Ruixuan Wang

Yaojia Zheng, Zhouwu Liu, Rong Mo et al.

Accurate automated analysis of electroencephalography (EEG) would largely help clinicians effectively monitor and diagnose patients with various brain diseases. Compared to supervised learning with labelled disease EEG data which can train a model to analyze specific diseases but would fail to monitor previously unseen statuses, anomaly detection based on only normal EEGs can detect any potential anomaly in new EEGs. Different from existing anomaly detection strategies which do not consider any property of unavailable abnormal data during model development, a task-oriented self-supervised learning approach is proposed here which makes use of available normal EEGs and expert knowledge about abnormal EEGs to train a more effective feature extractor for the subsequent development of anomaly detector. In addition, a specific two branch convolutional neural network with larger kernels is designed as the feature extractor such that it can more easily extract both larger scale and small-scale features which often appear in unavailable abnormal EEGs. The effectively designed and trained feature extractor has shown to be able to extract better feature representations from EEGs for development of anomaly detector based on normal data and future anomaly detection for new EEGs, as demonstrated on three EEG datasets. The code is available at https://github.com/ironing/EEG-AD.

Yang Yang, Zhiying Cui, Junjie Xu et al.

Deep learning has shown its human-level performance in various applications. However, current deep learning models are characterised by catastrophic forgetting of old knowledge when learning new classes. This poses a challenge particularly in intelligent diagnosis systems where initially only training data of a limited number of diseases are available. In this case, updating the intelligent system with data of new diseases would inevitably downgrade its performance on previously learned diseases. Inspired by the process of learning new knowledge in human brains, we propose a Bayesian generative model for continual learning built on a fixed pre-trained feature extractor. In this model, knowledge of each old class can be compactly represented by a collection of statistical distributions, e.g. with Gaussian mixture models, and naturally kept from forgetting in continual learning over time. Unlike existing class-incremental learning methods, the proposed approach is not sensitive to the continual learning process and can be additionally well applied to the data-incremental learning scenario. Experiments on multiple medical and natural image classification tasks showed that the proposed approach outperforms state-of-the-art approaches which even keep some images of old classes during continual learning of new classes.

Wentao Zhang, Yujun Huang, Tong Zhang et al.

Currently intelligent diagnosis systems lack the ability of continually learning to diagnose new diseases once deployed, under the condition of preserving old disease knowledge. In particular, updating an intelligent diagnosis system with training data of new diseases would cause catastrophic forgetting of old disease knowledge. To address the catastrophic forgetting issue, an Adapter-based Continual Learning framework called ACL is proposed to help effectively learn a set of new diseases at each round (or task) of continual learning, without changing the shared feature extractor. The learnable lightweight task-specific adapter(s) can be flexibly designed (e.g., two convolutional layers) and then added to the pretrained and fixed feature extractor. Together with a specially designed task-specific head which absorbs all previously learned old diseases as a single "out-of-distribution" category, task-specific adapter(s) can help the pretrained feature extractor more effectively extract discriminative features between diseases. In addition, a simple yet effective fine-tuning is applied to collaboratively fine-tune multiple task-specific heads such that outputs from different heads are comparable and consequently the appropriate classifier head can be more accurately selected during model inference. Extensive empirical evaluations on three image datasets demonstrate the superior performance of ACL in continual learning of new diseases. The source code is available at https://github.com/GiantJun/CL_Pytorch.

Jia-Xin Zhuang, Jiabin Cai, Jianguo Zhang et al.

Automated medical image classification is the key component in intelligent diagnosis systems. However, most medical image datasets contain plenty of samples of common diseases and just a handful of rare ones, leading to major class imbalances. Currently, it is an open problem in intelligent diagnosis to effectively learn from imbalanced training data. In this paper, we propose a simple yet effective framework, named \textbf{C}lass \textbf{A}ttention to \textbf{RE}gions of the lesion (CARE), to handle data imbalance issues by embedding attention into the training process of \textbf{C}onvolutional \textbf{N}eural \textbf{N}etworks (CNNs). The proposed attention module helps CNNs attend to lesion regions of rare diseases, therefore helping CNNs to learn their characteristics more effectively. In addition, this attention module works only during the training phase and does not change the architecture of the original network, so it can be directly combined with any existing CNN architecture. The CARE framework needs bounding boxes to represent the lesion regions of rare diseases. To alleviate the need for manual annotation, we further developed variants of CARE by leveraging the traditional saliency methods or a pretrained segmentation model for bounding box generation. Results show that the CARE variants with automated bounding box generation are comparable to the original CARE framework with \textit{manual} bounding box annotations. A series of experiments on an imbalanced skin image dataset and a pneumonia dataset indicates that our method can effectively help the network focus on the lesion regions of rare diseases and remarkably improves the classification performance of rare diseases.

