Yan Han

Yan Han, Chongyan Chen, Liyan Tang et al.

Chest X-ray becomes one of the most common medical diagnoses due to its noninvasiveness. The number of chest X-ray images has skyrocketed, but reading chest X-rays still have been manually performed by radiologists, which creates huge burnouts and delays. Traditionally, radiomics, as a subfield of radiology that can extract a large number of quantitative features from medical images, demonstrates its potential to facilitate medical imaging diagnosis before the deep learning era. In this paper, we develop an end-to-end framework, ChexRadiNet, that can utilize the radiomics features to improve the abnormality classification performance. Specifically, ChexRadiNet first applies a light-weight but efficient triplet-attention mechanism to classify the chest X-rays and highlight the abnormal regions. Then it uses the generated class activation map to extract radiomic features, which further guides our model to learn more robust image features. After a number of iterations and with the help of radiomic features, our framework can converge to more accurate image regions. We evaluate the ChexRadiNet framework using three public datasets: NIH ChestX-ray, CheXpert, and MIMIC-CXR. We find that ChexRadiNet outperforms the state-of-the-art on both disease detection (0.843 in AUC) and localization (0.679 in T(IoU) = 0.1). We will make the code publicly available at https://github.com/bionlplab/lung_disease_detection_amia2021, with the hope that this method can facilitate the development of automatic systems with a higher-level understanding of the radiological world.

Ajay Jaiswal, Tianhao Li, Cyprian Zander et al.

Computer-aided diagnosis plays a salient role in more accessible and accurate cardiopulmonary diseases classification and localization on chest radiography. Millions of people get affected and die due to these diseases without an accurate and timely diagnosis. Recently proposed contrastive learning heavily relies on data augmentation, especially positive data augmentation. However, generating clinically-accurate data augmentations for medical images is extremely difficult because the common data augmentation methods in computer vision, such as sharp, blur, and crop operations, can severely alter the clinical settings of medical images. In this paper, we proposed a novel and simple data augmentation method based on patient metadata and supervised knowledge to create clinically accurate positive and negative augmentations for chest X-rays. We introduce an end-to-end framework, SCALP, which extends the self-supervised contrastive approach to a supervised setting. Specifically, SCALP pulls together chest X-rays from the same patient (positive keys) and pushes apart chest X-rays from different patients (negative keys). In addition, it uses ResNet-50 along with the triplet-attention mechanism to identify cardiopulmonary diseases, and Grad-CAM++ to highlight the abnormal regions. Our extensive experiments demonstrate that SCALP outperforms existing baselines with significant margins in both classification and localization tasks. Specifically, the average classification AUCs improve from 82.8% (SOTA using DenseNet-121) to 83.9% (SCALP using ResNet-50), while the localization results improve on average by 3.7% over different IoU thresholds.

Yan Han, Chongyan Chen, Ahmed H Tewfik et al.

Chest X-ray becomes one of the most common medical diagnoses due to its noninvasiveness. The number of chest X-ray images has skyrocketed, but reading chest X-rays still have been manually performed by radiologists, which creates huge burnouts and delays. Traditionally, radiomics, as a subfield of radiology that can extract a large number of quantitative features from medical images, demonstrates its potential to facilitate medical imaging diagnosis before the deep learning era. With the rise of deep learning, the explainability of deep neural networks on chest X-ray diagnosis remains opaque. In this study, we proposed a novel framework that leverages radiomics features and contrastive learning to detect pneumonia in chest X-ray. Experiments on the RSNA Pneumonia Detection Challenge dataset show that our model achieves superior results to several state-of-the-art models (> 10% in F1-score) and increases the model's interpretability.

Gautam Krishna, Co Tran, Mason Carnahan et al.

In this paper we demonstrate predicting electroencephalograpgy (EEG) features from acoustic features using recurrent neural network (RNN) based regression model and generative adversarial network (GAN). We predict various types of EEG features from acoustic features. We compare our results with the previously studied problem on speech synthesis using EEG and our results demonstrate that EEG features can be generated from acoustic features with lower root mean square error (RMSE), normalized RMSE values compared to generating acoustic features from EEG features (ie: speech synthesis using EEG) when tested using the same data sets.

Gautam Krishna, Co Tran, Mason Carnahan et al.

In this paper we introduce various techniques to improve the performance of electroencephalography (EEG) features based continuous speech recognition (CSR) systems. A connectionist temporal classification (CTC) based automatic speech recognition (ASR) system was implemented for performing recognition. We introduce techniques to initialize the weights of the recurrent layers in the encoder of the CTC model with more meaningful weights rather than with random weights and we make use of an external language model to improve the beam search during decoding time. We finally study the problem of predicting articulatory features from EEG features in this paper.

Gautam Krishna, Co Tran, Yan Han et al.

In this paper we demonstrate continuous noisy speech recognition using connectionist temporal classification (CTC) model on limited Chinese vocabulary using electroencephalography (EEG) features with no speech signal as input and we further demonstrate single CTC model based continuous noisy speech recognition on limited joint English and Chinese vocabulary using EEG features with no speech signal as input. We demonstrate our results using various EEG feature sets recently introduced in [1] as well as we propose a new deep learning architecture in this paper which can perform continuous speech recognition using raw EEG signals on limited joint English and Chinese vocabulary.

Yan Han, Gautam Krishna, Co Tran et al.

In this paper we demonstrate that performance of a speaker verification system can be improved by concatenating electroencephalography (EEG) signal features with speech signal features or only using EEG signal features. We use state-of-the-art end-to-end deep learning model for performing speaker verification and we demonstrate our results for noisy speech. Our results indicate that EEG signals can improve the robustness of speaker verification systems, especially in noiser environment.