Haojie Zhu

Ya Zhou, Tianxiang Hao, Ziyi Cai et al.

Low left ventricular ejection fraction (LEF) frequently remains undetected until progression to symptomatic heart failure, underscoring the need for scalable screening strategies. Although artificial intelligence-enabled electrocardiography (AI-ECG) has shown promise, existing approaches rely solely on end-to-end black-box models with limited interpretability or on tabular systems dependent on commercial ECG measurement algorithms with suboptimal performance. We introduced ECG-based Predictor-Driven LEF (ECGPD-LEF), a structured framework that integrates foundation model-derived diagnostic probabilities with interpretable modeling for detecting LEF from ECG. Trained on the benchmark EchoNext dataset comprising 72,475 ECG-echocardiogram pairs and evaluated in predefined independent internal (n=5,442) and external (n=16,017) cohorts, our framework achieved robust discrimination for moderate LEF (internal AUROC 88.4%, F1 64.5%; external AUROC 86.8%, F1 53.6%), consistently outperforming the official end-to-end baseline provided with the benchmark across demographic and clinical subgroups. Interpretability analyses identified high-impact predictors, including normal ECG, incomplete left bundle branch block, and subendocardial injury in anterolateral leads, driving LEF risk estimation. Notably, these predictors independently enabled zero-shot-like inference without task-specific retraining (internal AUROC 75.3-81.0%; external AUROC 71.6-78.6%), indicating that ventricular dysfunction is intrinsically encoded within structured diagnostic probability representations. This framework reconciles predictive performance with mechanistic transparency, supporting scalable enhancement through additional predictors and seamless integration with existing AI-ECG systems.

Boqi Li, Haojie Zhu, Henry X. Liu

Motion prediction is critical for autonomous vehicles to effectively navigate complex environments and accurately anticipate the behaviors of other traffic participants. As autonomous driving continues to evolve, the need to assimilate new and varied driving scenarios necessitates frequent model updates through retraining. To address these demands, we introduce DECODE, a novel continual learning framework that begins with a pre-trained generalized model and incrementally develops specialized models for distinct domains. Unlike existing continual learning approaches that attempt to develop a unified model capable of generalizing across diverse scenarios, DECODE uniquely balances specialization with generalization, dynamically adjusting to real-time demands. The proposed framework leverages a hypernetwork to generate model parameters, significantly reducing storage requirements, and incorporates a normalizing flow mechanism for real-time model selection based on likelihood estimation. Furthermore, DECODE merges outputs from the most relevant specialized and generalized models using deep Bayesian uncertainty estimation techniques. This integration ensures optimal performance in familiar conditions while maintaining robustness in unfamiliar scenarios. Extensive evaluations confirm the effectiveness of the framework, achieving a notably low forgetting rate of 0.044 and an average minADE of 0.584 m, significantly surpassing traditional learning strategies and demonstrating adaptability across a wide range of driving conditions.

Jianhua Han, Meng Tian, Jiangtong Zhu et al.

Autonomous driving heavily relies on accurate and robust spatial perception. Many failures arise from inaccuracies and instability, especially in long-tail scenarios and complex interactions. However, current vision-language models are weak at spatial grounding and understanding, and VLA systems built on them therefore show limited perception and localization ability. To address these challenges, we introduce Percept-WAM, a perception-enhanced World-Awareness-Action Model that is the first to implicitly integrate 2D/3D scene understanding abilities within a single vision-language model (VLM). Instead of relying on QA-style spatial reasoning, Percept-WAM unifies 2D/3D perception tasks into World-PV and World-BEV tokens, which encode both spatial coordinates and confidence. We propose a grid-conditioned prediction mechanism for dense object perception, incorporating IoU-aware scoring and parallel autoregressive decoding, improving stability in long-tail, far-range, and small-object scenarios. Additionally, Percept-WAM leverages pretrained VLM parameters to retain general intelligence (e.g., logical reasoning) and can output perception results and trajectory control outputs directly. Experiments show that Percept-WAM matches or surpasses classical detectors and segmenters on downstream perception benchmarks, achieving 51.7/58.9 mAP on COCO 2D detection and nuScenes BEV 3D detection. When integrated with trajectory decoders, it further improves planning performance on nuScenes and NAVSIM, e.g., surpassing DiffusionDrive by 2.1 in PMDS on NAVSIM. Qualitative results further highlight its strong open-vocabulary and long-tail generalization.