Haoyu Chen

Meng Wang, Tian Lin, Lianyu Wang et al.

Failure to recognize samples from the classes unseen during training is a major limitation of artificial intelligence in the real-world implementation for recognition and classification of retinal anomalies. We established an uncertainty-inspired open-set (UIOS) model, which was trained with fundus images of 9 retinal conditions. Besides assessing the probability of each category, UIOS also calculated an uncertainty score to express its confidence. Our UIOS model with thresholding strategy achieved an F1 score of 99.55%, 97.01% and 91.91% for the internal testing set, external target categories (TC)-JSIEC dataset and TC-unseen testing set, respectively, compared to the F1 score of 92.20%, 80.69% and 64.74% by the standard AI model. Furthermore, UIOS correctly predicted high uncertainty scores, which would prompt the need for a manual check in the datasets of non-target categories retinal diseases, low-quality fundus images, and non-fundus images. UIOS provides a robust method for real-world screening of retinal anomalies.

Haoyu Chen, Jinjin Gu, Yihao Liu et al.

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of Transformer-based models that have achieved notable state-of-the-art results on various image tasks. However, deep learning-based methods often suffer from a lack of generalization ability. For example, deep models trained on Gaussian noise may perform poorly when tested on other noise distributions. To address this issue, we present a novel approach to enhance the generalization performance of denoising networks, known as masked training. Our method involves masking random pixels of the input image and reconstructing the missing information during training. We also mask out the features in the self-attention layers to avoid the impact of training-testing inconsistency. Our approach exhibits better generalization ability than other deep learning models and is directly applicable to real-world scenarios. Additionally, our interpretability analysis demonstrates the superiority of our method.

Haotian Liu, Haoyu Chen, Chenhui Pan et al.

Face forgery detection encompasses multiple critical tasks, including identifying forged images and videos and localizing manipulated regions and temporal segments. Current approaches typically employ task-specific models with independent architectures, leading to computational redundancy and ignoring potential correlations across related tasks. We introduce OmniFD, a unified framework that jointly addresses four core face forgery detection tasks within a single model, i.e., image and video classification, spatial localization, and temporal localization. Our architecture consists of three principal components: (1) a shared Swin Transformer encoder that extracts unified 4D spatiotemporal representations from both images and video inputs, (2) a cross-task interaction module with learnable queries that dynamically captures inter-task dependencies through attention-based reasoning, and (3) lightweight decoding heads that transform refined representations into corresponding predictions for all FFD tasks. Extensive experiments demonstrate OmniFD's advantage over task-specific models. Its unified design leverages multi-task learning to capture generalized representations across tasks, especially enabling fine-grained knowledge transfer that facilitates other tasks. For example, video classification accuracy improves by 4.63% when image data are incorporated. Furthermore, by unifying images, videos and the four tasks within one framework, OmniFD achieves superior performance across diverse benchmarks with high efficiency and scalability, e.g., reducing 63% model parameters and 50% training time. It establishes a practical and generalizable solution for comprehensive face forgery detection in real-world applications. The source code is made available at https://github.com/haotianll/OmniFD.

Ke Zou, Tian Lin, Xuedong Yuan et al.

Multimodality eye disease screening is crucial in ophthalmology as it integrates information from diverse sources to complement their respective performances. However, the existing methods are weak in assessing the reliability of each unimodality, and directly fusing an unreliable modality may cause screening errors. To address this issue, we introduce a novel multimodality evidential fusion pipeline for eye disease screening, EyeMoSt, which provides a measure of confidence for unimodality and elegantly integrates the multimodality information from a multi-distribution fusion perspective. Specifically, our model estimates both local uncertainty for unimodality and global uncertainty for the fusion modality to produce reliable classification results. More importantly, the proposed mixture of Student's $t$ distributions adaptively integrates different modalities to endow the model with heavy-tailed properties, increasing robustness and reliability. Our experimental findings on both public and in-house datasets show that our model is more reliable than current methods. Additionally, EyeMost has the potential ability to serve as a data quality discriminator, enabling reliable decision-making for multimodality eye disease screening.

Qingshan Hou, Yukun Zhou, Jocelyn Hui Lin Goh et al.

