps us leverage the recent advances from large pretrained language models (PLMs), while avoiding the reliance on carefully prepared corpora. Experiments on benchmark datasets show that TP-EGG can generate high-quality and scale-controllable entailment graphs, achieving significant in-domain improvement over state-of-the-art EGs and boosting the performance of down-stream inference tasks.

Anchen Sun, Elizabeth J. Franzmann, Zhibin Chen et al.

Recent advancements in image classification have demonstrated that contrastive learning (CL) can aid in further learning tasks by acquiring good feature representation from a limited number of data samples. In this paper, we applied CL to tumor transcriptomes and clinical data to learn feature representations in a low-dimensional space. We then utilized these learned features to train a classifier to categorize tumors into a high- or low-risk group of recurrence. Using data from The Cancer Genome Atlas (TCGA), we demonstrated that CL can significantly improve classification accuracy. Specifically, our CL-based classifiers achieved an area under the receiver operating characteristic curve (AUC) greater than 0.8 for 14 types of cancer, and an AUC greater than 0.9 for 2 types of cancer. We also developed CL-based Cox (CLCox) models for predicting cancer prognosis. Our CLCox models trained with the TCGA data outperformed existing methods significantly in predicting the prognosis of 19 types of cancer under consideration. The performance of CLCox models and CL-based classifiers trained with TCGA lung and prostate cancer data were validated using the data from two independent cohorts. We also show that the CLCox model trained with the whole transcriptome significantly outperforms the Cox model trained with the 21 genes of Oncotype DX that is in clinical use for breast cancer patients. CL-based classifiers and CLCox models for 19 types of cancer are publicly available and can be used to predict cancer prognosis using the RNA-seq transcriptome of an individual tumor. Python codes for model training and testing are also publicly accessible, and can be applied to train new CL-based models using gene expression data of tumors.

Yu Li, Chenyang Shao, Xinyang Liu et al.

Artificial intelligence research increasingly depends on prolonged cycles of reproduction, debugging, and iterative refinement to achieve State-Of-The-Art (SOTA) performance, creating a growing need for systems that can accelerate the full pipeline of empirical model optimization. In this work, we introduce AutoSOTA, an end-to-end automated research system that advances the latest SOTA models published in top-tier AI papers to reproducible and empirically improved new SOTA models. We formulate this problem through three tightly coupled stages: resource preparation and goal setting; experiment evaluation; and reflection and ideation. To tackle this problem, AutoSOTA adopts a multi-agent architecture with eight specialized agents that collaboratively ground papers to code and dependencies, initialize and repair execution environments, track long-horizon experiments, generate and schedule optimization ideas, and supervise validity to avoid spurious gains. We evaluate AutoSOTA on recent research papers collected from eight top-tier AI conferences under filters for code availability and execution cost. Across these papers, AutoSOTA achieves strong end-to-end performance in both automated replication and subsequent optimization. Specifically, it successfully discovers 105 new SOTA models that surpass the original reported methods, averaging approximately five hours per paper. Case studies spanning LLM, NLP, computer vision, time series, and optimization further show that the system can move beyond routine hyperparameter tuning to identify architectural innovation, algorithmic redesigns, and workflow-level improvements. These results suggest that end-to-end research automation can serve not only as a performance optimizer, but also as a new form of research infrastructure that reduces repetitive experimental burden and helps redirect human attention toward higher-level scientific creativity.

Anchen Sun, Zhibin Chen, Xiaodong Cai

The Cox Proportional Hazards (PH) model is widely used in survival analysis. Recently, artificial neural network (ANN)-based Cox-PH models have been developed. However, training these Cox models with high-dimensional features typically requires a substantial number of labeled samples containing information about time-to-event. The limited availability of labeled data for training often constrains the performance of ANN-based Cox models. To address this issue, we employed a deep semi-supervised learning (DSSL) approach to develop single- and multi-modal ANN-based Cox models based on the Mean Teacher (MT) framework, which utilizes both labeled and unlabeled data for training. We applied our model, named Cox-MT, to predict the prognosis of several types of cancer using data from The Cancer Genome Atlas (TCGA). Our single-modal Cox-MT models, utilizing TCGA RNA-seq data or whole slide images, significantly outperformed the existing ANN-based Cox model, Cox-nnet, using the same data set across four types of cancer considered. As the number of unlabeled samples increased, the performance of Cox-MT significantly improved with a given set of labeled data. Furthermore, our multi-modal Cox-MT model demonstrated considerably better performance than the single-modal model. In summary, the Cox-MT model effectively leverages both labeled and unlabeled data to significantly enhance prediction accuracy compared to existing ANN-based Cox models trained solely on labeled data.

