Yanchao Zhang

Liuyun Jiang, Yanchao Zhang, Jinyue Guo et al.

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming manual annotations. Traditional methods augment the training set through geometric and photometric transformations; however, the generated samples remain highly correlated with the original images and lack structural diversity. To address this limitation, we propose a diffusion-based data augmentation framework capable of generating diverse and structurally plausible image-label pairs for neuron segmentation. Specifically, the framework employs a resolution-aware conditional diffusion model with multi-scale conditioning and EM resolution priors to enable voxel-level image synthesis from 3D masks. It further incorporates a biology-guided mask remodeling module that produces augmented masks with enhanced structural realism. Together, these components effectively enrich the training set and improve segmentation performance. On the AC3 and AC4 datasets under low-annotation regimes, our method improves the ARAND metric by 32.1% and 30.7%, respectively, when combined with two different post-processing methods. Our code is available at https://github.com/HeadLiuYun/NeuroDiff.

Wen Yang, Rui Wang, Yanchao Zhang

Data augmentation greatly increases the amount of data obtained based on labeled data to save on expenses and labor for data collection and labeling. We present a new approach for data augmentation called nine-dot MLS (ND-MLS). This approach is proposed based on the idea of image defor-mation. Images are deformed based on control points, which are calculated by ND-MLS. The method can generate over 2000 images for one exist-ing dataset in a short time. To verify this data augmentation method, extensive tests were performed covering 3 main tasks of computer vision, namely, classification, detection and segmentation. The results show that 1) in classification, 10 images per category were used for training, and VGGNet can obtain 92% top-1 acc on the MNIST dataset of handwritten digits by ND-MLS. In the Omniglot dataset, the few-shot accuracy usu-ally decreases with the increase in character categories. However, the ND-MLS method has stable performance and obtains 96.5 top-1 acc in Res-Net on 100 different handwritten character classification tasks; 2) in segmentation, under the premise of only ten original images, DeepLab obtains 93.5%, 85%, and 73.3% m_IOU(10) on the bottle, horse, and grass test datasets, respectively, while the cat test dataset obtains 86.7% m_IOU(10) with the SegNet model; 3) with only 10 original images from each category in object detection, YOLO v4 obtains 100% and 97.2% bottle and horse detection, respectively, while the cat dataset obtains 93.6% with YOLO v3. In summary, ND-MLS can perform well on classification, object detec-tion, and semantic segmentation tasks by using only a few data.

Liuyun Jiang, Yizhuo Lu, Yanchao Zhang et al.

Neuron segmentation is the cornerstone of reconstructing comprehensive neuronal connectomes, which is essential for deciphering the functional organization of the brain. The irregular morphology and densely intertwined structures of neurons make this task particularly challenging. Prevailing CNN-based methods often fail to resolve ambiguous boundaries due to the lack of long-range context, whereas Transformer-based methods suffer from boundary imprecision caused by the loss of voxel-level details during patch partitioning. To address these limitations, we propose NeuroMamba, a multi-perspective framework that exploits the linear complexity of Mamba to enable patch-free global modeling and synergizes this with complementary local feature modeling, thereby efficiently capturing long-range dependencies while meticulously preserving fine-grained voxel details. Specifically, we design a channel-gated Boundary Discriminative Feature Extractor (BDFE) to enhance local morphological cues. Complementing this, we introduce the Spatial Continuous Feature Extractor (SCFE), which integrates a resolution-aware scanning mechanism into the Visual Mamba architecture to adaptively model global dependencies across varying data resolutions. Finally, a cross-modulation mechanism synergistically fuses these multi-perspective features. Our method demonstrates state-of-the-art performance across four public EM datasets, validating its exceptional adaptability to both anisotropic and isotropic resolutions. The source code will be made publicly available.

Bohao Chen, Yanchao Zhang, Yanan Lv et al.