The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.6 million retinal images, has demonstrated high adaptability across clinical applications. Conversely, DINOv2, a general-purpose vision FM pre-trained on 142 million natural images, has shown promise in non-medical domains. However, its applicability to clinical tasks remains underexplored. To address this, we conducted head-to-head evaluations by fine-tuning RETFound and three DINOv2 models (large, base, small) for ocular disease detection and systemic disease prediction tasks, across eight standardized open-source ocular datasets, as well as the Moorfields AlzEye and the UK Biobank datasets. DINOv2-large model outperformed RETFound in detecting diabetic retinopathy (AUROC=0.850-0.952 vs 0.823-0.944, across three datasets, all P<=0.007) and multi-class eye diseases (AUROC=0.892 vs. 0.846, P<0.001). In glaucoma, DINOv2-base model outperformed RETFound (AUROC=0.958 vs 0.940, P<0.001). Conversely, RETFound achieved superior performance over all DINOv2 models in predicting heart failure, myocardial infarction, and ischaemic stroke (AUROC=0.732-0.796 vs 0.663-0.771, all P<0.001). These trends persisted even with 10% of the fine-tuning data. These findings showcase the distinct scenarios where general-purpose and domain-specific FMs excel, highlighting the importance of aligning FM selection with task-specific requirements to optimise clinical performance.

Yunlong Lin, Zixu Lin, Haoyu Chen et al.

Vision-centric perception systems struggle with unpredictable and coupled weather degradations in the wild. Current solutions are often limited, as they either depend on specific degradation priors or suffer from significant domain gaps. To enable robust and autonomous operation in real-world conditions, we propose JarvisIR, a VLM-powered agent that leverages the VLM as a controller to manage multiple expert restoration models. To further enhance system robustness, reduce hallucinations, and improve generalizability in real-world adverse weather, JarvisIR employs a novel two-stage framework consisting of supervised fine-tuning and human feedback alignment. Specifically, to address the lack of paired data in real-world scenarios, the human feedback alignment enables the VLM to be fine-tuned effectively on large-scale real-world data in an unsupervised manner. To support the training and evaluation of JarvisIR, we introduce CleanBench, a comprehensive dataset consisting of high-quality and large-scale instruction-responses pairs, including 150K synthetic entries and 80K real entries. Extensive experiments demonstrate that JarvisIR exhibits superior decision-making and restoration capabilities. Compared with existing methods, it achieves a 50% improvement in the average of all perception metrics on CleanBench-Real. Project page: https://cvpr2025-jarvisir.github.io/.

Ruibo Wang, Song Zhang, Ping Huang et al.

Accurately reconstructing road surfaces is pivotal for various applications especially in autonomous driving. This paper introduces a position encoding Multi-Layer Perceptrons (MLPs) framework to reconstruct road surfaces, with input as world coordinates x and y, and output as height, color, and semantic information. The effectiveness of this method is demonstrated through its compatibility with a variety of road height sources like vehicle camera poses, LiDAR point clouds, and SFM point clouds, robust to the semantic noise of images like sparse labels and noise semantic prediction, and fast training speed, which indicates a promising application for rendering road surfaces with semantics, particularly in applications demanding visualization of road surface, 4D labeling, and semantic groupings.

Ke Zou, Jocelyn Hui Lin Goh, Yukun Zhou et al.

Foundation models (FMs) have shown great promise in medical image analysis by improving generalization across diverse downstream tasks. In ophthalmology, several FMs have recently emerged, but there is still no clear answer to fundamental questions: Which FM performs the best? Are they equally good across different tasks? What if we combine all FMs together? To our knowledge, this is the first study to systematically evaluate both single and fused ophthalmic FMs. To address these questions, we propose FusionFM, a comprehensive evaluation suite, along with two fusion approaches to integrate different ophthalmic FMs. Our framework covers both ophthalmic disease detection (glaucoma, diabetic retinopathy, and age-related macular degeneration) and systemic disease prediction (diabetes and hypertension) based on retinal imaging. We benchmarked four state-of-the-art FMs (RETFound, VisionFM, RetiZero, and DINORET) using standardized datasets from multiple countries and evaluated their performance using AUC and F1 metrics. Our results show that DINORET and RetiZero achieve superior performance in both ophthalmic and systemic disease tasks, with RetiZero exhibiting stronger generalization on external datasets. Regarding fusion strategies, the Gating-based approach provides modest improvements in predicting glaucoma, AMD, and hypertension. Despite these advances, predicting systemic diseases, especially hypertension in external cohort remains challenging. These findings provide an evidence-based evaluation of ophthalmic FMs, highlight the benefits of model fusion, and point to strategies for enhancing their clinical applicability.

Xiaojie Xu, Xinli Xu, Sirui Chen et al.

