Zhuo He

Zhuo He, Hongjin Si, Xinwei Zhang et al.

Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This study explores the application of deep transfer learning techniques to train a predictive model for CRT response. Methods: In this study, the short-time Fourier transform (STFT) technique was employed to transform ECG signals into two-dimensional images. A transfer learning approach was then applied on the MIT-BIT ECG database to pre-train a convolutional neural network (CNN) model. The model was fine-tuned to extract relevant features from the ECG images, and then tested on our dataset of CRT patients to predict their response. Results: Seventy-one CRT patients were enrolled in this study. The transfer learning model achieved an accuracy of 72% in distinguishing responders from non-responders in the local dataset. Furthermore, the model showed good sensitivity (0.78) and specificity (0.79) in identifying CRT responders. The performance of our model outperformed clinic guidelines and traditional machine learning approaches. Conclusion: The utilization of ECG images as input and leveraging the power of transfer learning allows for improved accuracy in identifying CRT responders. This approach offers potential for enhancing patient selection and improving outcomes of CRT.

Longhui Yuan, Shuang Li, Zhuo He et al.

Test-time adaptation (TTA) adapts the pre-trained models during inference using unlabeled test data and has received a lot of research attention due to its potential practical value. Unfortunately, without any label supervision, existing TTA methods rely heavily on heuristic or empirical studies. Where to update the model always falls into suboptimal or brings more computational resource consumption. Meanwhile, there is still a significant performance gap between the TTA approaches and their supervised counterparts. Motivated by active learning, in this work, we propose the active test-time adaptation for semantic segmentation setup. Specifically, we introduce the human-in-the-loop pattern during the testing phase, which queries very few labels to facilitate predictions and model updates in an online manner. To do so, we propose a simple but effective ATASeg framework, which consists of two parts, i.e., model adapter and label annotator. Extensive experiments demonstrate that ATASeg bridges the performance gap between TTA methods and their supervised counterparts with only extremely few annotations, even one click for labeling surpasses known SOTA TTA methods by 2.6% average mIoU on ACDC benchmark. Empirical results imply that progress in either the model adapter or the label annotator will bring improvements to the ATASeg framework, giving it large research and reality potential.