Lei Wang

Guangwei Li, Yuansen Zhang, Yinggui Wang et al.

The rapid development of large language models (LLMs) is redefining the landscape of human-computer interaction, and their integration into various user-service applications is becoming increasingly prevalent. However, transmitting user data to cloud-based LLMs presents significant risks of data breaches and unauthorized access to personal identification information. In this paper, we propose a privacy preservation pipeline for protecting privacy and sensitive information during interactions between users and LLMs in practical LLM usage scenarios. We construct SensitiveQA, the first privacy open-ended question-answering dataset. It comprises 57k interactions in Chinese and English, encompassing a diverse range of user-sensitive information within the conversations. Our proposed solution employs a multi-stage strategy aimed at preemptively securing user information while simultaneously preserving the response quality of cloud-based LLMs. Experimental validation underscores our method's efficacy in balancing privacy protection with maintaining robust interaction quality. The code and dataset are available at https://github.com/ligw1998/PRIV-QA.

Cong Sun, Zhihao Yang, Leilei Su et al.

Motivation: The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic biomedical research. Most existing methods focus only on the sentence sequence to identify these CPIs. However, the local structure of sentences and external biomedical knowledge also contain valuable information. Effective use of such information may improve the performance of CPI extraction. Results: In this paper, we propose a novel neural network-based approach to improve CPI extraction. Specifically, the approach first employs BERT to generate high-quality contextual representations of the title sequence, instance sequence, and knowledge sequence. Then, the Gaussian probability distribution is introduced to capture the local structure of the instance. Meanwhile, the attention mechanism is applied to fuse the title information and biomedical knowledge, respectively. Finally, the related representations are concatenated and fed into the softmax function to extract CPIs. We evaluate our proposed model on the CHEMPROT corpus. Our proposed model is superior in performance as compared with other state-of-the-art models. The experimental results show that the Gaussian probability distribution and external knowledge are complementary to each other. Integrating them can effectively improve the CPI extraction performance. Furthermore, the Gaussian probability distribution can effectively improve the extraction performance of sentences with overlapping relations in biomedical relation extraction tasks. Availability: Data and code are available at https://github.com/CongSun-dlut/CPI_extraction. Contact: yangzh@dlut.edu.cn, wangleibihami@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online.