Visual presentations are vital for effective communication. Early attempts to automate their creation using deep learning often faced issues such as poorly organized layouts, inaccurate text summarization, and a lack of image understanding, leading to mismatched visuals and text. These limitations restrict their application in formal contexts like business and scientific research. To address these challenges, we propose PreGenie, an agentic and modular framework powered by multimodal large language models (MLLMs) for generating high-quality visual presentations. PreGenie is built on the Slidev presentation framework, where slides are rendered from Markdown code. It operates in two stages: (1) Analysis and Initial Generation, which summarizes multimodal input and generates initial code, and (2) Review and Re-generation, which iteratively reviews intermediate code and rendered slides to produce final, high-quality presentations. Each stage leverages multiple MLLMs that collaborate and share information. Comprehensive experiments demonstrate that PreGenie excels in multimodal understanding, outperforming existing models in both aesthetics and content consistency, while aligning more closely with human design preferences.

Fang Kang, Yin Cao, Haoyu Chen

Recent studies in speech-driven talking face generation achieve promising results, but their reliance on fixed-driven speech limits further applications (e.g., face-voice mismatch). Thus, we extend the task to a more challenging setting: given a face image and text to speak, generating both talking face animation and its corresponding speeches. Accordingly, we propose a novel framework, Face2VoiceSync, with several novel contributions: 1) Voice-Face Alignment, ensuring generated voices match facial appearance; 2) Diversity \& Manipulation, enabling generated voice control over paralinguistic features space; 3) Efficient Training, using a lightweight VAE to bridge visual and audio large-pretrained models, with significantly fewer trainable parameters than existing methods; 4) New Evaluation Metric, fairly assessing the diversity and identity consistency. Experiments show Face2VoiceSync achieves both visual and audio state-of-the-art performances on a single 40GB GPU.

Zhaoqiang Xia, Hexiang Huang, Haoyu Chen et al.

Micro-gestures are unconsciously performed body gestures that can convey the emotion states of humans and start to attract more research attention in the fields of human behavior understanding and affective computing as an emerging topic. However, the modeling of human emotion based on micro-gestures has not been explored sufficiently. In this work, we propose to recognize the emotion states based on the micro-gestures by reconstructing the behavior patterns with a hypergraph-enhanced Transformer in a hybrid-supervised framework. In the framework, hypergraph Transformer based encoder and decoder are separately designed by stacking the hypergraph-enhanced self-attention and multiscale temporal convolution modules. Especially, to better capture the subtle motion of micro-gestures, we construct a decoder with additional upsampling operations for a reconstruction task in a self-supervised learning manner. We further propose a hypergraph-enhanced self-attention module where the hyperedges between skeleton joints are gradually updated to present the relationships of body joints for modeling the subtle local motion. Lastly, for exploiting the relationship between the emotion states and local motion of micro-gestures, an emotion recognition head from the output of encoder is designed with a shallow architecture and learned in a supervised way. The end-to-end framework is jointly trained in a one-stage way by comprehensively utilizing self-reconstruction and supervision information. The proposed method is evaluated on two publicly available datasets, namely iMiGUE and SMG, and achieves the best performance under multiple metrics, which is superior to the existing methods.

Haoyu Chen, Anna Little, Akin Narayan

This article introduces a novel, geometric approach for multi-manifold clustering (MMC), i.e. for clustering a collection of potentially intersecting, d-dimensional manifolds into the individual manifold components. We first compute a locality graph on d-simplices, using the dihedral angle in between adjacent simplices as the graph weights, and then compute infinity path distances in this simplex graph. This procedure gives a metric on simplices which we refer to as the largest angle path distance (LAPD). We analyze the properties of LAPD under random sampling, and prove that with an appropriate denoising procedure, this metric separates the manifold components with high probability. We validate the proposed methodology with extensive numerical experiments on both synthetic and real-world data sets. These experiments demonstrate that the method is robust to noise, curvature, and small intersection angle, and generally out-performs other MMC algorithms. In addition, we provide a highly scalable implementation of the proposed algorithm, which leverages approximation schemes for infinity path distance to achieve quasi-linear computational complexity.

Yu Guan, Zhiyu Yin, Haoyu Chen et al.

