Guang Li

Ren Tasai, Guang Li, Ren Togo et al.

We propose a novel continual self-supervised learning (CSSL) framework for simultaneously learning diverse features from multi-window-obtained chest computed tomography (CT) images and ensuring data privacy. Achieving a robust and highly generalizable model in medical image diagnosis is challenging, mainly because of issues, such as the scarcity of large-scale, accurately annotated datasets and domain shifts inherent to dynamic healthcare environments. Specifically, in chest CT, these domain shifts often arise from differences in window settings, which are optimized for distinct clinical purposes. Previous CSSL frameworks often mitigated domain shift by reusing past data, a typically impractical approach owing to privacy constraints. Our approach addresses these challenges by effectively capturing the relationship between previously learned knowledge and new information across different training stages through continual pretraining on unlabeled images. Specifically, by incorporating a latent replay-based mechanism into CSSL, our method mitigates catastrophic forgetting due to domain shifts during continual pretraining while ensuring data privacy. Additionally, we introduce a feature distillation technique that integrates Wasserstein distance-based knowledge distillation (WKD) and batch-knowledge ensemble (BKE), enhancing the ability of the model to learn meaningful, domain-shift-robust representations. Finally, we validate our approach using chest CT images obtained across two different window settings, demonstrating superior performance compared with other approaches.

Kangan Qian, Sicong Jiang, Yang Zhong et al. · tsinghua

Vision-Language Models (VLMs) show promise for autonomous driving, yet their struggle with hallucinations, inefficient reasoning, and limited real-world validation hinders accurate perception and robust step-by-step reasoning. To overcome this, we introduce \textbf{AgentThink}, a pioneering unified framework that integrates Chain-of-Thought (CoT) reasoning with dynamic, agent-style tool invocation for autonomous driving tasks. AgentThink's core innovations include: \textbf{(i) Structured Data Generation}, which establishes an autonomous driving tool library to automatically construct structured, self-verified reasoning data explicitly incorporating tool usage for diverse driving scenarios; \textbf{(ii) A Two-stage Training Pipeline}, employing Supervised Fine-Tuning (SFT) with Group Relative Policy Optimization (GRPO) to equip VLMs with the capability for autonomous tool invocation; and \textbf{(iii) Agent-style Tool-Usage Evaluation}, introducing a novel multi-tool assessment protocol to rigorously evaluate the model's tool invocation and utilization. Experiments on the DriveLMM-o1 benchmark demonstrate that AgentThink significantly boosts overall reasoning scores by \textbf{53.91%} and enhances answer accuracy by \textbf{33.54%}, while markedly improving reasoning quality and consistency. Furthermore, ablation studies and robust zero-shot/few-shot generalization experiments across various benchmarks underscore its powerful capabilities. These findings highlight a promising trajectory for developing trustworthy and tool-aware autonomous driving models. Code is available at https://github.com/curryqka/AgentThink.

Yawen Zou, Guang Li, Duo Su et al.

Dataset distillation (DD) condenses large datasets into compact yet informative substitutes, preserving performance comparable to the original dataset while reducing storage, transmission costs, and computational consumption. However, previous DD methods mainly focus on distilling information from images, often overlooking the semantic information inherent in the data. The disregard for context hinders the model's generalization ability, particularly in tasks involving complex datasets, which may result in illogical outputs or the omission of critical objects. In this study, we integrate vision-language methods into DD by introducing text prototypes to distill language information and collaboratively synthesize data with image prototypes, thereby enhancing dataset distillation performance. Notably, the text prototypes utilized in this study are derived from descriptive text information generated by an open-source large language model. This framework demonstrates broad applicability across datasets without pre-existing text descriptions, expanding the potential of dataset distillation beyond traditional image-based approaches. Compared to other methods, the proposed approach generates logically coherent images containing target objects, achieving state-of-the-art validation performance and demonstrating robust generalization. Source code and generated data are available in https://github.com/zou-yawen/Dataset-Distillation-via-Vision-Language-Category-Prototype/

Ayaka Tsutsumi, Guang Li, Ren Togo et al.