Chenghua Zeng, Huijuan Lu, Kanghao Chen et al.

Data imbalance between common and rare diseases during model training often causes intelligent diagnosis systems to have biased predictions towards common diseases. The state-of-the-art approaches apply a two-stage learning framework to alleviate the class-imbalance issue, where the first stage focuses on training of a general feature extractor and the second stage focuses on fine-tuning the classifier head for class rebalancing. However, existing two-stage approaches do not consider the fine-grained property between different diseases, often causing the first stage less effective for medical image classification than for natural image classification tasks. In this study, we propose embedding metric learning into the first stage of the two-stage framework specially to help the feature extractor learn to extract more discriminative feature representations. Extensive experiments mainly on three medical image datasets show that the proposed approach consistently outperforms existing onestage and two-stage approaches, suggesting that metric learning can be used as an effective plug-in component in the two-stage framework for fine-grained class-imbalanced image classification tasks.

Kanghao Chen, Sijia Liu, Ruixuan Wang et al.

Current deep learning models often suffer from catastrophic forgetting of old knowledge when continually learning new knowledge. Existing strategies to alleviate this issue often fix the trade-off between keeping old knowledge (stability) and learning new knowledge (plasticity). However, the stability-plasticity trade-off during continual learning may need to be dynamically changed for better model performance. In this paper, we propose two novel ways to adaptively balance model stability and plasticity. The first one is to adaptively integrate multiple levels of old knowledge and transfer it to each block level in the new model. The second one uses prediction uncertainty of old knowledge to naturally tune the importance of learning new knowledge during model training. To our best knowledge, this is the first time to connect model prediction uncertainty and knowledge distillation for continual learning. In addition, this paper applies a modified CutMix particularly to augment the data for old knowledge, further alleviating the catastrophic forgetting issue. Extensive evaluations on the CIFAR100 and the ImageNet datasets confirmed the effectiveness of the proposed method for continual learning.

Zhuohao Sun, Yiqiao Qiu, Zhijun Tan et al.

Out-of-distribution (OOD) detection is essential when deploying neural networks in the real world. One main challenge is that neural networks often make overconfident predictions on OOD data. In this study, we propose an effective post-hoc OOD detection method based on a new feature masking strategy and a novel logit smoothing strategy. Feature masking determines the important features at the penultimate layer for each in-distribution (ID) class based on the weights of the ID class in the classifier head and masks the rest features. Logit smoothing computes the cosine similarity between the feature vector of the test sample and the prototype of the predicted ID class at the penultimate layer and uses the similarity as an adaptive temperature factor on the logit to alleviate the network's overconfidence prediction for OOD data. With these strategies, we can reduce feature activation of OOD data and enlarge the gap in OOD score between ID and OOD data. Extensive experiments on multiple standard OOD detection benchmarks demonstrate the effectiveness of our method and its compatibility with existing methods, with new state-of-the-art performance achieved from our method. The source code will be released publicly.

Jiankang Chen, Ling Deng, Zhiyong Gan et al.

Out-of-Distribution (OOD) detection is crucial when deploying machine learning models in open-world applications. The core challenge in OOD detection is mitigating the model's overconfidence on OOD data. While recent methods using auxiliary outlier datasets or synthesizing outlier features have shown promising OOD detection performance, they are limited due to costly data collection or simplified assumptions. In this paper, we propose a novel OOD detection framework FodFoM that innovatively combines multiple foundation models to generate two types of challenging fake outlier images for classifier training. The first type is based on BLIP-2's image captioning capability, CLIP's vision-language knowledge, and Stable Diffusion's image generation ability. Jointly utilizing these foundation models constructs fake outlier images which are semantically similar to but different from in-distribution (ID) images. For the second type, GroundingDINO's object detection ability is utilized to help construct pure background images by blurring foreground ID objects in ID images. The proposed framework can be flexibly combined with multiple existing OOD detection methods. Extensive empirical evaluations show that image classifiers with the help of constructed fake images can more accurately differentiate real OOD images from ID ones. New state-of-the-art OOD detection performance is achieved on multiple benchmarks. The code is available at \url{https://github.com/Cverchen/ACMMM2024-FodFoM}.