Troubleshooting performance problems of large model training (LMT) is immensely challenging, due to unprecedented scales of modern GPU clusters, the complexity of software-hardware interactions, and the data intensity of the training process. Existing troubleshooting approaches designed for traditional distributed systems or datacenter networks fall short and can hardly apply to real-world training systems. In this paper, we present PerfTracker, the first online troubleshooting system utilizing fine-grained profiling, to diagnose performance issues of large-scale model training in production. PerfTracker can diagnose performance issues rooted in both hardware (e.g., GPUs and their interconnects) and software (e.g., Python functions and GPU operations). It scales to LMT on modern GPU clusters. PerfTracker effectively summarizes runtime behavior patterns of fine-grained LMT functions via online profiling, and leverages differential observability to localize the root cause with minimal production impact. PerfTracker has been deployed as a production service for large-scale GPU clusters of O(10, 000) GPUs (product homepage https://help.aliyun.com/zh/pai/user-guide/perftracker-online-performance-analysis-diagnostic-tool). It has been used to diagnose a variety of difficult performance issues.

Sofoklis Kakouros, Haoyu Chen

This study examines the prosodic characteristics associated with winning and losing in post-match tennis interviews. Additionally, this research explores the potential to classify match outcomes solely based on post-match interview recordings using prosodic features and self-supervised learning (SSL) representations. By analyzing prosodic elements such as pitch and intensity, alongside SSL models like Wav2Vec 2.0 and HuBERT, the aim is to determine whether an athlete has won or lost their match. Traditional acoustic features and deep speech representations are extracted from the data, and machine learning classifiers are employed to distinguish between winning and losing players. Results indicate that SSL representations effectively differentiate between winning and losing outcomes, capturing subtle speech patterns linked to emotional states. At the same time, prosodic cues -- such as pitch variability -- remain strong indicators of victory.

Yuanyuan Peng, Aidi Lin, Meng Wang et al.

Inability to express the confidence level and detect unseen classes has limited the clinical implementation of artificial intelligence in the real-world. We developed a foundation model with uncertainty estimation (FMUE) to detect 11 retinal conditions on optical coherence tomography (OCT). In the internal test set, FMUE achieved a higher F1 score of 96.76% than two state-of-the-art algorithms, RETFound and UIOS, and got further improvement with thresholding strategy to 98.44%. In the external test sets obtained from other OCT devices, FMUE achieved an accuracy of 88.75% and 92.73% before and after thresholding. Our model is superior to two ophthalmologists with a higher F1 score (95.17% vs. 61.93% &71.72%). Besides, our model correctly predicts high uncertainty scores for samples with ambiguous features, of non-target-category diseases, or with low-quality to prompt manual checks and prevent misdiagnosis. FMUE provides a trustworthy method for automatic retinal anomalies detection in the real-world clinical open set environment.

Meng Wang, Tian Lin, Aidi Lin et al.

Previous foundation models for fundus images were pre-trained with limited disease categories and knowledge base. Here we introduce a knowledge-rich vision-language model (RetiZero) that leverages knowledge from more than 400 fundus diseases. For RetiZero's pretraining, we compiled 341,896 fundus images paired with texts, sourced from public datasets, ophthalmic literature, and online resources, encompassing a diverse range of diseases across multiple ethnicities and countries. RetiZero exhibits remarkable performance in several downstream tasks, including zero-shot disease recognition, image-to-image retrieval, AI-assisted clinical diagnosis,few-shot fine-tuning, and internal- and cross-domain disease identification. In zero-shot scenarios, RetiZero achieves Top-5 accuracies of 0.843 for 15 diseases and 0.756 for 52 diseases. For image retrieval, it achieves Top-5 scores of 0.950 and 0.886 for the same sets, respectively. AI-assisted clinical diagnosis results show that RetiZero's Top-3 zero-shot performance surpasses the average of 19 ophthalmologists from Singapore, China, and the United States. RetiZero substantially enhances clinicians' accuracy in diagnosing fundus diseases, in particularly rare ones. These findings underscore the value of integrating the RetiZero into clinical settings, where various fundus diseases are encountered.

Daniel Seita, Xinlei Pan, Haoyu Chen et al.

We present a novel Metropolis-Hastings method for large datasets that uses small expected-size minibatches of data. Previous work on reducing the cost of Metropolis-Hastings tests yield variable data consumed per sample, with only constant factor reductions versus using the full dataset for each sample. Here we present a method that can be tuned to provide arbitrarily small batch sizes, by adjusting either proposal step size or temperature. Our test uses the noise-tolerant Barker acceptance test with a novel additive correction variable. The resulting test has similar cost to a normal SGD update. Our experiments demonstrate several order-of-magnitude speedups over previous work.