Lin Liu

Feiyang Jia, Zhineng Chen, Ziying Song et al.

Super-resolution (SR) aims to enhance the quality of low-resolution images and has been widely applied in medical imaging. We found that the design principles of most existing methods are influenced by SR tasks based on real-world images and do not take into account the significance of the multi-level structure in pathological images, even if they can achieve respectable objective metric evaluations. In this work, we delve into two super-resolution working paradigms and propose a novel network called CWT-Net, which leverages cross-scale image wavelet transform and Transformer architecture. Our network consists of two branches: one dedicated to learning super-resolution and the other to high-frequency wavelet features. To generate high-resolution histopathology images, the Transformer module shares and fuses features from both branches at various stages. Notably, we have designed a specialized wavelet reconstruction module to effectively enhance the wavelet domain features and enable the network to operate in different modes, allowing for the introduction of additional relevant information from cross-scale images. Our experimental results demonstrate that our model significantly outperforms state-of-the-art methods in both performance and visualization evaluations and can substantially boost the accuracy of image diagnostic networks.

Debo Cheng, Jiuyong Li, Lin Liu et al.

Latent confounders are a fundamental challenge for inferring causal effects from observational data. The instrumental variable (IV) approach is a practical way to address this challenge. Existing IV based estimators need a known IV or other strong assumptions, such as the existence of two or more IVs in the system, which limits the application of the IV approach. In this paper, we consider a relaxed requirement, which assumes there is an IV proxy in the system without knowing which variable is the proxy. We propose a Variational AutoEncoder (VAE) based disentangled representation learning method to learn an IV representation from a dataset with latent confounders and then utilise the IV representation to obtain an unbiased estimation of the causal effect from the data. Extensive experiments on synthetic and real-world data have demonstrated that the proposed algorithm outperforms the existing IV based estimators and VAE-based estimators.

Hao Chen, Lin Liu, Yu Guang Wang

Causal representation learning (CRL) has garnered increasing interests from the causal inference and artificial intelligence community, due to its capability of disentangling potentially complex data-generating mechanism into causally interpretable latent features, by leveraging the heterogeneity of modern datasets. In this paper, we further contribute to the CRL literature, by focusing on the stylized linear structural causal model over the latent features and assuming a linear mixing function that maps latent features to the observed data or measurements. Existing linear CRL methods often rely on stringent assumptions, such as accessibility to single-node interventional data or restrictive distributional constraints on latent features and exogenous measurement noise. However, these prerequisites can be challenging to satisfy in certain scenarios. In this work, we propose a novel linear CRL algorithm that, unlike most existing linear CRL methods, operates under weaker assumptions about environment heterogeneity and data-generating distributions while still recovering latent causal features up to an equivalence class. We further validate our new algorithm via synthetic experiments and an interpretability analysis of large language models (LLMs), demonstrating both its superiority over competing methods in finite samples and its potential in integrating causality into AI.