Xinhua Lu, Runhe Lai, Yanqi Wu et al.

Pre-trained vision-language models (VLMs) have advanced out-of-distribution (OOD) detection recently. However, existing CLIP-based methods often focus on learning OOD-related knowledge to improve OOD detection, showing limited generalization or reliance on external large-scale auxiliary datasets. In this study, instead of delving into the intricate OOD-related knowledge, we propose an innovative CLIP-based framework based on Forced prompt leArning (FA), designed to make full use of the In-Distribution (ID) knowledge and ultimately boost the effectiveness of OOD detection. Our key insight is to learn a prompt (i.e., forced prompt) that contains more diversified and richer descriptions of the ID classes beyond the textual semantics of class labels. Specifically, it promotes better discernment for ID images, by forcing more notable semantic similarity between ID images and the learnable forced prompt. Moreover, we introduce a forced coefficient, encouraging the forced prompt to learn more comprehensive and nuanced descriptions of the ID classes. In this way, FA is capable of achieving notable improvements in OOD detection, even when trained without any external auxiliary datasets, while maintaining an identical number of trainable parameters as CoOp. Extensive empirical evaluations confirm our method consistently outperforms current state-of-the-art methods. Code is available at https://github.com/0xFAFA/FA.

Jiantao Tan, Peixian Ma, Tong Yu et al.

Class-incremental learning requires a learning system to continually learn knowledge of new classes and meanwhile try to preserve previously learned knowledge of old classes. As current state-of-the-art methods based on Vision-Language Models (VLMs) still suffer from the issue of differentiating classes across learning tasks. Here a novel VLM-based continual learning framework for image classification is proposed. In this framework, task-specific adapters are added to the pre-trained and frozen image encoder to learn new knowledge, and a novel cross-task representation calibration strategy based on a mixture of light-weight projectors is used to help better separate all learned classes in a unified feature space, alleviating class confusion across tasks. In addition, a novel inference strategy guided by prediction uncertainty is developed to more accurately select the most appropriate image feature for class prediction. Extensive experiments on multiple datasets under various settings demonstrate the superior performance of our method compared to existing ones.

Xuchen Xie, Yiqiao Qiu, Run Lin et al.

This study focuses on incremental learning for image classification, exploring how to reduce catastrophic forgetting of all learned knowledge when access to old data is restricted due to memory or privacy constraints. The challenge of incremental learning lies in achieving an optimal balance between plasticity, the ability to learn new knowledge, and stability, the ability to retain old knowledge. Based on whether the task identifier (task-ID) of an image can be obtained during the test stage, incremental learning for image classifcation is divided into two main paradigms, which are task incremental learning (TIL) and class incremental learning (CIL). The TIL paradigm has access to the task-ID, allowing it to use multiple task-specific classification heads selected based on the task-ID. Consequently, in CIL, where the task-ID is unavailable, TIL methods must predict the task-ID to extend their application to the CIL paradigm. Our previous method for TIL adds task-specific batch normalization and classification heads incrementally. This work extends the method by predicting task-ID through an "unknown" class added to each classification head. The head with the lowest "unknown" probability is selected, enabling task-ID prediction and making the method applicable to CIL. The task-specific batch normalization (BN) modules effectively adjust the distribution of output feature maps across different tasks, enhancing the model's plasticity.Moreover, since BN has much fewer parameters compared to convolutional kernels, by only modifying the BN layers as new tasks arrive, the model can effectively manage parameter growth while ensuring stability across tasks. The innovation of this study lies in the first-time introduction of task-specific BN into CIL and verifying the feasibility of extending TIL methods to CIL through task-ID prediction with state-of-the-art performance on multiple datasets.

Fudan Zheng, Mengfei Li, Ying Wang et al.

