Alcohol Intake Differentiates AD and LATE: A Telltale Lifestyle from Two Large-Scale DatasetsXinxing Wu, Chong Peng, Peter T. Nelson et al.
Alzheimer's disease (AD), as a progressive brain disease, affects cognition, memory, and behavior. Similarly, limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently defined common neurodegenerative disease that mimics the clinical symptoms of AD. At present, the risk factors implicated in LATE and those distinguishing LATE from AD are largely unknown. We leveraged an integrated feature selection-based algorithmic approach, to identify important factors differentiating subjects with LATE and/or AD from Control on significantly imbalanced data. We analyzed two datasets ROSMAP and NACC and discovered that alcohol consumption was a top lifestyle and environmental factor linked with LATE and AD and their associations were differential. In particular, we identified a specific subpopulation consisting of APOE e4 carriers. We found that, for this subpopulation, light-to-moderate alcohol intake was a protective factor against both AD and LATE, but its protective role against AD appeared stronger than LATE. The codes for our algorithms are available at https://github.com/xinxingwu-uk/PFV.
MambaTab: A Plug-and-Play Model for Learning Tabular DataMd Atik Ahamed, Qiang Cheng
Despite the prevalence of images and texts in machine learning, tabular data remains widely used across various domains. Existing deep learning models, such as convolutional neural networks and transformers, perform well however demand extensive preprocessing and tuning limiting accessibility and scalability. This work introduces an innovative approach based on a structured state-space model (SSM), MambaTab, for tabular data. SSMs have strong capabilities for efficiently extracting effective representations from data with long-range dependencies. MambaTab leverages Mamba, an emerging SSM variant, for end-to-end supervised learning on tables. Compared to state-of-the-art baselines, MambaTab delivers superior performance while requiring significantly fewer parameters, as empirically validated on diverse benchmark datasets. MambaTab's efficiency, scalability, generalizability, and predictive gains signify it as a lightweight, "plug-and-play" solution for diverse tabular data with promise for enabling wider practical applications.
1.6LGJun 4, 2021
Top-$k$ Regularization for Supervised Feature SelectionXinxing Wu, Qiang Cheng
Feature selection identifies subsets of informative features and reduces dimensions in the original feature space, helping provide insights into data generation or a variety of domain problems. Existing methods mainly depend on feature scoring functions or sparse regularizations; nonetheless, they have limited ability to reconcile the representativeness and inter-correlations of features. In this paper, we introduce a novel, simple yet effective regularization approach, named top-$k$ regularization, to supervised feature selection in regression and classification tasks. Structurally, the top-$k$ regularization induces a sub-architecture on the architecture of a learning model to boost its ability to select the most informative features and model complex nonlinear relationships simultaneously. Theoretically, we derive and mathematically prove a uniform approximation error bound for using this approach to approximate high-dimensional sparse functions. Extensive experiments on a wide variety of benchmarking datasets show that the top-$k$ regularization is effective and stable for supervised feature selection.
9.1LGApr 16, 2019
RES-PCA: A Scalable Approach to Recovering Low-rank MatricesChong Peng, Chenglizhao Chen, Zhao Kang et al.
Robust principal component analysis (RPCA) has drawn significant attentions due to its powerful capability in recovering low-rank matrices as well as successful appplications in various real world problems. The current state-of-the-art algorithms usually need to solve singular value decomposition of large matrices, which generally has at least a quadratic or even cubic complexity. This drawback has limited the application of RPCA in solving real world problems. To combat this drawback, in this paper we propose a new type of RPCA method, RES-PCA, which is linearly efficient and scalable in both data size and dimension. For comparison purpose, AltProj, an existing scalable approach to RPCA requires the precise knowlwdge of the true rank; otherwise, it may fail to recover low-rank matrices. By contrast, our method works with or without knowing the true rank; even when both methods work, our method is faster. Extensive experiments have been performed and testified to the effectiveness of proposed method quantitatively and in visual quality, which suggests that our method is suitable to be employed as a light-weight, scalable component for RPCA in any application pipelines.
Top-N Recommendation on GraphsZhao Kang, Chong Peng, Ming Yang et al.
Recommender systems play an increasingly important role in online applications to help users find what they need or prefer. Collaborative filtering algorithms that generate predictions by analyzing the user-item rating matrix perform poorly when the matrix is sparse. To alleviate this problem, this paper proposes a simple recommendation algorithm that fully exploits the similarity information among users and items and intrinsic structural information of the user-item matrix. The proposed method constructs a new representation which preserves affinity and structure information in the user-item rating matrix and then performs recommendation task. To capture proximity information about users and items, two graphs are constructed. Manifold learning idea is used to constrain the new representation to be smooth on these graphs, so as to enforce users and item proximities. Our model is formulated as a convex optimization problem, for which we need to solve the well-known Sylvester equation only. We carry out extensive empirical evaluations on six benchmark datasets to show the effectiveness of this approach.
Top-N Recommendation with Novel Rank ApproximationZhao Kang, Qiang Cheng
The importance of accurate recommender systems has been widely recognized by academia and industry. However, the recommendation quality is still rather low. Recently, a linear sparse and low-rank representation of the user-item matrix has been applied to produce Top-N recommendations. This approach uses the nuclear norm as a convex relaxation for the rank function and has achieved better recommendation accuracy than the state-of-the-art methods. In the past several years, solving rank minimization problems by leveraging nonconvex relaxations has received increasing attention. Some empirical results demonstrate that it can provide a better approximation to original problems than convex relaxation. In this paper, we propose a novel rank approximation to enhance the performance of Top-N recommendation systems, where the approximation error is controllable. Experimental results on real data show that the proposed rank approximation improves the Top-$N$ recommendation accuracy substantially.
18.1IRJan 19, 2016
Top-N Recommender System via Matrix CompletionZhao Kang, Chong Peng, Qiang Cheng
Top-N recommender systems have been investigated widely both in industry and academia. However, the recommendation quality is far from satisfactory. In this paper, we propose a simple yet promising algorithm. We fill the user-item matrix based on a low-rank assumption and simultaneously keep the original information. To do that, a nonconvex rank relaxation rather than the nuclear norm is adopted to provide a better rank approximation and an efficient optimization strategy is designed. A comprehensive set of experiments on real datasets demonstrates that our method pushes the accuracy of Top-N recommendation to a new level.
Robust Subspace Clustering via Tighter Rank ApproximationZhao Kang, Chong Peng, Qiang Cheng
Matrix rank minimization problem is in general NP-hard. The nuclear norm is used to substitute the rank function in many recent studies. Nevertheless, the nuclear norm approximation adds all singular values together and the approximation error may depend heavily on the magnitudes of singular values. This might restrict its capability in dealing with many practical problems. In this paper, an arctangent function is used as a tighter approximation to the rank function. We use it on the challenging subspace clustering problem. For this nonconvex minimization problem, we develop an effective optimization procedure based on a type of augmented Lagrange multipliers (ALM) method. Extensive experiments on face clustering and motion segmentation show that the proposed method is effective for rank approximation.