Jing Xiao

Jin Huang, Bosong Huang, Weihao Yu et al.

Origin-Destination (OD) matrices record directional flow data between pairs of OD regions. The intricate spatiotemporal dependency in the matrices makes the OD matrix forecasting (ODMF) problem not only intractable but also non-trivial. However, most of the related methods are designed for very short sequence time series forecasting in specific application scenarios, which cannot meet the requirements of the variation in scenarios and forecasting length of practical applications. To address these issues, we propose a Transformer-like model named ODformer, with two salient characteristics: (i) the novel OD Attention mechanism, which captures special spatial dependencies between OD pairs of the same origin (destination), greatly improves the ability of the model to predict cross-application scenarios after combining with 2D-GCN that captures spatial dependencies between OD regions. (ii) a PeriodSparse Self-attention that effectively forecasts long sequence OD matrix series while adapting to the periodic differences in different scenarios. Generous experiments in three application backgrounds (i.e., transportation traffic, IP backbone network traffic, crowd flow) show our method outperforms the state-of-the-art methods.

Fakai Wang, Kang Zheng, Le Lu et al.

Osteoporosis is a common chronic metabolic bone disease often under-diagnosed and under-treated due to the limited access to bone mineral density (BMD) examinations, e.g. via Dual-energy X-ray Absorptiometry (DXA). This paper proposes a method to predict BMD from Chest X-ray (CXR), one of the most commonly accessible and low-cost medical imaging examinations. Our method first automatically detects Regions of Interest (ROIs) of local CXR bone structures. Then a multi-ROI deep model with transformer encoder is developed to exploit both local and global information in the chest X-ray image for accurate BMD estimation. Our method is evaluated on 13719 CXR patient cases with ground truth BMD measured by the gold standard DXA. The model predicted BMD has a strong correlation with the ground truth (Pearson correlation coefficient 0.894 on lumbar 1). When applied in osteoporosis screening, it achieves a high classification performance (average AUC of 0.968). As the first effort of using CXR scans to predict the BMD, the proposed algorithm holds strong potential for early osteoporosis screening and public health promotion.

Ke Yan, Jinzheng Cai, Dakai Jin et al.

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In principle it is possible to use landmark detection or semantic segmentation for this task, but to work well these require large numbers of labeled data for each anatomical structure and sub-structure of interest. A more universal approach would learn the intrinsic structure from unlabeled images. We introduce such an approach, called Self-supervised Anatomical eMbedding (SAM). SAM generates semantic embeddings for each image pixel that describes its anatomical location or body part. To produce such embeddings, we propose a pixel-level contrastive learning framework. A coarse-to-fine strategy ensures both global and local anatomical information are encoded. Negative sample selection strategies are designed to enhance the embedding's discriminability. Using SAM, one can label any point of interest on a template image and then locate the same body part in other images by simple nearest neighbor searching. We demonstrate the effectiveness of SAM in multiple tasks with 2D and 3D image modalities. On a chest CT dataset with 19 landmarks, SAM outperforms widely-used registration algorithms while only taking 0.23 seconds for inference. On two X-ray datasets, SAM, with only one labeled template image, surpasses supervised methods trained on 50 labeled images. We also apply SAM on whole-body follow-up lesion matching in CT and obtain an accuracy of 91%. SAM can also be applied for improving image registration and initializing CNN weights.