Automatic radiology report generation is booming due to its huge application potential for the healthcare industry. However, existing computer vision and natural language processing approaches to tackle this problem are limited in two aspects. First, when extracting image features, most of them neglect multi-view reasoning in vision and model single-view structure of medical images, such as space-view or channel-view. However, clinicians rely on multi-view imaging information for comprehensive judgment in daily clinical diagnosis. Second, when generating reports, they overlook context reasoning with multi-modal information and focus on pure textual optimization utilizing retrieval-based methods. We aim to address these two issues by proposing a model that better simulates clinicians' perspectives and generates more accurate reports. Given the above limitation in feature extraction, we propose a Globally-intensive Attention (GIA) module in the medical image encoder to simulate and integrate multi-view vision perception. GIA aims to learn three types of vision perception: depth view, space view, and pixel view. On the other hand, to address the above problem in report generation, we explore how to involve multi-modal signals to generate precisely matched reports, i.e., how to integrate previously predicted words with region-aware visual content in next word prediction. Specifically, we design a Visual Knowledge-guided Decoder (VKGD), which can adaptively consider how much the model needs to rely on visual information and previously predicted text to assist next word prediction. Hence, our final Intensive Vision-guided Network (IVGN) framework includes a GIA-guided Visual Encoder and the VKGD. Experiments on two commonly-used datasets IU X-Ray and MIMIC-CXR demonstrate the superior ability of our method compared with other state-of-the-art approaches.

Jinlun Ye, Zhuohao Sun, Yiqiao Qiu et al.

Out-of-distribution (OOD) detection is crucial when deploying deep neural networks in the real world to ensure the reliability and safety of their applications. One main challenge in OOD detection is that neural network models often produce overconfident predictions on OOD data. While some methods using auxiliary OOD datasets or generating fake OOD images have shown promising OOD detection performance, they are limited by the high costs of data collection and training. In this study, we propose a novel and effective OOD detection method that utilizes local background features as fake OOD features for model training. Inspired by the observation that OOD images generally share similar background regions with ID images, the background features are extracted from ID images as simulated OOD visual representations during training based on the local invariance of convolution. Through being optimized to reduce the $L_2$-norm of these background features, the neural networks are able to alleviate the overconfidence issue on OOD data. Extensive experiments on multiple standard OOD detection benchmarks confirm the effectiveness of our method and its wide combinatorial compatibility with existing post-hoc methods, with new state-of-the-art performance achieved from our method.

Dexia Chen, Qianjie Zhu, Weibing Li et al.

Pretrained vision-language models (VLMs), such as CLIP, have shown remarkable potential in few-shot image classification and led to numerous effective transfer learning strategies. These methods leverage the pretrained knowledge of VLMs to enable effective domain adaptation while mitigating overfitting through parameter-efficient tuning or instance-based consistency constraints. However, such regularizations often neglect the geometric structure of data distribution, which may lead to distortion of the overall semantic representation. To overcome this limitation, we propose a novel fine-tuning method, Manifold-Preserving and Sculpting Tuning (MPS-Tuning). Regarding the data distribution in feature space as a semantic manifold, MPS-Tuning explicitly constrains the intrinsic geometry of this manifold while further sculpting it to enhance class separability. Specifically, MPS-Tuning preserves both macroscopic and microscopic topological structures of the original manifold by aligning Gram matrices of features before and after fine-tuning. Theoretically, this constraint is shown to approximate an upper bound of the Gromov-Wasserstein distance. Furthermore, features from the image and text modalities are paired, and pairwise similarities are optimized to enhance the manifold's class discriminability. Extensive experiments demonstrate that MPS-Tuning significantly improves model performance while effectively preserving the structure of the semantic manifold. The code will be released.

Dexia Chen, Wentao Zhang, Qianjie Zhu et al.

Vision-language models (VLMs) pre-trained on natural image and language data, such as CLIP, have exhibited significant potential in few-shot image recognition tasks, leading to development of various efficient transfer learning methods. These methods exploit inherent pre-learned knowledge in VLMs and have achieved strong performance on standard image datasets. However, their effectiveness is often limited when confronted with cross-domain tasks where imaging domains differ from natural images. To address this limitation, we propose Consistency-guided Multi-view Collaborative Optimization (CoMuCo), a novel fine-tuning strategy for VLMs. This strategy employs two functionally complementary expert modules to extract multi-view features, while incorporating prior knowledge-based consistency constraints and information geometry-based consensus mechanisms to enhance the robustness of feature learning. Additionally, a new cross-domain few-shot benchmark is established to help comprehensively evaluate methods on imaging domains distinct from natural images. Extensive empirical evaluations on both existing and newly proposed benchmarks suggest CoMuCo consistently outperforms current methods in few-shot tasks. The code and benchmark will be released.

Jia-Xin Zhuang, Wanying Tao, Jianfei Xing et al.

