Xinlei Wang

Xinlei Wang, Maike Feng, Jing Qiu et al.

This paper introduces a novel approach that leverages Large Language Models (LLMs) and Generative Agents to enhance time series forecasting by reasoning across both text and time series data. With language as a medium, our method adaptively integrates social events into forecasting models, aligning news content with time series fluctuations to provide richer insights. Specifically, we utilize LLM-based agents to iteratively filter out irrelevant news and employ human-like reasoning to evaluate predictions. This enables the model to analyze complex events, such as unexpected incidents and shifts in social behavior, and continuously refine the selection logic of news and the robustness of the agent's output. By integrating selected news events with time series data, we fine-tune a pre-trained LLM to predict sequences of digits in time series. The results demonstrate significant improvements in forecasting accuracy, suggesting a potential paradigm shift in time series forecasting through the effective utilization of unstructured news data.

Younghoon Kim, Tao Wang, Danyi Xiong et al.

Early detection of cancers has been much explored due to its paramount importance in biomedical fields. Among different types of data used to answer this biological question, studies based on T cell receptors (TCRs) are under recent spotlight due to the growing appreciation of the roles of the host immunity system in tumor biology. However, the one-to-many correspondence between a patient and multiple TCR sequences hinders researchers from simply adopting classical statistical/machine learning methods. There were recent attempts to model this type of data in the context of multiple instance learning (MIL). Despite the novel application of MIL to cancer detection using TCR sequences and the demonstrated adequate performance in several tumor types, there is still room for improvement, especially for certain cancer types. Furthermore, explainable neural network models are not fully investigated for this application. In this article, we propose multiple instance neural networks based on sparse attention (MINN-SA) to enhance the performance in cancer detection and explainability. The sparse attention structure drops out uninformative instances in each bag, achieving both interpretability and better predictive performance in combination with the skip connection. Our experiments show that MINN-SA yields the highest area under the ROC curve (AUC) scores on average measured across 10 different types of cancers, compared to existing MIL approaches. Moreover, we observe from the estimated attentions that MINN-SA can identify the TCRs that are specific for tumor antigens in the same T cell repertoire.

Xiyuan Zhou, Xinlei Wang, Yirui He et al.

Large language models (LLMs) have shown strong performance on mathematical reasoning under well-posed conditions. However, real-world engineering problems require more than mathematical symbolic computation -- they need to deal with uncertainty, context, and open-ended scenarios. Existing benchmarks fail to capture these complexities. We introduce EngiBench, a hierarchical benchmark designed to evaluate LLMs on solving engineering problems. It spans three levels of increasing difficulty (foundational knowledge retrieval, multi-step contextual reasoning, and open-ended modeling) and covers diverse engineering subfields. To facilitate a deeper understanding of model performance, we systematically rewrite each problem into three controlled variants (perturbed, knowledge-enhanced, and math abstraction), enabling us to separately evaluate the model's robustness, domain-specific knowledge, and mathematical reasoning abilities. Experiment results reveal a clear performance gap across levels: models struggle more as tasks get harder, perform worse when problems are slightly changed, and fall far behind human experts on the high-level engineering tasks. These findings reveal that current LLMs still lack the high-level reasoning needed for real-world engineering, highlighting the need for future models with deeper and more reliable problem-solving capabilities. Our source code and data are available at https://github.com/EngiBench/EngiBench.

Guangming Wang, Chi Zhang, Hesheng Wang et al.

In autonomous driving, monocular sequences contain lots of information. Monocular depth estimation, camera ego-motion estimation and optical flow estimation in consecutive frames are high-profile concerns recently. By analyzing tasks above, pixels in the middle frame are modeled into three parts: the rigid region, the non-rigid region, and the occluded region. In joint unsupervised training of depth and pose, we can segment the occluded region explicitly. The occlusion information is used in unsupervised learning of depth, pose and optical flow, as the image reconstructed by depth-pose and optical flow will be invalid in occluded regions. A less-than-mean mask is designed to further exclude the mismatched pixels interfered with by motion or illumination change in the training of depth and pose networks. This method is also used to exclude some trivial mismatched pixels in the training of the optical flow network. Maximum normalization is proposed for depth smoothness term to restrain depth degradation in textureless regions. In the occluded region, as depth and camera motion can provide more reliable motion estimation, they can be used to instruct unsupervised learning of optical flow. Our experiments in KITTI dataset demonstrate that the model based on three regions, full and explicit segmentation of the occlusion region, the rigid region, and the non-rigid region with corresponding unsupervised losses can improve performance on three tasks significantly. The source code is available at: https://github.com/guangmingw/DOPlearning.

Xinlei Wang, Mingtian Tan, Jing Qiu et al.

Traditional time series analysis has long relied on pattern recognition, trained on static and well-established benchmarks. However, in real-world settings -- where policies shift, human behavior adapts, and unexpected events unfold -- effective analysis must go beyond surface-level trends to uncover the actual forces driving them. The recent rise of Large Language Models (LLMs) presents new opportunities for rethinking time series analysis by integrating multimodal inputs. However, as the use of LLMs becomes popular, we must remain cautious, asking why we use LLMs and how to exploit them effectively. Most existing LLM-based methods still employ their numerical regression ability and ignore their deeper reasoning potential. This paper argues for rethinking time series with LLMs as a reasoning task that prioritizes causal structure and explainability. This shift brings time series analysis closer to human-aligned understanding, enabling transparent and context-aware insights in complex real-world environments.