Peng Ren

Zeyu Wang, Huiying Zhao, Peng Ren et al.

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment strategies are problematic and may cause harm to patients. To address this decision problem, we propose a new medical decision model based on historical data to help clinicians recommend the best reference option for real-time treatment. Our model combines offline reinforcement learning and deep reinforcement learning to solve the problem of traditional reinforcement learning in the medical field due to the inability to interact with the environment, while enabling our model to make decisions in a continuous state-action space. We demonstrate that, on average, the treatments recommended by the model are more valuable and reliable than those recommended by clinicians. In a large validation dataset, we find out that the patients whose actual doses from clinicians matched the decisions made by AI has the lowest mortality rates. Our model provides personalized and clinically interpretable treatment decisions for sepsis to improve patient care.

Peng Ren, Hai Yang

Generating long and stylized human motions in real time is critical for applications that demand continuous and responsive character control. Despite its importance, existing streaming approaches often operate directly in the raw motion space, leading to substantial computational overhead and making it difficult to maintain temporal stability. In contrast, latent-space VAE-Diffusion-based frameworks alleviate these issues and achieve high-quality stylization, but they are generally confined to offline processing. To bridge this gap, LILAC (Long-sequence Incremental Low-latency Arbitrary Motion Stylization via Streaming VAE-Diffusion with Causal Decoding) builds upon a recent high-performing offline framework for arbitrary motion stylization and extends it to an online setting through a latent-space streaming architecture with a sliding-window causal design and the injection of decoded motion features to ensure smooth motion transitions. This architecture enables long-sequence real-time arbitrary stylization without relying on future frames or modifying the diffusion model architecture, achieving a favorable balance between stylization quality and responsiveness as demonstrated by experiments on benchmark datasets. Supplementary video and examples are available at the project page: https://pren1.github.io/lilac/