We propose a novel medical image classification method that integrates dual-model weight selection with self-knowledge distillation (SKD). In real-world medical settings, deploying large-scale models is often limited by computational resource constraints, which pose significant challenges for their practical implementation. Thus, developing lightweight models that achieve comparable performance to large-scale models while maintaining computational efficiency is crucial. To address this, we employ a dual-model weight selection strategy that initializes two lightweight models with weights derived from a large pretrained model, enabling effective knowledge transfer. Next, SKD is applied to these selected models, allowing the use of a broad range of initial weight configurations without imposing additional excessive computational cost, followed by fine-tuning for the target classification tasks. By combining dual-model weight selection with self-knowledge distillation, our method overcomes the limitations of conventional approaches, which often fail to retain critical information in compact models. Extensive experiments on publicly available datasets-chest X-ray images, lung computed tomography scans, and brain magnetic resonance imaging scans-demonstrate the superior performance and robustness of our approach compared to existing methods.

Mingzhuo Li, Guang Li, Jiafeng Mao et al.

Dataset distillation enables the training of deep neural networks with comparable performance in significantly reduced time by compressing large datasets into small and representative ones. Although the introduction of generative models has made great achievements in this field, the distributions of their distilled datasets are not diverse enough to represent the original ones, leading to a decrease in downstream validation accuracy. In this paper, we present a diversity-driven generative dataset distillation method based on a diffusion model to solve this problem. We introduce self-adaptive memory to align the distribution between distilled and real datasets, assessing the representativeness. The degree of alignment leads the diffusion model to generate more diverse datasets during the distillation process. Extensive experiments show that our method outperforms existing state-of-the-art methods in most situations, proving its ability to tackle dataset distillation tasks.

Guang Li, Ren Togo, Takahiro Ogawa et al.

Purpose: Manual annotation of gastric X-ray images by doctors for gastritis detection is time-consuming and expensive. To solve this, a self-supervised learning method is developed in this study. The effectiveness of the proposed self-supervised learning method in gastritis detection is verified using a few annotated gastric X-ray images. Methods: In this study, we develop a novel method that can perform explicit self-supervised learning and learn discriminative representations from gastric X-ray images. Models trained based on the proposed method were fine-tuned on datasets comprising a few annotated gastric X-ray images. Five self-supervised learning methods, i.e., SimSiam, BYOL, PIRL-jigsaw, PIRL-rotation, and SimCLR, were compared with the proposed method. Furthermore, three previous methods, one pretrained on ImageNet, one trained from scratch, and one semi-supervised learning method, were compared with the proposed method. Results: The proposed method's harmonic mean score of sensitivity and specificity after fine-tuning with the annotated data of 10, 20, 30, and 40 patients were 0.875, 0.911, 0.915, and 0.931, respectively. The proposed method outperformed all comparative methods, including the five self-supervised learning and three previous methods. Experimental results showed the effectiveness of the proposed method in gastritis detection using a few annotated gastric X-ray images. Conclusions: This paper proposes a novel self-supervised learning method based on a teacher-student architecture for gastritis detection using gastric X-ray images. The proposed method can perform explicit self-supervised learning and learn discriminative representations from gastric X-ray images. The proposed method exhibits potential clinical use in gastritis detection using a few annotated gastric X-ray images.

Chenyu You, Qingsong Yang, Hongming Shan et al.

Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past years, major efforts have been dedicated to the development of Low-Dose CT (LDCT) methods. However, the radiation dose reduction compromises the signal-to-noise ratio (SNR), leading to strong noise and artifacts that down-grade CT image quality. In this paper, we propose a novel 3D noise reduction method, called Structure-sensitive Multi-scale Generative Adversarial Net (SMGAN), to improve the LDCT image quality. Specifically, we incorporate three-dimensional (3D) volumetric information to improve the image quality. Also, different loss functions for training denoising models are investigated. Experiments show that the proposed method can effectively preserve structural and texture information from normal-dose CT (NDCT) images, and significantly suppress noise and artifacts. Qualitative visual assessments by three experienced radiologists demonstrate that the proposed method retrieves more detailed information, and outperforms competing methods.