Deep learning models have shown their superior performance in various vision tasks. However, the lack of precisely interpreting kernels in convolutional neural networks (CNNs) is becoming one main obstacle to wide applications of deep learning models in real scenarios. Although existing interpretation methods may find certain visual patterns which are associated with the activation of a specific kernel, those visual patterns may not be specific or comprehensive enough for interpretation of a specific activation of kernel of interest. In this paper, a simple yet effective optimization method is proposed to interpret the activation of any kernel of interest in CNN models. The basic idea is to simultaneously preserve the activation of the specific kernel and suppress the activation of all other kernels at the same layer. In this way, only visual information relevant to the activation of the specific kernel is remained in the input. Consistent visual information from multiple modified inputs would help users understand what kind of features are specifically associated with specific kernel. Comprehensive evaluation shows that the proposed method can help better interpret activation of specific kernels than widely used methods, even when two kernels have very similar activation regions from the same input image.

Changhong Zhong, Zhiying Cui, Ruixuan Wang et al.

Successful continual learning of new knowledge would enable intelligent systems to recognize more and more classes of objects. However, current intelligent systems often fail to correctly recognize previously learned classes of objects when updated to learn new classes. It is widely believed that such downgraded performance is solely due to the catastrophic forgetting of previously learned knowledge. In this study, we argue that the class confusion phenomena may also play a role in downgrading the classification performance during continual learning, i.e., the high similarity between new classes and any previously learned classes would also cause the classifier to make mistakes in recognizing these old classes, even if the knowledge of these old classes is not forgotten. To alleviate the class confusion issue, we propose a discriminative distillation strategy to help the classify well learn the discriminative features between confusing classes during continual learning. Experiments on multiple natural image classification tasks support that the proposed distillation strategy, when combined with existing methods, is effective in further improving continual learning.

Zhuoyun Li, Changhong Zhong, Sijia Liu et al.

Continual learning of new knowledge over time is one desirable capability for intelligent systems to recognize more and more classes of objects. Without or with very limited amount of old data stored, an intelligent system often catastrophically forgets previously learned old knowledge when learning new knowledge. Recently, various approaches have been proposed to alleviate the catastrophic forgetting issue. However, old knowledge learned earlier is commonly less preserved than that learned more recently. In order to reduce the forgetting of particularly earlier learned old knowledge and improve the overall continual learning performance, we propose a simple yet effective fusion mechanism by including all the previously learned feature extractors into the intelligent model. In addition, a new feature extractor is included to the model when learning a new set of classes each time, and a feature extractor pruning is also applied to prevent the whole model size from growing rapidly. Experiments on multiple classification tasks show that the proposed approach can effectively reduce the forgetting of old knowledge, achieving state-of-the-art continual learning performance.

Yang Yang, Jiancong Chen, Ruixuan Wang et al.

Despite tremendous efforts, it is very challenging to generate a robust model to assist in the accurate quantification assessment of COVID-19 on chest CT images. Due to the nature of blurred boundaries, the supervised segmentation methods usually suffer from annotation biases. To support unbiased lesion localisation and to minimise the labeling costs, we propose a data-driven framework supervised by only image-level labels. The framework can explicitly separate potential lesions from original images, with the help of a generative adversarial network and a lesion-specific decoder. Experiments on two COVID-19 datasets demonstrate the effectiveness of the proposed framework and its superior performance to several existing methods.

Hongwei Li, Gongfa Jiang, Jianguo Zhang et al.

White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional network and ensemble models to automatically detect such WMH using fluid attenuation inversion recovery (FLAIR) and T1 magnetic resonance (MR) scans. The algorithm was evaluated and ranked 1 st in the WMH Segmentation Challenge at MICCAI 2017. In the evaluation stage, the implementation of the algorithm was submitted to the challenge organizers, who then independently tested it on a hidden set of 110 cases from 5 scanners. Averaged dice score, precision and robust Hausdorff distance obtained on held-out test datasets were 80%, 84% and 6.30mm respectively. These were the highest achieved in the challenge, suggesting the proposed method is the state-of-the-art. In this paper, we provide detailed descriptions and quantitative analysis on key components of the system. Furthermore, a study of cross-scanner evaluation is presented to discuss how the combination of modalities and data augmentation affect the generalization capability of the system. The adaptability of the system to different scanners and protocols is also investigated. A quantitative study is further presented to test the effect of ensemble size. Additionally, software and models of our method are made publicly available. The effectiveness and generalization capability of the proposed system show its potential for real-world clinical practice.