Diffusion models have recently emerged as a powerful technique in image generation, especially for image super-resolution tasks. While 2D diffusion models significantly enhance the resolution of individual images, existing diffusion-based methods for 3D volume super-resolution often struggle with structure discontinuities in axial direction and high sampling costs. In this work, we present a novel approach that leverages the 2D diffusion model and lateral continuity within the volume to enhance 3D volume electron microscopy (vEM) super-resolution. We first simulate lateral degradation with slices in the XY plane and train a 2D diffusion model to learn how to restore the degraded slices. The model is then applied slice-by-slice in the lateral direction of low-resolution volume, recovering slices while preserving inherent lateral continuity. Following this, a high-frequency-aware 3D super-resolution network is trained on the recovery lateral slice sequences to learn spatial feature transformation across slices. Finally, the network is applied to infer high-resolution volumes in the axial direction, enabling 3D super-resolution. We validate our approach through comprehensive evaluations, including image similarity assessments, resolution analysis, and performance on downstream tasks. Our results on two publicly available focused ion beam scanning electron microscopy (FIB-SEM) datasets demonstrate the robustness and practical applicability of our framework for 3D volume super-resolution.

Ghazaleh Beigi, Ruocheng Guo, Alexander Nou et al.

The overturning of the Internet Privacy Rules by the Federal Communications Commissions (FCC) in late March 2017 allows Internet Service Providers (ISPs) to collect, share and sell their customers' Web browsing data without their consent. With third-party trackers embedded on Web pages, this new rule has put user privacy under more risk. The need arises for users on their own to protect their Web browsing history from any potential adversaries. Although some available solutions such as Tor, VPN, and HTTPS can help users conceal their online activities, their use can also significantly hamper personalized online services, i.e., degraded utility. In this paper, we design an effective Web browsing history anonymization scheme, PBooster, aiming to protect users' privacy while retaining the utility of their Web browsing history. The proposed model pollutes users' Web browsing history by automatically inferring how many and what links should be added to the history while addressing the utility-privacy trade-off challenge. We conduct experiments to validate the quality of the manipulated Web browsing history and examine the robustness of the proposed approach for user privacy protection.

Ghazaleh Beigi, Kai Shu, Yanchao Zhang et al.

Social media users generate tremendous amounts of data. To better serve users, it is required to share the user-related data among researchers, advertisers and application developers. Publishing such data would raise more concerns on user privacy. To encourage data sharing and mitigate user privacy concerns, a number of anonymization and de-anonymization algorithms have been developed to help protect privacy of social media users. In this work, we propose a new adversarial attack specialized for social media data. We further provide a principled way to assess effectiveness of anonymizing different aspects of social media data. Our work sheds light on new privacy risks in social media data due to innate heterogeneity of user-generated data which require striking balance between sharing user data and protecting user privacy.

Jingchao Sun, Rui Zhang, Xiaocong Jin et al.

The plummeting cost of Bluetooth tags and the ubiquity of mobile devices are revolutionizing the traditional lost-and-found service. This paper presents SecureFind, a secure and privacy-preserving object-finding system via mobile crowdsourcing. In SecureFind, a unique Bluetooth tag is attached to every valuable object, and the owner of a lost object submits an object-finding request to many mobile users via the SecureFind service provider. Each mobile user involved searches his vicinity for the lost object on behalf of the object owner who can infer the location of his lost object based on the responses from mobile users. SecureFind is designed to ensure strong object security such that only the object owner can discover the location of his lost object as well as offering strong location privacy to mobile users involved. The high efficacy and efficiency of SecureFind are confirmed by extensive simulations.

Jingchao Sun, Rui Zhang, Jinxue Zhang et al.

Mobile authentication is indispensable for preventing unauthorized access to multi-touch mobile devices. Existing mobile authentication techniques are often cumbersome to use and also vulnerable to shoulder-surfing and smudge attacks. This paper focuses on designing, implementing, and evaluating TouchIn, a two-factor authentication system on multi-touch mobile devices. TouchIn works by letting a user draw on the touchscreen with one or multiple fingers to unlock his mobile device, and the user is authenticated based on the geometric properties of his drawn curves as well as his behavioral and physiological characteristics. TouchIn allows the user to draw on arbitrary regions on the touchscreen without looking at it. This nice sightless feature makes TouchIn very easy to use and also robust to shoulder-surfing and smudge attacks. Comprehensive experiments on Android devices confirm the high security and usability of TouchIn.