Boyu Zhang

Hanxun Jin, Enrui Zhang, Boyu Zhang et al.

Machine learning (ML) is emerging as a transformative tool for the design of architected materials, offering properties that far surpass those achievable through lab-based trial-and-error methods. However, a major challenge in current inverse design strategies is their reliance on extensive computational and/or experimental datasets, which becomes particularly problematic for designing micro-scale stochastic architected materials that exhibit nonlinear mechanical behaviors. Here, we introduce a new end-to-end scientific ML framework, leveraging deep neural operators (DeepONet), to directly learn the relationship between the complete microstructure and mechanical response of architected metamaterials from sparse but high-quality in situ experimental data. The approach facilitates the inverse design of structures tailored to specific nonlinear mechanical behaviors. Results obtained from spinodal microstructures, printed using two-photon lithography, reveal that the prediction error for mechanical responses is within a range of 5 - 10%. Our work underscores that by employing neural operators with advanced micro-mechanics experimental techniques, the design of complex micro-architected materials with desired properties becomes feasible, even in scenarios constrained by data scarcity. Our work marks a significant advancement in the field of materials-by-design, potentially heralding a new era in the discovery and development of next-generation metamaterials with unparalleled mechanical characteristics derived directly from experimental insights.

Anis Zaman, Boyu Zhang, Vincent Silenzio et al.

Anxiety disorder is one of the world's most prevalent mental health conditions, arising from complex interactions of biological and environmental factors and severely interfering one's ability to lead normal life activities. Current methods for detecting anxiety heavily rely on in-person interviews, which can be expensive, time-consuming, and blocked by social stigmas. In this work, we propose an alternative method to identify individuals with anxiety and further estimate their levels of anxiety using personal online activity histories from YouTube and the Google Search engine, platforms that are used by millions of people daily. We ran a longitudinal study and collected multiple rounds of anonymized YouTube and Google Search logs from volunteering participants, along with their clinically validated ground-truth anxiety assessment scores. We then developed explainable features that capture both the temporal and contextual aspects of online behaviors. Using those, we were able to train models that (i) identify individuals having anxiety disorder with an average F1 score of 0.83 and (ii) assess the level of anxiety by predicting the gold standard Generalized Anxiety Disorder 7-item scores (ranges from 0 to 21) with a mean square error of 1.87 based on the ubiquitous individual-level online engagement data. Our proposed anxiety assessment framework is cost-effective, time-saving, scalable, and opens the door for it to be deployed in real-world clinical settings, empowering care providers and therapists to learn about anxiety disorders of patients non-invasively at any moment in time.