Zhiwei Zhao, Changqing Liu, Yingguang Li et al.

In scientific and engineering applications, solving partial differential equations (PDEs) across various parameters and domains normally relies on resource-intensive numerical methods. Neural operators based on deep learning offered a promising alternative to PDEs solving by directly learning physical laws from data. However, the current neural operator methods were limited to solve PDEs on fixed domains. Expanding neural operators to solve PDEs on various domains hold significant promise in medical imaging, engineering design and manufacturing applications, where geometric and parameter changes are essential. This paper presents a novel neural operator learning framework for solving PDEs with various domains and parameters defined for physical systems, named diffeomorphism neural operator (DNO). The main idea is that a neural operator learns in a generic domain which is diffeomorphically mapped from various physics domains expressed by the same PDE. In this way, the challenge of operator learning on various domains is transformed into operator learning on the generic domain. The generalization performance of DNO on different domains can be assessed by a proposed method which evaluates the geometric similarity between a new domain and the domains of training dataset after diffeomorphism. Experiments on Darcy flow, pipe flow, airfoil flow and mechanics were carried out, where harmonic and volume parameterization were used as the diffeomorphism for 2D and 3D domains. The DNO framework demonstrated robust learning capabilities and strong generalization performance across various domains and parameters.

William Pham, Alexander Jarema, Donggyu Rim et al.

Background: Enlargement of perivascular spaces (PVS) is common in neurodegenerative disorders including cerebral small vessel disease, Alzheimer's disease, and Parkinson's disease. PVS enlargement may indicate impaired clearance pathways and there is a need for reliable PVS detection methods which are currently lacking. Aim: To optimise a widely used deep learning model, the no-new-UNet (nnU-Net), for PVS segmentation. Methods: In 30 healthy participants (mean$\pm$SD age: 50$\pm$18.9 years; 13 females), T1-weighted MRI images were acquired using three different protocols on three MRI scanners (3T Siemens Tim Trio, 3T Philips Achieva, and 7T Siemens Magnetom). PVS were manually segmented across ten axial slices in each participant. Segmentations were completed using a sparse annotation strategy. In total, 11 models were compared using various strategies for image handling, preprocessing and semi-supervised learning with pseudo-labels. Model performance was evaluated using 5-fold cross validation (5FCV). The main performance metric was the Dice Similarity Coefficient (DSC). Results: The voxel-spacing agnostic model (mean$\pm$SD DSC=64.3$\pm$3.3%) outperformed models which resampled images to a common resolution (DSC=40.5-55%). Model performance improved substantially following iterative label cleaning (DSC=85.7$\pm$1.2%). Semi-supervised learning with pseudo-labels (n=12,740) from 18 additional datasets improved the agreement between raw and predicted PVS cluster counts (Lin's concordance correlation coefficient=0.89, 95%CI=0.82-0.94). We extended the model to enable PVS segmentation in the midbrain (DSC=64.3$\pm$6.5%) and hippocampus (DSC=67.8$\pm$5%). Conclusions: Our deep learning models provide a robust and holistic framework for the automated quantification of PVS in brain MRI.

Quzhe Huang, Mingxu Tao, Chen Zhang et al.

Large Language Models (LLMs), like LLaMA, have exhibited remarkable performance across various tasks. Nevertheless, when deployed to specific domains such as law or medicine, the models still confront the challenge of a deficiency in domain-specific knowledge and an inadequate capability to leverage that knowledge to resolve domain-related problems. In this paper, we propose a new framework to adapt LLMs to specific domains and build Lawyer LLaMA, a legal domain LLM, based on this framework. Specifically, we inject domain knowledge during the continual training stage and teach the model to learn professional skills using properly designed supervised fine-tuning tasks. Moreover, to alleviate the hallucination problem during the model's generation, we add a retrieval module and extract relevant legal articles before the model answers any queries. When learning domain-specific skills, we find that experts' experience is much more useful than experiences distilled from ChatGPT, where hundreds of expert-written data outperform tens of thousands of ChatGPT-generated ones. We will release our model and data.